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Breast Cancer clinical trials

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NCT ID: NCT00009763 Active, not recruiting - Breast Cancer Clinical Trials

Monoclonal Antibody Therapy, Cyclosporine, and Paclitaxel in Treating Patients With Recurrent or Refractory Metastatic Breast Cancer

Start date: March 2001
Phase: Phase 1
Study type: Interventional

RATIONALE: Monoclonal antibodies can locate tumor cells and either kill them or deliver tumor-killing substances to them without harming normal cells. Combining monoclonal antibody therapy with cyclosporine and paclitaxel may be an effective treatment for metastatic breast cancer. PURPOSE: Phase I trial to study the effectiveness of radiolabeled monoclonal antibody therapy, cyclosporine, and paclitaxel in treating patients who have recurrent or refractory metastatic breast cancer.

NCT ID: NCT00006369 Active, not recruiting - Breast Cancer Clinical Trials

ERA-923 in Treating Postmenopausal Women With Metastatic Breast Cancer

Start date: June 2000
Phase: Phase 2
Study type: Interventional

RATIONALE: Estrogen can stimulate the growth of breast cancer cells. Hormone therapy using ERA-923 may fight breast cancer by blocking the uptake of estrogen by the tumor cells. PURPOSE: Randomized phase II trial to study the effectiveness of ERA-923 in treating postmenopausal women who have metastatic breast cancer that no longer responds to tamoxifen.

NCT ID: NCT00006120 Active, not recruiting - Breast Cancer Clinical Trials

Docetaxel or Paclitaxel in Treating Women With Unresectable Locally Advanced or Metastatic Breast Cancer

Start date: May 2000
Phase: Phase 2
Study type: Interventional

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Randomized phase II trial to compare the effectiveness of two different regimens of docetaxel or paclitaxel in treating women who have unresectable locally advanced or metastatic breast cancer.

NCT ID: NCT00006030 Active, not recruiting - Breast Cancer Clinical Trials

Comparison of Four Different Treatment Regimens in Treating Women With Stage I Breast Cancer

Start date: January 1992
Phase: Phase 3
Study type: Interventional

RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Estrogen can stimulate the growth of breast cancer cells. Hormone therapy using tamoxifen may fight breast cancer by blocking the uptake of estrogen by the tumor cells. Combining radiation therapy and tamoxifen with surgery may kill more tumor cells. It is not yet known which treatment regimen is most effective for stage I breast cancer. PURPOSE: Randomized phase III trial to compare the effectiveness of four different treatment regimens in treating women who have stage I breast cancer.

NCT ID: NCT00005821 Active, not recruiting - Breast Cancer Clinical Trials

Sentinel Lymph Node Biopsy to Assess Axillary Lymph Nodes in Women With Stage I or Stage II Breast Cancer

Start date: December 1998
Phase: Phase 2
Study type: Interventional

RATIONALE: Diagnostic procedures such as sentinel lymph node biopsy may improve the ability to detect breast cancer and determine the extent of disease. PURPOSE: Phase II trial to study the effectiveness of sentinel lymph node biopsy to assess axillary lymph nodes in women who have stage I or stage II breast cancer.

NCT ID: NCT00005600 Active, not recruiting - Breast Cancer Clinical Trials

Axillary Drainage Following Lymph Node Dissection in Women With Stage I or Stage II Breast Cancer

Start date: November 1997
Phase: N/A
Study type: Interventional

RATIONALE: The use of axillary drains may help to prevent complications following axillary lymph node dissection. PURPOSE: This randomized clinical trial is comparing three methods of axillary drainage to see how well they work following lymph node dissection in women with stage I or stage II breast cancer.

NCT ID: NCT00005581 Active, not recruiting - Breast Cancer Clinical Trials

Combination Chemotherapy in Treating Women With Stage II or Stage III Breast Cancer

Start date: June 2000
Phase: Phase 3
Study type: Interventional

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. It is not yet known which regimen of chemotherapy is more effective for breast cancer. PURPOSE: Randomized phase III trial to compare the effectiveness of two regimens of combination chemotherapy in treating women who have stage II or stage III breast cancer.

NCT ID: NCT00005058 Active, not recruiting - Breast Cancer Clinical Trials

Enhanced Ultrasound in Determining Extent of Disease in Women With Primary Breast Cancer

Start date: August 1997
Phase: N/A
Study type: Interventional

RATIONALE: New imaging procedures, such as enhanced ultrasound may improve the ability to determine the extent of breast cancer. PURPOSE: Diagnostic study of enhanced ultrasound in women who have locally advanced primary breast cancer.

NCT ID: NCT00005054 Active, not recruiting - Breast Cancer Clinical Trials

Temozolomide in Treating Women With Advanced Breast Cancer

Start date: May 1998
Phase: Phase 2
Study type: Interventional

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase II trial to study the effectiveness of temozolomide in treating women who have advanced breast cancer.

NCT ID: NCT00004207 Active, not recruiting - Breast Cancer Clinical Trials

Liposomal Daunorubicin in Treating Patients With Metastatic Breast Cancer

Start date: December 1997
Phase: Phase 1
Study type: Interventional

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase I trial to study the effectiveness of liposomal daunorubicin in treating patients who have metastatic breast cancer.