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NCT ID: NCT03746613 Completed - Clinical trials for Sensorineural Hearing Loss

Clinal Evaluation of Navigation Based Functional Ear Surgery Using Image Guided and Robotically Assisted Techniques

EAR2OS
Start date: September 24, 2018
Phase: N/A
Study type: Interventional

To assess the feasibility of achieving a minimally invasive access to the inner ear through the navigation-based HEARO procedure and subsequently insert the electrode array of the cochlear implant through the access.

NCT ID: NCT03744455 Completed - Clinical trials for Anesthesia Complication

Influence of Resident's Degree of Formation on the Quality of Care Delivered to the Patients.

Start date: September 1, 2018
Phase:
Study type: Observational

The aim of this study is to evaluation the influence of the resident in anesthesiology's degree of formation on the quality of care delivered to the patient.

NCT ID: NCT03744299 Completed - Cancer Clinical Trials

The Interest of Cancer Patients and Caregivers in Acupuncture: a Survey

ACTIVATE
Start date: November 20, 2018
Phase: N/A
Study type: Interventional

Cancer and cancer treatments are accompanied by several possible side effects, such as nausea, hot flashes, fatigue, drowsiness, etc. Complementary and integrative therapies, such as acupuncture, could be used to manage these symptoms. The aim of this study for our research team is to have an idea of the interest of cancer patients and caregivers in acupuncture. This is a prospective, interventional study. Cancer patients and caregivers will be approached at the day care clinic by a health care worker to participate in this study. They will be asked to complete a questionnaire about their interest in acupuncture and their motivation, what symptoms they would need it for, where they would like this acupuncture to take place, whether they are willing to pay for it, and whether they would be interested in an information session about acupuncture.

NCT ID: NCT03743064 Completed - Clinical trials for Non Small Cell Lung Cancer

A Study to Evaluate the Efficacy and Safety of Anamorelin HCl for the Treatment of Malignancy Associated Weight Loss and Anorexia in Adult Patients With Advanced Non-Small Cell Lung Cancer (NSCLC)

Start date: December 18, 2018
Phase: Phase 3
Study type: Interventional

Multicenter, randomized, double-blind, parallel-group, placebo-controlled study to evaluate the efficacy and safety of anamorelin HCl. Approximately 316 patients with advanced NSCLC with cachexia will be randomized 1:1 to anamorelin HCl 100 mg or placebo, taken orally once daily (QD) for a total of 24 weeks. Patients will be instructed to take the study drug at least 1 hour before their first meal of the day

NCT ID: NCT03742713 Completed - Cancer Clinical Trials

Efficacy Study of CPC634 (CriPec® Docetaxel) in Platinum Resistant Ovarian Cancer

CINOVA
Start date: October 1, 2018
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine whether CPC634 (CriPec® docetaxel) is effective in the treatment of patients with advanced epithelial ovarian cancer who are resistant to prior platinum-based chemotherapy .

NCT ID: NCT03742336 Completed - Healthy Clinical Trials

Study of PF-04965842 Effect on Dabigatran Pharmacokinetics in Healthy Participants

Start date: November 21, 2018
Phase: Phase 1
Study type: Interventional

This is a Phase 1, randomized, 2 way crossover, single dose, open label study of the effect of PF 04965842 on dabigatran PK in healthy participants. Participants will be randomized to 1 of 2 treatment sequences as described below. A total of 20 healthy male and/or female participants will be enrolled in the study so that 10 participants will be enrolled in each treatment sequence. Each treatment sequence will consist of 2 periods that are each 3 days in duration. The total duration of participation from the Screening Visit to Day 7 will be a maximum of 35 days and from the Screening Visit to Follow-up Contact/Visit will be a maximum of 70 days.

NCT ID: NCT03736993 Completed - NSCLC, Stage IIIA Clinical Trials

Metabolomics Predict Therapy Response

PROLUNG
Start date: May 28, 2018
Phase: N/A
Study type: Interventional

Complete resection is the mainstay of treatment for stage I-IIIA resectable non-small cell lung cancer (NSCLC). However rates of recurrence of disease are high, with five-year survival rates ranging between 73% (stage IA) and 24% (stage IIIA). Therefore, a prognostic biological marker that stratifies between NSCLC patients whom surgery cures versus patients in whom surgery would be futile due to early disease relapse after surgery is eagerly awaited. The primary objective of this prospective study is to establish a prognostic marker of early disease progression after complete surgical resection in patients with stages I to IIIA NSCLC. For this purpose the investigator will compare the metabolic profile with disease progression or death within one year after complete surgical resection to the patients with a progression free survival. Furthermore the investigator will evaluate the changes in the metabolic profile after surgery and if changes in this metabolic profile over time can predict disease recurrence before it becomes clinically apparent.

NCT ID: NCT03732859 Completed - Clinical trials for Idiopathic Pulmonary Fibrosis

PROOF-Registry New and Extended Belgium -Luxembourg

PROOF-NEXT
Start date: January 9, 2018
Phase:
Study type: Observational [Patient Registry]

A Prospective Observational Registry to describe the disease course and outcomes of Idiopathic Pulmonary Fibrosis patients in a real-world clinical setting.

NCT ID: NCT03729362 Completed - Clinical trials for Pompe Disease (Late-onset)

A Study Comparing ATB200/AT2221 With Alglucosidase Alfa/Placebo in Adult Subjects With Late-onset Pompe Disease

PROPEL
Start date: December 4, 2018
Phase: Phase 3
Study type: Interventional

This is a phase 3 double-blind randomized study to study the efficacy and safety of intravenous ATB200 Co-administered with oral AT2221 in adult subjects with Late Onset Pompe Disease compared with Alglucosidase Alfa/placebo.

NCT ID: NCT03728036 Completed - Stroke Clinical Trials

What do Stroke Survivors Actually Learn When Regaining Walking Ability After Stroke? The TARGET Phase I Study

TARGET
Start date: November 1, 2018
Phase:
Study type: Observational

Phase I: Exploring what stroke survivors exactly learn when recovering the ability to stand and walk.