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Breast Cancer clinical trials

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NCT ID: NCT00003854 Completed - Breast Cancer Clinical Trials

Prognostic Study of Sentinel Lymph Node and Bone Marrow Metastases in Women With Stage I or Stage IIA Breast Cancer

Start date: April 1999
Phase: Phase 3
Study type: Interventional

RATIONALE: Biopsy of sentinel lymph nodes and bone marrow may improve the ability to detect and determine the extent of cancer. PURPOSE: Phase III prognostic study of sentinel lymph node metastases and bone marrow metastases in women who have stage I or stage IIA breast cancer.

NCT ID: NCT00003830 Completed - Breast Cancer Clinical Trials

Surgery to Remove Sentinel Lymph Nodes With or Without Removing Lymph Nodes in the Armpit in Treating Women With Breast Cancer

Start date: May 1999
Phase: Phase 3
Study type: Interventional

RATIONALE: Removing the sentinel lymph nodes and examining them under a microscope may help plan more effective surgery for breast cancer. It is not yet known if surgery to remove the sentinel lymph nodes is more effective with or without removal of the lymph nodes in the armpit in treating breast cancer. PURPOSE: Randomized phase III trial to compare the effectiveness of surgery to remove the sentinel lymph nodes with or without removal of lymph nodes in the armpit in treating women who have breast cancer.

NCT ID: NCT00003796 Completed - Breast Cancer Clinical Trials

Irofulven in Treating Patients With Metastatic Breast Cancer

Start date: May 1999
Phase: Phase 2
Study type: Interventional

Phase II trial to study the effectiveness of irofulven in treating patients who have metastatic breast cancer. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.

NCT ID: NCT00003787 Completed - Breast Cancer Clinical Trials

Women's Healthy Eating and Living Study

Start date: March 1995
Phase:
Study type: Observational

RATIONALE: Dietary fats, fruits, vegetables, and fiber may affect the risk of breast cancer recurrence. PURPOSE: Randomized clinical trial to determine the effectiveness of a diet rich in vegetables, fruit, and fiber and low in fat in women who have been treated for stage I, stage II, or stage III breast cancer.

NCT ID: NCT00003782 Completed - Breast Cancer Clinical Trials

Combination Chemotherapy in Treating Women With Stage I, Stage II, or Stage IIIA (cT1-3, N0-1, M0) Breast Cancer and Positive Axillary Lymph Nodes

Start date: March 1999
Phase: Phase 3
Study type: Interventional

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Giving combination chemotherapy after surgery may kill any tumor cells remaining following surgery. It is not yet known which regimen of combination chemotherapy is more effective in treating breast cancer with positive axillary lymph nodes. PURPOSE: Randomized phase III trial to compare the effectiveness of different regimens of combination chemotherapy in treating women who have undergone surgery for stage I, stage II, or stage IIIA breast cancer with positive axillary lymph nodes.

NCT ID: NCT00003771 Completed - Breast Cancer Clinical Trials

Hormone Replacement Therapy and the Risk of Breast Cancer Recurrence in Women With Previous Early Stage Breast Cancer

Start date: September 1997
Phase: Phase 3
Study type: Interventional

RATIONALE: Hormone replacement therapy is effective for relieving symptoms of menopause. It is not yet known if hormone replacement therapy increases the risk of breast cancer recurrence in women previously treated for early stage breast cancer. PURPOSE: Randomized phase III trial to determine the risk of breast cancer recurrence in women with previous early stage breast cancer who are receiving hormone replacement therapy for menopause symptoms.

NCT ID: NCT00003761 Completed - Breast Cancer Clinical Trials

Vaccine Therapy in Treating Patients With Metastatic Breast Cancer

Start date: March 3, 1999
Phase: Phase 1
Study type: Interventional

This protocol is designed to evaluate the side effects of rV-DF3/MUC1 and to determine the safest dose which should be used in the treatment of breast cancer.

NCT ID: NCT00003752 Completed - Breast Cancer Clinical Trials

Bexarotene in Treating Patients With Metastatic Breast Cancer

Start date: October 1998
Phase: Phase 2
Study type: Interventional

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Randomized phase II trial to study the effectiveness of bexarotene in treating patients who have metastatic breast cancer.

NCT ID: NCT00003736 Completed - Breast Cancer Clinical Trials

MRI for Detecting Cancer in Women Who Are at High Risk of Developing Breast Cancer

Start date: June 1999
Phase: N/A
Study type: Interventional

RATIONALE: Screening tests may help doctors detect cancer cells early and plan more effective treatment for breast cancer. Diagnostic procedures such as MRI may improve the ability to detect breast cancer. PURPOSE: Screening and diagnostic trial to study the effectiveness of MRI scans in women who are at high risk for developing breast cancer.

NCT ID: NCT00003730 Completed - Breast Cancer Clinical Trials

Vinorelbine Plus Fluorouracil in Treating Women With Metastatic Breast Cancer

Start date: December 1998
Phase: N/A
Study type: Interventional

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. PURPOSE: Randomized clinical trial to study the effectiveness of vinorelbine plus fluorouracil in treating women who have metastatic breast cancer that has been previously treated with at least one regimen of chemotherapy.