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NCT ID: NCT00649298 Completed - Clinical trials for End Stage Renal Disease

A Clinical Trial of IntensiVE Dialysis

ACTIVE
Start date: May 2008
Phase: Phase 4
Study type: Interventional

This study will assess clinical outcomes of extended weekly hours of haemodialysis (>= 24 hours per week) compared with standard hours of haemodialysis (<=18 hours/week) in people with ESKD.

NCT ID: NCT00647270 Completed - Clinical trials for Rheumatoid Arthritis

Study Comparing 80 mg of Adalimumab With Placebo, and Demonstrating the Non-inferiority of Monthly 80 mg Adalimumab Dosing Compared With 40 mg Adalimumab Every Other Week Dosing

Start date: December 2007
Phase: Phase 3
Study type: Interventional

To demonstrate the efficacy of 80 mg adalimumab monthly dosing compared with placebo and demonstrate the non-inferiority of monthly dosing of 80 mg adalimumab compared with dosing of 40 mg adalimumab every other week.

NCT ID: NCT00646542 Completed - Clinical trials for Diabetes Mellitus, Type 2

Safety and Tolerability of Vildagliptin Versus Placebo in Patients With Type 2 Diabetes and Moderate or Severe Renal Insufficiency

Start date: March 2005
Phase: Phase 3
Study type: Interventional

This clinical trial is designed to provide additional information on the safety and tolerability of vildagliptin (50 mg once daily (qd)) when used in patients with type 2 diabetes mellitus (T2DM) and moderate or severe renal insufficiency.

NCT ID: NCT00645788 Completed - Cystic Fibrosis Clinical Trials

Study to Evaluate the Safety and Efficacy of Ciprofloxacin (Inhaled) in Patients With Cystic Fibrosis

Start date: May 2008
Phase: Phase 2
Study type: Interventional

To evaluate the change in forced expiratory volume (FEV1) from baseline to Day 28-30 between Cipro Inhale-treated and placebo-treated subjects after a 4-week treatment period.

NCT ID: NCT00645736 Completed - Chronic Hepatitis B Clinical Trials

CHARM: Chronic Hepatitis B Antihepadnaviral Resistance Mutation Study

CHARM
Start date: February 2008
Phase: N/A
Study type: Observational

This study has the aim of describing viral mutation profiles in patients diagnosed with chronic hepatitis B receiving antihepadnaviral therapy.

NCT ID: NCT00644982 Completed - Clinical trials for Depressive Disorder, Major

A Comparison of Sertraline Versus Venlafaxine XR in the Treatment of Major Depression

Start date: October 2002
Phase: Phase 4
Study type: Interventional

To assess the comparative efficacy of sertraline versus venlafaxine XR on measures of quality of life.

NCT ID: NCT00644605 Completed - Clinical trials for Hypertension, Pulmonary

A Study to Assess the Efficacy and Safety of 20, 40, and 80mg of Sildenafil Three Times a Day in the Treatment of Pulmonary Arterial Hypertension

Start date: October 2002
Phase: Phase 3
Study type: Interventional

To evaluate the effect of three doses of oral sildenafil (20, 40 and 80 mg three times a day [TID]) on exercise capacity, as measured by the 6-Minute Walk test, as well as the safety and tolerability, after 12 weeks of treatment in subjects with pulmonary arterial hypertension who are aged 18 years and over. To investigate the plasma concentration-effect relationship and to determine the population pharmacokinetic (PK) parameters.

NCT ID: NCT00643929 Completed - Clinical trials for Purpura, Thrombocytopaenic, Idiopathic

LENS - Long-term Eltrombopag Observational Study

LENS
Start date: February 2007
Phase: N/A
Study type: Observational

A long term observational ocular safety study in adults who have received study medication (either active drug or placebo) in a phase II or III clinical study evaluating eltrombopag. The study will follow subjects for 2.5 years following their last ocular assessment on their prior treatment study (regardless of the therapeutic indication) and will describe long-term ocular safety with respect to changes in the lenses over time from all subjects.

NCT ID: NCT00643331 Completed - Osteoporosis Clinical Trials

The Effect of Exercise in Postmenopausal Women With Low Bone Density

Start date: February 2001
Phase: Phase 2
Study type: Interventional

This clinical trial aims to evaluate the effects of a 12 month gym- and home-based exercise program on bone density and falls risk factors in postmenopausal women with low bone density. It is hypothesised that the exercise program will lead to improvements in bone density and falls risk factors such as balance and muscle strength compared with usual care.

NCT ID: NCT00643201 Completed - Venous Thrombosis Clinical Trials

Efficacy and Safety Study of Apixaban for the Treatment of Deep Vein Thrombosis or Pulmonary Embolism

Start date: July 2008
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the effects of an investigational blood thinner, apixaban, in preventing venous thromboembolic (VTE) recurrence or death in patients with deep vein thrombosis (DVT) or pulmonary embolism (PE)