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Breast Cancer clinical trials

View clinical trials related to Breast Cancer.

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NCT ID: NCT06125353 Completed - Breast Cancer Clinical Trials

The Effect of Melatonin Supplementation on Fatigue Symptoms During Chemotherapy Treatment of Breast Cancer Patients

Start date: January 1, 2022
Phase: N/A
Study type: Interventional

The aim of the present 3-month randomized, placebo-controlled trial was to evaluate whether adherence to Mediterranean Diet (MD) together with melatonin oral treatment or plaebo, would ameliorate Cancer Related Fatigue in Breast Cancer patients receiving chemotherapy treatment.

NCT ID: NCT06123416 Completed - Healthy Clinical Trials

Emotion Regulation and Cancer Caregiving

Start date: January 16, 2019
Phase:
Study type: Observational [Patient Registry]

The purpose of the study is to determine how the behaviors of cancer caregivers can impact patients.

NCT ID: NCT06119633 Completed - Breast Cancer Clinical Trials

Implant-based Breast Reconstruction and Mastectomy With Fat Grafting After Breast Conserving Surgery and Radiotherapy

Start date: June 2007
Phase: N/A
Study type: Interventional

Higher rates of complications and poorer cosmetic outcomes have been reported after salvage mastectomy and implant-based versus autologous reconstruction in patients previously exposed to radiation therapy (i) on the breast as adjuvant treatment after breast conserving surgery (BCS) or (ii) on thoracic wall for Hodgkin Lymphoma (HL). Nevertheless, selected patients with favourable preoperative soft-tissue assessment may benefit from alloplastic reconstruction and fat grafting that has been suggested as an effective technique to promote the regeneration of irradiated tissues. The aims of this study are to assess: 1. the feasibility of implant-based breast reconstruction and fat grafting after mastectomy (simple mastectomy, nipple-sparing and skin-sparing mastectomy) 2. oncological safety of implant-based breast reconstruction and fat grafting.

NCT ID: NCT06110832 Completed - Breast Cancer Clinical Trials

The Effect of Mindfulness-based Yoga and Meditation on Some Parameters in Breast Cancer Patients

Start date: May 11, 2023
Phase: N/A
Study type: Interventional

The purpose of this study was to evaluate the effect of mindfulness-based meditation and yoga on stress, self-esteem, body image and sexual adjustment in breast cancer patients.

NCT ID: NCT06104189 Completed - Breast Cancer Clinical Trials

Prospective Ultrafast MRI Radiomics for Breast Cancer

Start date: October 1, 2021
Phase:
Study type: Observational [Patient Registry]

The goal of this prospective study is to investigate the performance of ultrafast MRI radiomics in classifying histological factors and subtypes of breast cancer compared with standard MRI among radiologists with varying experience. The written informed consent was obtained from all participant. We extracted 1618 radiomic features from ultrafast and standard contrast-enhanced MRI before treatment. Classification of hormonal receptors, human epidermal growth factor receptor 2, and Ki67 status and subtypes was evaluated using the area under the receiver-operating characteristic curve (AUC) with the DeLong test.

NCT ID: NCT06103032 Completed - Breast Cancer Clinical Trials

Survival of BCS vs Mx in Asymptomatic Screen-detected NPBC

Start date: January 1, 2022
Phase:
Study type: Observational

We performed this study on a consecutive cohort of women with asymptomatic screen-detected NPBC. The clinicopathological characteristics, 10-year relapse-free survival (RFS) and overall survival (OS) were compared between BCS and Mx patients among different subgroups.

NCT ID: NCT06101732 Completed - Breast Cancer Clinical Trials

LIMBO : Breast Reconstruction by Lipomodeling Alone or With Flap: Evaluation in Franche-Comté

LIMBO
Start date: May 5, 2022
Phase:
Study type: Observational

The Limbo study is a retrospective descriptive study which aims to establish the current state of breast reconstruction surgery at the Besançon University Hospital and Hôpital Nord Franche-Comté, between October 2017 and December 2021.

NCT ID: NCT06095414 Completed - Breast Cancer Clinical Trials

Prospective Radiomics Study for Breast Cancer

Start date: June 1, 2020
Phase:
Study type: Observational [Patient Registry]

The goal of this prospective study is to develop MRI-based models representing tumor microenvironment in participants with invasive breast cancer. The main purpose of this study is to analyze the association of diffusion-, T2-, and dynamic contrast-enhanced T1-weighted images of 3T MRI before treatment with the immunohistochemical reactivity of tumor microenvironment including the extracellular matrix and immune cells of core-needle biopsy specimens For this purpose, investigators extract 16145 radiomic features from the intratumoral and peritumoral regions on MRI of participants with invasive breast cancer before treatment.

NCT ID: NCT06090630 Completed - Breast Carcinoma Clinical Trials

MR Correlated Spectroscopic Imaging for Diagnosing Breast Cancer

Start date: July 31, 2017
Phase: Early Phase 1
Study type: Interventional

This trial studies how well an imaging technique called magnetic resonance (MR) spectroscopic imaging works in identifying breast cancer in women with benign or suspicious areas in the breast. Magnetic resonance imaging (MRI) is a diagnostic tool used to investigate the location of tumors in different organs. Since radiological pictures do not have sufficient information for tumor grades, invasive procedure such as biopsy is performed on patients with breast cancers for diagnosis. Breast tissue contains water, fat, and chemicals known as metabolites. MR spectroscopic imaging may help to characterize the various breast metabolite steady state levels and identify the differences between necrosis and tumor recurrence, which is difficult using radiological procedures such as MRI.

NCT ID: NCT06086340 Completed - Breast Cancer Clinical Trials

Study to Compare Overall Survival in Medicare Patients With Metastatic Breast Cancer Treated With a Medicine Called Palbociclib in Combination With Aromatase Inhibitor and Aromatase Inhibitor by Itself.

Start date: September 29, 2023
Phase:
Study type: Observational

A retrospective study of de-identified (to preserve patient privacy) patient information from the SEER-Medicare Database to compare overall survival of first line palbociclib + aromatase inhibitor (AI) therapy versus AI therapy alone treatment in women or men aged 65 and older with newly diagnosed hormone receptor positive/human epidermal growth factor receptor 2 negative (HR+/HER2-) metastatic breast cancer (MBC) in the United States