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Parkinson Disease clinical trials

View clinical trials related to Parkinson Disease.

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NCT ID: NCT03624920 Recruiting - Parkinson Disease Clinical Trials

Safety and Efficacy of THN102 in Patients With Parkinson's Disease and Excessive Daytime Sleepiness

Start date: July 12, 2018
Phase: Phase 2
Study type: Interventional

This is a randomized, placebo-controlled, 3-way cross-over phase IIa trial comparing two dose levels of THN102 to placebo in patients suffering from Parkinson's disease associated with excessive daytime sleepiness.

NCT ID: NCT03623841 Recruiting - Stroke Clinical Trials

Training With Exergame and Treadmill on Executive Function and Dual-task Performance

Start date: August 12, 2018
Phase: N/A
Study type: Interventional

This study aimed to investigate the effects of dual-task training with exergame and treadmill on executive function and dual-task performance in individuals with PD and stroke and discuss the correlation between the change values of executive function and dual-task performance after training. Besides, investigate cortical activation after training.

NCT ID: NCT03623672 Recruiting - Parkinson Disease Clinical Trials

North American Prodromal Synucleinopathy Consortium

NAPS
Start date: August 1, 2018
Phase:
Study type: Observational [Patient Registry]

This study will enroll participants with idiopathic rapid eye movement (REM) sleep behavior disorder (RBD), for the purpose of preparing for a clinical trial of neuroprotective treatments against synucleinopathies.

NCT ID: NCT03623386 Recruiting - Parkinson Disease Clinical Trials

Effect of Mental Imagery Training on Brain Plasticity and Motor Function in Individuals With Parkinson's Disease

Start date: August 10, 2018
Phase: N/A
Study type: Interventional

Effect of Mental Imagery Training on Brain Plasticity and Motor Function in Individuals with Parkinson's Disease: A functional MRI investigation.

NCT ID: NCT03622840 Recruiting - Parkinson Disease Clinical Trials

Impact of Individual Cognitive Remediation for Parkinson's Disease

Start date: July 12, 2018
Phase: N/A
Study type: Interventional

This is an interventional clinical trial that will be conducted as a pilot project. Investigators hope to conduct the study to obtain at least 10 study completers. The plan is to screen 20 Parkinson's Disease (PD) patients attending the Academic Health Care Center (AHCC) at NYIT College of Osteopathic Medicine clinic and enroll the eligible candidates based on the inclusion and exclusion criteria. Subjects will have 11 study visits over the 11-week period. Subjects cognition will be assessed using a paper-based Test of Memory and Learning (TOMAL) tool. The same tool will be used to asses and compare the cognition at baseline, and end study visits. The weekly 30-mins of cognitive remediation exercises will be done using the Brain. HQ cognitive remediation software.

NCT ID: NCT03621046 Not yet recruiting - Parkinson Disease Clinical Trials

Use of Low-dose Zolpidem in Parkinson's Disease

Start date: August 1, 2018
Phase: Phase 2
Study type: Interventional

This study will evaluate the motor and cognitive benefits of low-dose zolpidem in Parkinson's.

NCT ID: NCT03618901 Not yet recruiting - Parkinson Disease Clinical Trials

Rock Steady Boxing vs. PD SAFEx

Start date: September 30, 2018
Phase: N/A
Study type: Interventional

This study evaluates the effect on Rock Steady Boxing (RSB) and PD SAFEx on Parkinson's disease.

NCT ID: NCT03616145 Recruiting - Parkinson Disease Clinical Trials

Effects of Osteopathic Manipulative Treatment (OMT) on Gait Biomechanics in Parkinson's Disease

(OMT/PD)
Start date: July 1, 2018
Phase: N/A
Study type: Interventional

Parkinson's disease (PD) is a neurological disorder that puts individuals at high risk for injuries and long-term disabilities as a result of a fall or other trauma. Injuries sustained from falls account for many deaths as well as thousands of hospital admissions and nursing home stays every month. Quality of life and even longevity itself is reduced due to the resulting surgeries, immobility, complications and even cognitive impairments that can follow. The proposed study will explore beneficial impact of a treatment modality (OMM/OMT) that may significantly reduce the morbidity of this condition by comparing 6 weeks of OMT versus 6 weeks light touch intervention versus 6 weeks care as usual to improve gait in individuals with PD. Gait will be measured at mid-treatment, post-treatment and 4-week follow-up.

NCT ID: NCT03613038 Recruiting - Parkinson Disease Clinical Trials

A Systematic Investigation of Phonetic Complexity Effects on Articulatory Motor Performance in Progressive Dysarthria

Start date: July 15, 2017
Phase: N/A
Study type: Interventional

The goal is to improve the fundamental knowledge about articulatory motor performance in people with Lou Gehrig's disease (also known as ALS) and Parkinson's disease (PD), in order to develop more sensitive assessments for progressive speech loss, which may lead to the improved timing of speech therapies.

NCT ID: NCT03611569 Recruiting - Healthy Clinical Trials

Lu AF82422 in Healthy Non-Japanese and Japanese Subjects and in Patients With Parkinson's Disease

Start date: July 25, 2018
Phase: Phase 1
Study type: Interventional

The purpose of this study is to investigate the safety of a single dose of Lu AF82422, how well it is tolerated, how the drug effects the body and what the body does to the drug in healthy non-Japanese and Japanese subjects and in patients with Parkinson's disease