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NCT ID: NCT00389181 Completed - Clinical trials for Arteriovenous Malformations, Cerebral

A Randomized Trial of Unruptured Brain AVMs

ARUBA
Start date: October 2006
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine if medical management is better than invasive therapy for improving the long-term outcome of patients with unruptured brain arteriovenous malformations.

NCT ID: NCT00388726 Completed - Breast Cancer Clinical Trials

E7389 Versus Treatment of Physician's Choice in Patients With Locally Recurrent or Metastatic Breast Cancer

Start date: November 2006
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare Overall Survival (OS), Progression Free Survival (PFS), objective tumor response rate, duration of response, and safety in patients treated with E7389 versus the Treatment of Physician's Choice (TPC) in patients with locally recurrent or metastatic breast cancer.

NCT ID: NCT00387764 Completed - Clinical trials for Carcinoma, Renal Cell

Extension Study to VEG105192 to Assess Pazopanib in Patients With Advanced/Metastatic Renal Cell Cancer

Start date: September 2006
Phase: Phase 3
Study type: Interventional

This is an open-label, international, multi-center study designed to provide access to pazopanib for subjects who have been enrolled in the Phase III renal cell carcinoma study (VEG105192) and have progressed on placebo. Subjects will receive 800 mg pazopanib once daily. The study treatment will continue until subjects experience disease progression, unacceptable toxicity, withdrawal of consent, or death. The primary objective of the study is to evaluate the safety and tolerability of pazopanib for the treatment of renal cell carcinoma. The secondary objectives of the study are to assess response rate (defined as complete response or partial response), progression-free survival, and overall survival. Response rates will be collected per investigator assessment (no central review). Subjects will have a CT/MRI scan every 6 weeks until week 24 and every 12 weeks thereafter.

NCT ID: NCT00386854 Completed - Inflammation Clinical Trials

Metabolic Study of Concentric and Eccentric Muscle Training

Start date: April 2003
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the metabolic and anti-inflammatory effects of eccentric endurance exercise and to compare them with those of concentric exercise in healthy sedentary individuals.

NCT ID: NCT00385736 Completed - Ulcerative Colitis Clinical Trials

Efficacy and Safety of Adalimumab in Subjects With Moderately to Severely Acute Ulcerative Colitis

Start date: November 2006
Phase: Phase 3
Study type: Interventional

The objective of this study is to assess the efficacy and safety of adalimumab for the induction of clinical remission in subjects with moderately to severely active ulcerative colitis.

NCT ID: NCT00384982 Completed - Clinical trials for Myocardial Infarction

Myocardial Stem Cell Administration After Acute Myocardial Infarction (MYSTAR) Study

MYSTAR
Start date: January 2005
Phase: Phase 2
Study type: Interventional

The MYocardial STem cell Administration after acute myocardial infaRction (MYSTAR) study is a multicenter, prospective, randomized, single-blind clinical trial designed to compare the early and late intracoronary or combined (percutaneous intramyocardial and intracoronary) administration of bone marrow-derived stem cells to patients after acute myocardial infarction with reopened infarct-related artery.

NCT ID: NCT00384319 Completed - Cardiac Arrest Clinical Trials

Pilot Clinical Study of the LRS ThermoSuitâ„¢ System in Post Arrest Patients

Start date: October 2006
Phase: Phase 1
Study type: Interventional

The purpose of this study is to determine if the Life Recovery Systems Thermosuit(R) System is able to quickly and conveniently cool patients who are comatose after resuscitation from cardiac arrest.

NCT ID: NCT00384176 Completed - Colorectal Cancer Clinical Trials

First Line Metastatic Colorectal Cancer Therapy in Combination With FOLFOX

HORIZON III
Start date: August 30, 2006
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this study is to see if Cediranib in combination with FOLFOX is effective in treating metastatic colorectal cancer and to see how it compares with Avastin (Bevacizumab) in combination with FOLFOX.

NCT ID: NCT00382889 Completed - Asthma Clinical Trials

As Needed Beclomethasone/Salbutamol Combination in Single Inhaler for Mild Persistent Asthma

Start date: August 2002
Phase: Phase 3
Study type: Interventional

The aim of this study is to reveal that inhaled corticosteroid therapy combined with a short-acting beta2- agonist given on a symptom driven basis is as effective as traditional asthma therapy. Thus, three advantages will be achieved: 1. better compliance with treatment since patients will most likely have to administer the treatment less frequently, 2. maximum pharmacological effect with the least amount of drug and 3. less economic burden on health care providers.

NCT ID: NCT00382317 Completed - Diagnostic Imaging Clinical Trials

A Clinical Study of Iobitridol in Patients Undergoing Multislice Computed Tomography (CT) Abdominal Angiography

Start date: August 2006
Phase: Phase 4
Study type: Interventional

This is a clinical study of iobitridol in patients undergoing multislice CT (MSCT) abdominal angiography.