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Hypertension, Pulmonary clinical trials

View clinical trials related to Hypertension, Pulmonary.

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NCT ID: NCT03667794 Completed - Clinical trials for Pulmonary Hypertension

Evaluation of Novel Lung Function Parameters in Patients With Pulmonary Hypertension (PH)

Start date: July 1, 2015
Phase:
Study type: Observational

Little is known about affection of small airways in patients with pulmonary hypertension as well as the ideal diagnostic approach. The investigators therefore aimed to evaluate novel or not widely used lung function tests for the evaluation of airway function in patients with PH.

NCT ID: NCT03667391 Recruiting - Clinical trials for The Geodemographics of CTEPH in Taiwan

Taiwan Cohort - Chronic ThromboEmbolic Pulmonary Hypertension Registry

Start date: January 17, 2018
Phase:
Study type: Observational [Patient Registry]

The diagnosis of chronic thromboembolic pulmonary hypertension (CTEPH) is difficult for numerous reasons and is related with a poor prognosis. In Taiwan, the incidence of CTEPH and its clinical features are unknown. This study aims at evaluating the prevalence, clinical characteristics, and management of CTEPH in a Taiwanese cohort. Primary objective: - To investigate the geodemographics of CTEPH in Taiwan Secondary objectives: - To characterize the demographics and clinical presentation of patients with CTEPH - To describe the real-world management and treatment outcome of patients with CTEPH - To identify the risk factors of CTEPH - To assess the relationship between risk factors/patients' characteristics and clinical outcomes for CTEPH - To evaluate the prognosis of CTEPH in Taiwan using survival assessment

NCT ID: NCT03649932 Not yet recruiting - Clinical trials for Pulmonary Hypertension

Enteral L Citrulline Supplementation in Preterm Infants - Safety, Efficacy and Dosing

Start date: September 10, 2018
Phase: Phase 1
Study type: Interventional

Oral L-citrulline supplementation may prevent and/or decrease the severity of chronic lung disease associated pulmonary hypertension in preterm infants. Since oral L-citrulline supplementation has never been studied in preterm infants before, the side effect profile and appropriate dosing is still unknown. In this pilot study, we will determine the safety profile, efficacy and appropriate dosing of oral L-citrulline in preterm infants. In future, information from this study will be utilized to conduct a randomized placebo-controlled trial to evaluate the role of L-citrulline supplementation in treating BPD_PH.

NCT ID: NCT03648385 Not yet recruiting - Clinical trials for Pulmonary Arterial Hypertension

Effects of DHEA in Pulmonary Hypertension

EDIPHY
Start date: November 1, 2018
Phase: Phase 2
Study type: Interventional

The goal of this crossover trial is to determine whether the study drug dehydroepiandrosterone (DHEA) improves right ventricular longitudinal strain measured by cardiac magnetic resonance imaging at 18 weeks compared to placebo and to assess side effects and safety in pulmonary arterial hypertension.

NCT ID: NCT03637218 Enrolling by invitation - Clinical trials for Pulmonary Hypertension

Acute Exposure of High Altitude on Cardiac Output

Start date: July 1, 2018
Phase: N/A
Study type: Interventional

Randomized crossover trial in patients with Pulmonary Hypertension (PAH, CTEPH) to assess the acute response High Altitude (Säntis; 2500m above sea level) on non-invasive cardiac output assessments by Finapres® NOVA Technology at rest and under exercise

NCT ID: NCT03637192 Enrolling by invitation - Clinical trials for Pulmonary Hypertension

Acute Exposure of High Altitude on Cognitive Function

Start date: July 1, 2018
Phase: N/A
Study type: Interventional

Randomized crossover Trial in patients with pulmonary arterial hypertension (PAH) or chronic thromboembolic pulmonary Hypertension (CTEPH) to assess the acute response to High Altitude (2500m above sea level) on cognitive functions

NCT ID: NCT03637179 Enrolling by invitation - Clinical trials for Pulmonary Hypertension

Acute Exposure to High Altitude on Pulmonary Artery Pressure and Right Heart Function (Echo) Under Exercise

Start date: July 1, 2018
Phase: N/A
Study type: Interventional

Randomized crossover Trial in patients with Pulmonary Hypertension (PAH, CTEPH) to assess the acute response to High Altitude (2500m above sea level) on pulmonary artery pressure and right heart function (Echo) under exercise.

NCT ID: NCT03637166 Enrolling by invitation - Clinical trials for Pulmonary Hypertension

Acute Exposure to High Altitude on Pulmonary Artery Pressure and Right Heart Function (Echo)

Start date: July 1, 2018
Phase: N/A
Study type: Interventional

Randomized crossover Trial in patients with Pulmonary Hypertension (PAH, CTEPH) to assess the acute response to High Altitude ("Säntis"; 2500m above sea level) on pulmonary artery pressure and right heart function (echo)

NCT ID: NCT03637153 Enrolling by invitation - Clinical trials for Pulmonary Hypertension

Acute Exposure to High Altitude on Exercise Capacity

Start date: July 1, 2018
Phase: N/A
Study type: Interventional

Randomized crossover Trial in patients with Pulmonary Hypertension (PAH, CTEPH) to assess the acute response to High Altitude (2500m above sea level) in constant loaded exercise capacity.

NCT ID: NCT03637140 Enrolling by invitation - Clinical trials for Pulmonary Hypertension

Acute Exposure of Simulated Hypoxia on Pulmonary Artery Pressure and Right Heart Function (Echo) Under Exercise

Start date: July 1, 2018
Phase: N/A
Study type: Interventional

Randomized crossover Trial in patients with Pulmonary Hypertension (PAH, CTEPH) to assess the acute response to simulated altitude (FiO2:15.1, equivalent to 2500m above sea level) on pulmonary artery pressure and right heart function (echo) under exercise.