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Breast Cancer clinical trials

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NCT ID: NCT00204477 Completed - Breast Cancer Clinical Trials

Soy Protein and Breast Cancer Risk Reduction

Start date: April 2002
Phase: Phase 2
Study type: Interventional

Soy consumption has been associated with reduced risk for developing breast cancer. Ovarian hormones and breast density are considered breast cancer risk markers. We propose to test the hypothesis that consumption of soy protein reduces ovarian steroid hormones and results in a corresponding reduction in breast density comparing to casein protein.

NCT ID: NCT00203502 Completed - Breast Cancer Clinical Trials

Primary Systemic Therapy in Operable/Locally Advanced Breast Cancer

Start date: September 2005
Phase: Phase 2
Study type: Interventional

The main purpose of this study is to find out what effects taking the drug bevacizumab together with two chemotherapeutic agents, docetaxel and cyclophosphamide followed by doxorubicin alone before surgery will on breast cancer. Bevacizumab will be given for twelve weeks in combination with chemotherapy then it ill be held during the administration of doxorubicin. Twenty-eight to fifty-six days after undergoing surgery, all patients will receive nine three-weekly infusions of bevacizumab.

NCT ID: NCT00203372 Completed - Breast Cancer Clinical Trials

Neoadjuvant TAC Plus or Minus Bevacizumab(AVF3299)

Start date: May 2005
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the safety of the TAC-bevacizumab combination and investigate whether changes in gene expression, or the expression of specific biomarkers, are either predictive of response to bevacizumab or indicative of response.

NCT ID: NCT00202059 Completed - Breast Cancer Clinical Trials

Effects of Zometa and Physical Activity on Bone Density in Women Receiving Chemotherapy for Breast Cancer

Start date: June 2003
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the effect of zoledronic acid and physical activity on preventing bone loss in women aged 40 - 55 who are receiving chemotherapy for breast cancer. The primary objective is to compare the percent change in the lumbar spine bone mineral density (BMD) from baseline to 12 months for women who are randomized to either: Group A) intravenous zoledronic acid, oral calcium carbonate, and vitamin D, or Group B) a prescribed physical activity program, oral calcium carbonate and vitamin D.

NCT ID: NCT00202046 Completed - Breast Cancer Clinical Trials

Predictors of Lymphedema Following Breast Cancer Surgery

Start date: January 2003
Phase: N/A
Study type: Observational

The purpose of this study evaluate which factors play a role in lymphedema development among women who have had axillary surgery for breast cancer. Potential risk factors for women who have developed lymphedema will be compared to risk factors among women who have not developed lymphedema after breast cancer surgery.

NCT ID: NCT00201942 Completed - Breast Cancer Clinical Trials

PET Imaging to Determine the Role of PET in the Assessment of Regional Disease in Breast Cancer (PET PREDICT Trial)

Start date: February 2005
Phase: Phase 3
Study type: Interventional

The overall goal of this study is to determine how FDG-PET can be incorporated into the assessment of the axilla in the staging and treatment of women with early stage breast cancer. A multicentre, prospective, diagnostic accuracy study will be conducted evaluating the ability of positronic emission tomography using fluorodeoxyglucose (FDG-PET) to detect the presence or absence of axillary lymph node metastases in newly diagnosed breast cancer patients with no clinical evidence of spread of disease beyond the breast.

NCT ID: NCT00201929 Completed - Breast Cancer Clinical Trials

A Decision Aid for Women With Early Stage Breast Cancer

Start date: April 2002
Phase: Phase 3
Study type: Interventional

To enhance information transfer and decision making for women with breast cancer.

NCT ID: NCT00201890 Completed - Breast Cancer Clinical Trials

Trial of Decongestive Lymphatic Therapy for Lymphedema in Women With Breast Cancer "DELTA STUDY"

Start date: March 2003
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy, safety and impact on quality of life of decongestive lymphatic therapy (DLT) in women who have completed treatment for breast cancer and present with lymphedema. This is a multicentre trial enrolling 100 patients randomized to receive conservative care for arm lymphedema (Canadian Guidelines) with or without decongestive lymphatic therapy performed by a professional who has received training and certification in the technique of lymphatic draining massage. Duration: One year after the last patient is randomized.

NCT ID: NCT00201864 Completed - Breast Cancer Clinical Trials

Exemestane in Combination With Fulvestrant in Postmenopausal Women With Hormone Sensitive Advanced Breast Cancer

Start date: September 2005
Phase: Phase 2
Study type: Interventional

The purpose of this trial is to evaluate time to progression in women with hormone responsive advanced breast cancer treated with a combination of exemestane and fulvestrant.

NCT ID: NCT00201851 Completed - Breast Cancer Clinical Trials

Adjuvant Oophorectomy and Tamoxifen in Premenopausal Women With Hormone Receptor-Positive Breast Cancer

Start date: January 2004
Phase: Phase 3
Study type: Interventional

This trial tests surgical oophorectomy (removal of ovaries) plus Tamoxifen, done at different times in the menstrual cycle, as adjuvant therapy for invasive breast cancer in 510 premenopausal women with Hormone Receptor-positive Breast Cancer. This study is recruiting at hospitals in Philippines, Vietnam, and Morocco.