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Cystic Fibrosis clinical trials

View clinical trials related to Cystic Fibrosis.

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NCT ID: NCT03822455 Not yet recruiting - Cystic Fibrosis Clinical Trials

A Phase 2b Randomised, Placebo Controlled Study of OligoG in Patients With Cystic Fibrosis (CFmised, Double-blind, Parallel-group Study of Alginate Oligosaccharide)

Start date: April 3, 2019
Phase: Phase 2/Phase 3
Study type: Interventional

A double-blind, randomised study of OligoG DPI compared to placebo DPI, both on top of standard-of-care, to assess safety, efficacy and tolerability. Adult patients with Cystic Fibrosis will be included in the study.

NCT ID: NCT03820752 Recruiting - Diabetes Clinical Trials

Vaccination Coverage and Level of Protection in Patients at Risk

Start date: October 2014
Phase:
Study type: Observational

The purpose of this study is to determine 1. vaccination coverage of recommended vaccines (routine childhood vaccines and vaccines against seasonal flu and pneumococci) in children with chronic diseases (allergy, cystic fibrosis, diabetes mellitus type 1, congenital heart disease, immunocompromised and solid organ transplant patients) 2. the level of protection against measles, mumps, rubella and pertussis in children with chronic diseases. 3. vaccination coverage of recommended vaccines (diphtheria, tetanus, pertussis and vaccines against seasonal flu and pneumococci) in adults with chronic diseases (nephropathy, diabetes mellitus, COPD, heart failure, HIV and solid organ transplant patients) 4. the level of protection against diphtheria, tetanus and pertussis in adults with chronic diseases.

NCT ID: NCT03820349 Recruiting - Cystic Fibrosis Clinical Trials

Cystic Fibrosis and Cognitive Function

Start date: May 7, 2018
Phase:
Study type: Observational

The long-term goal of this project is to examine the effects of cystic fibrosis (CF) and cystic fibrosis related diabetes (CFRD) on brain structure and function

NCT ID: NCT03809091 Recruiting - Cystic Fibrosis Clinical Trials

WGS of Korean Idiopathic Bronchiectasis

WGS_UNK_BE
Start date: January 2019
Phase:
Study type: Observational [Patient Registry]

Whole genome sequencing of Korean patients with idiopathic bronchiectasis and their family will perform to identify disease-causing variants.

NCT ID: NCT03801993 Not yet recruiting - Cystic Fibrosis Clinical Trials

Multicenter Study of Patient-reported Gastrointestinal Symptoms in People With Cystic Fibrosis

GALAXY
Start date: May 1, 2019
Phase:
Study type: Observational

This is a prospective, multicenter, observational study designed to collect gastrointestinal related data in patients with Cystic Fibrosis (CF).

NCT ID: NCT03800459 Completed - Cystic Fibrosis Clinical Trials

Effect of a Family Empowerment Program on Coping, Problem Solving in Parents, and Quality of Life in Children With Cystic Fibrosis

Start date: December 14, 2016
Phase: N/A
Study type: Interventional

Parents of children with cystic fibrosis (CF) experience high levels of stress and problems. Family empowerment interventions provide important support for many patients with CF and their families. However,there is a lack of research exploring the effects of such empowerment programs on coping, and Problem Solving among parents, and Quality of Life in Children with CF. The present study aimed to assess the effect of a family empowerment program-based nursing intervention on parents coping with stress and problem solving, and quality of life children with CF.

NCT ID: NCT03797677 Completed - Cystic Fibrosis Clinical Trials

MN4000 for Treatment of CF and MND Patients in the Home Setting

Start date: March 9, 2017
Phase: N/A
Study type: Interventional

The study was a non-randomized open label pilot study. It was an observational design conducted at one (1) site in the US. All enrolled subjects received treatment with the MN4000. This pilot study evaluated subject satisfaction with the therapy and adherence to the therapy during the 90-day treatment period, and also collected clinical outcome data. Outcomes were assessed before, during and after the MN4000 treatment period.

NCT ID: NCT03795363 Recruiting - Cystic Fibrosis Clinical Trials

Orkambi Treatment in 2 to 5 Year Old Children With CF

Start date: January 2019
Phase:
Study type: Observational

The purpose of this observational research study is to determine the effects of clinically prescribed Orkambi treatment on 2 to 5 year old children homozygous for the F508del Mutations in the Cystic fibrosis transmembrane conductance regulator (CFTR) gene on sleeping energy expenditure, growth status and gut health and function.

NCT ID: NCT03783286 Recruiting - Cystic Fibrosis Clinical Trials

Ivacaftor Treatment in 1 to 2 Year Old CF Subjects

Start date: January 12, 2019
Phase:
Study type: Observational

The purpose of this research study is to determine the effects of clinically prescribed ivacaftor treatment on 1 to 2-year-old children with CF and gating mutations on sleeping energy expenditure, growth status and gut health and function.

NCT ID: NCT03782909 Not yet recruiting - Cystic Fibrosis Clinical Trials

Evaluation of a Behavioural Intervention Using App Technology in CF

EAT-CF
Start date: January 7, 2019
Phase: N/A
Study type: Interventional

Cystic Fibrosis (CF) is a lifelong condition which causes the lungs and digestive system to become clogged with thick, sticky mucus. This leads to recurrent chest infections and reduced nutrient absorption from food. The average age at death is 31 years, usually from respiratory failure. The nutritional status of people with CF (PWCF) is important to help them live healthier and longer. It is recommended that adults with CF achieve a BMI of 23 for males and 22 for females. However, fewer than 50% of adults with CF achieved that target BMI despite effective nutritional support to help weight gain. There is a clear need for a behavioural intervention that can help PWCF use the available nutritional support. This is a feasibility study to try out a multi-component behavioural intervention supported by a nutrition app. The intervention is designed to help PWCF use their nutritional support to gain weight. It will focus on testing the methods and procedures to be used on a larger scale, improving the behavioural intervention and estimating how many people are needed for the larger trial. Eligible patients will be invited to participate, and the investigators anticipate recruiting 6 participants. The participants will have 6 weeks of intensive intervention, which will include a mix of clinic visits, home visits and telephone calls followed by 6 weeks of maintenance phase. Data will be collected during clinic visits at baseline, week 6 and week 12 along with weight monitoring at home. The investigators will interview each participant at the end of the study period to improve the intervention and study processes based on participant feedback. The investigators hypothesised that using a nutrition app, along with regular input from a dietitian, will help PWCF to use the available nutritional support.