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NCT ID: NCT05293613 Completed - Clinical trials for Determine the Efficacy and Safety of SWL in Renal Stones Larger Than 2 cm in Pediatric Age Group

Extracorporeal Shock Wave Lithotripsy for Treatment of Large Pediatric Renal Pelvic Stone Burden More Than 2 cm

Start date: April 1, 2022
Phase: N/A
Study type: Interventional

Extracorporeal shock wave lithotripsy (SWL) was first described for pediatric nephrolithiasis in 1986; SWL has been a mainstay of treatment for both renal and ureteral calculi in children . SWL is currently regarded as first-line therapy for most renal and upper ureteral calculi <2.0 cm according to the EAU/ESPU guidelines . Meanwhile, the American Urological Association (AUA) considers SWL to be a first-line option along with URS for renal or ureteral calculi <2.0 cm, and a first-line option along with PNL for renal calculi >2.0 cm . The shock waves are better transmitted and spontaneous clearance of fragmented stones in pediatric kidneys is higher than adults' kidneys; thus, SWL treatment seems likely to be more successful in the pediatric population compared to the adult population .Younger age is associated with better stone clearance in children treated with SWL, and this is related mostly to increased ureteral compliance (shorter, more elastic and distensible) and shorter skin-to-stone distance .

NCT ID: NCT05296382 Completed - Clinical trials for Relative Bioavailability

Bioavailability of Tebipenem (SPR994) Crushed Tablet

Start date: April 1, 2022
Phase: Phase 1
Study type: Interventional

The purpose of this study is to measure the amount of the antibiotic, tebipenem (SPR994) that is bioavailable after crushing the tablet and administering through a feeding tube with and without tube feeds.

NCT ID: NCT05298319 Completed - Hypoxia Clinical Trials

The 90% Effective Flow of High Flow Nasal Oxygenation (HFNO) During Sedated Bronchoscopy

HFNO
Start date: April 1, 2022
Phase: N/A
Study type: Interventional

Patients undergoing sedated bronchoscopy were randomized into six groups (10 Liters/minute [L/min], 20 L/min, 30 L/min, 40 L/min, 50 L/min, 60 L/min). The primary outcome was the incidence of hypoxemia.

NCT ID: NCT05298579 Completed - Pain Clinical Trials

Yoga Exercises Applied With Two Different Technological Access

Start date: April 1, 2022
Phase: N/A
Study type: Interventional

Yoga, a form of exercise designed to bring balance and health to the physical, mental, emotional and spiritual dimensions of the individual, will benefit many white-collar workers by using popular technological environments to increase overall physical activity and well-being. The aim of this study is to examine the effects of yoga exercises applied with two different technological access in white-collar employees on musculoskeletal pain, fatigue, sleep quality, stress level, quality of life and work efficiency.

NCT ID: NCT05298917 Completed - Cornea Clinical Trials

Influence of Silicone Hydrogel Extended Contact Lens Wear on Corneal Sensitivity

Start date: April 1, 2022
Phase: N/A
Study type: Interventional

Soft contact lens wear reduces the amount of oxygen reaching the eye, which may have an influence on corneal sensitivity. The aim of this study is to measure corneal sensitivity with means of liquid jet esthesiometry at baseline and after 6 days of continuous, extended contact lens wear.

NCT ID: NCT05299021 Completed - Postoperative Pain Clinical Trials

Serratus Anterior Plane Block for Modified Radical Mastectomy: Double-point VS Single-point

Start date: April 1, 2022
Phase: N/A
Study type: Interventional

Nowadays, the incidence of breast cancer is the first number of malignant tumors, and the primary treatment method is surgery. As is known to all, less postoperative complications and enhanced recovery are closely related to effective analgesia. However, postoperative patients often experience moderate pain, while associated with axillary discomfort. Serratus Anterior Plane Block (SAPB) relieves postoperative pain, but traditional single point block method has no effect on axillary discomfort. Therefore, it is necessary to try double point blocks to explore their impact on postoperative analgesia and axillary comfort. This RCT will recruit patients proposed to undergo Modified Radical Mastectomy (MRM) and be randomized to single point or double point groups to evaluate their postoperative pain score and axillary comfort in order to provide clinical guidance.

NCT ID: NCT05299216 Completed - Low Back Pain Clinical Trials

Effect of Diaphragm Manual Therapy With Conventional Physical Therapy in Chronic Non-Specific Low Back Pain Patients

Start date: April 1, 2022
Phase: N/A
Study type: Interventional

A randomized single-blind clinical study will be performed. A sample size of 34 patients including only male gender, will be taken from various clinical settings of Faisalabad. Non-probability purposive sampling technique will be used. Patients will be randomly allocated into two groups. Treatment Group A will perform Conventional Physical Therapy and Diaphragm Manual Therapy and Group B will perform Conventional Physical Therapy and Sham Diaphragm Manual Therapy. Numerical Pain Rating Scale and lumbar range of motion scores will be assessed at pre-treatment, 2nd-week post-treatment and 4th-week post-treatment. Oswestry Disability Index scores and Short Form 12 Health Survey Questionnaire will be assessed at pre-treatment and 4th-week post-treatment. Statistical analysis will be performed on Statistical Package for the Social Sciences Version 25.

NCT ID: NCT05300516 Completed - Hypertension Clinical Trials

Vagus Nerve-guided Robotic-assisted Splenectomy and Azygoportal Disconnection

VNRSD
Start date: April 1, 2022
Phase: N/A
Study type: Interventional

This study aimed to evaluate whether vagus nerve-guided robotic-assisted splenectomy and azygoportal disconnection is effective and safe, and to determine whether a reduction in the incidence of postoperative complications of the digestive system improves postoperative quality of life compared with conventional robotic-assisted splenectomy and azygoportal disconnection.

NCT ID: NCT05300867 Completed - Stroke, Acute Clinical Trials

Robotic Rehabilitation Treatment of Stroke Patients

Start date: April 1, 2022
Phase: N/A
Study type: Interventional

Storke results in severe deterioration in quality of life and exercise. Severe disorders need to be treated as soon as possible and they need to be rehabilitated quickly in order for motor functions to develop properly. In the acute / subacute phase, patients are given robotic treatment. In addition to the study of mtoros functions, the study of gait and codination is the primary result. Patients treated with soft exoskeleton receive 15 treatments and movement testing is performed continuously. Members of the control group receive standard rehabilitation therapy. After 3 weeks, both groups will participate in a control study and then in a repeat control study at week 6. Our main goal is to compare the results and determine the efficiency of the robotic device.

NCT ID: NCT05300906 Completed - Well-being Clinical Trials

The Effectiveness of Engagement-based Personalization of a Digital Mental Health Intervention

Start date: April 1, 2022
Phase: N/A
Study type: Interventional

This study will investigate the effectiveness of an engagement-based personalized 2-week mobile wellbeing intervention, vs the effectiveness of a non-personalized 2-week mobile wellbeing intervention.