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NCT ID: NCT02665455 Completed - Diabetes Mellitus Clinical Trials

FreeStyle Libre in Pregnancy Study

FLIPS
Start date: January 2016
Phase: N/A
Study type: Interventional

To evaluate the point accuracy of the FreeStyle Libre Flash Glucose Monitoring System when used at home by pregnant women with diabetes.

NCT ID: NCT02664272 Completed - Osteoarthritis Clinical Trials

Intraoperative Case Series Study: Trial Rasp Position Versus SL-PLUS™ MIA Ti/HA Femoral Hip Stem Position

Start date: April 6, 2016
Phase:
Study type: Observational

A prospective, multicenter, observational study using the SL-PLUS™ MIA Ti/HA femoral hip stem with the appropriate set of instruments.

NCT ID: NCT02663375 Completed - Aortic Stenosis Clinical Trials

ACURATE TA™ Valve Implantation Registry: SAVI 2

TA-SAVI2
Start date: November 2013
Phase:
Study type: Observational [Patient Registry]

Post-market registry on ACURATE TA™ Transapical Aortic Bioprosthesis and ACURATE TA™ Delivery System implantation in patients presenting severe symptomatic aortic stenosis to collect continued surveillance data pertaining to safety and performance of the device.

NCT ID: NCT02663076 Completed - Clinical trials for Chronic Kidney Disease (CKD)

Factor XA - Inhibition in RENal Patients With Non-valvular Atrial Fibrillation - Observational Registry

XARENO
Start date: April 2016
Phase:
Study type: Observational [Patient Registry]

The multicenter registry will collect clinical data from 1600 patients with non valvular atrial fibrillation (NVAF) and chronic kidney disease (eGFR 15-49 mL/min per 1.73 m2). The overall objective of this registry is to assess chronic kidney disease (CKD) progression and clinical outcomes with regard to anticoagulation strategies in NVAF patients with eGFR 15-49 mL/min per 1.73 m2 in routine clinical practice.

NCT ID: NCT02662985 Completed - Psoriatic Arthritis Clinical Trials

Study of Power Doppler Ultrasound (PDUS) to Measure Response of Secukinumab Treatment in Patients With Active Psoriatic Arthritis (PsA)

PDUS
Start date: August 22, 2016
Phase: Phase 3
Study type: Interventional

This study was designed to leverage the sensitivity of ultrasonography available in clinical practice setting to better describe the time course of response to secukinumab (150 mg and 300 mg) on joint synovitis and enthesitis in PsA patients with an inadequate response to non-biologic DMARDs. PDUS changes in joint synovitis will be assessed using the global Outcome Measures in Rheumatology (OMERACT)-European League against Rheumatism (EULAR) synovitis score (GLOESS) and changes in joint enthesitis were assessed using the OMERACT enthesitis score.

NCT ID: NCT02662114 Completed - Clinical trials for Diabetes Mellitus, Type 2

Investigating the Effectiveness of Tresiba® (Insulin Degludec) After Switching Basal Insulin in a Population With Type 1 or Type 2 Diabetes Mellitus

EU-TREAT
Start date: December 8, 2015
Phase:
Study type: Observational

This trial is conducted in Europe. The aim of this trial is to investigate the effectiveness of Tresiba® (insulin degludec) after switching basal insulin in a population with type 1 or type 2 diabetes mellitus. EU-TREAT (EUropean TREsiba AudiT)

NCT ID: NCT02659527 Completed - Prostate Cancer Clinical Trials

PET/MRI in Patients With Suspected Prostate Cancer

Start date: January 2016
Phase: Phase 3
Study type: Interventional

This diagnostic clinical trial will be conducted according to a randomized, prospective, controlled, double-arm, single-centre design. The control will be implemented by comparing the PET/MRI results with the histopathological finding after radical prostatectomy (positive state), the assumed absence of a relevant prostate cancer focus if PET/MRI guided biopsy and standard biopsy are negative (negative state) and/or the detection of a biochemical tumor relapse [rising prostate specific antigen (PSA) after PSA nadir; secondary objective].

NCT ID: NCT02657434 Completed - Clinical trials for Non-Small Cell Lung Cancer

A Study of Atezolizumab in Combination With Carboplatin or Cisplatin + Pemetrexed Compared With Carboplatin or Cisplatin + Pemetrexed in Participants Who Are Chemotherapy-Naive and Have Stage IV Non-Squamous Non-Small Cell Lung Cancer (NSCLC) (IMpower 132)

Start date: April 30, 2016
Phase: Phase 3
Study type: Interventional

This is a randomized, Phase III, multicenter, open-label study designed to evaluate the safety and efficacy of atezolizumab in combination with cisplatin or carboplatin + pemetrexed compared with treatment with cisplatin or carboplatin + pemetrexed in participants who are chemotherapy-naive and have Stage IV non-squamous NSCLC. Eligible participants will be randomized by a 1:1 ratio into 2 groups: Arm A (Atezolizumab + Carboplatin or Cisplatin + Pemetrexed) and Arm B (Carboplatin or Cisplatin + Pemetrexed). The study will be conducted in two phases: Induction Phase and Maintenance Phase.

NCT ID: NCT02656238 Completed - Clinical trials for Chronic Thromboembolic Pulmonary Hypertension

New International CTEPH Database

Start date: February 2015
Phase:
Study type: Observational [Patient Registry]

The New International CTEPH Database is a prospective, observational multi-center disease registry run by the International CTEPH Association (ICA), which will collect data in chronic thromboembolic pulmonary hypertension (CTEPH) patients worldwide. The registry will run for approximately 5 years. Its objective is to provide an overview on epidemiology of CTEPH, mode of diagnosis and treatment approaches worldwide as well as determinants of long-term outcomes as measured by New York Heart Association (NYHA) functional class and survival. The data collected will improve the knowledge and understanding of this condition, support the further development of diagnosis and treatment guidelines for patients with CTEPH, and contribute to improving patient care in the long-term.

NCT ID: NCT02655315 Completed - Parkinson Disease Clinical Trials

Conservative Iron Chelation as a Disease-modifying Strategy in Parkinson's Disease

FAIRPARKII
Start date: February 9, 2016
Phase: Phase 2
Study type: Interventional

This study evaluates the effect of iron chelation as a therapeutic strategy to slow the progression of Parkinson's disease. Half of participants will receive the deferiprone to 15 mg / kg twice daily morning and evening (30mg / kg per day), while the other half will receive a placebo. The treatment lasts nine months.