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Breast Cancer clinical trials

View clinical trials related to Breast Cancer.

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NCT ID: NCT00893061 Completed - Breast Cancer Clinical Trials

Letrozole, Anastrozole, Exemestane, or Tamoxifen Citrate in Treating Postmenopausal Women With Breast Cancer

MNEMOSYNE
Start date: March 16, 2009
Phase: Phase 3
Study type: Interventional

RATIONALE: Estrogen can cause the growth of breast cancer cells. Aromatase inhibitors, such as letrozole, anastrozole, and exemestane, may fight breast cancer by lowering the amount of estrogen the body makes. Hormone therapy, using tamoxifen citrate, may fight breast cancer by blocking the use of estrogen by the tumor cells. It is not yet known whether aromatase inhibitors or tamoxifen citrate have less effect on memory in patients receiving treatment for breast cancer. PURPOSE: This randomized phase III trial is studying letrozole, anastrozole, or exemestane to see how they effect memory compared with tamoxifen citrate in treating postmenopausal women with breast cancer.

NCT ID: NCT00893035 Completed - Breast Cancer Clinical Trials

Evaluation of an Apoptotic Test for Predicting Late Toxicities After Radiotherapy in Breast and Prostate Cancer Patients

Start date: June 2006
Phase:
Study type: Observational

The primary objective of this study is to evaluate the prediction of late toxicity by the radiation induced CD8 T-lymphocyte apoptosis

NCT ID: NCT00892736 Completed - Breast Carcinoma Clinical Trials

Veliparib in Treating Patients With Malignant Solid Tumors That Do Not Respond to Previous Therapy

Start date: April 20, 2009
Phase: Phase 1
Study type: Interventional

This phase I trial studies the side effects and best dose of veliparib in treating patients with malignant solid tumors that do not respond to previous therapy. Veliparib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

NCT ID: NCT00892515 Completed - Breast Cancer Clinical Trials

Exercise Programs in Healthy Young Women at Increased Risk of Developing Breast Cancer

Start date: October 2008
Phase: N/A
Study type: Interventional

RATIONALE: Exercise may change the risk of developing breast cancer. It is not yet known whether low-intensity exercise or high-intensity exercise is more effective in lowering the risk of breast cancer. PURPOSE: This randomized clinical trial is studying how well exercise programs work in healthy young women at increased risk of developing breast cancer.

NCT ID: NCT00890994 Completed - Breast Cancer Clinical Trials

Molecular Breast Imaging (MBI) in Patients With Suspected Ductal Carcinoma in Situ (DCIS)

Start date: January 19, 2009
Phase: N/A
Study type: Observational

In this research study, the investigators are testing a new type of breast camera, called Molecular Breast Imaging, to see if it can find tumors in the subject's breast.

NCT ID: NCT00888589 Completed - Breast Cancer Clinical Trials

Detection of Aggressive Breast Tumors Using Tc-99m-NC100692

Start date: May 2008
Phase: N/A
Study type: Observational

The purpose of this study is to compare two types of radioactive drugs to see if they provide the same or different information about any disease that may be present in the participants breast.

NCT ID: NCT00887692 Completed - Breast Carcinoma Clinical Trials

Comparison of Set-up Reproducibility Between Prone and Supine Intensity Modulated Radiotherapy (IMRT) for the Adjuvant Treatment of Breast Carcinoma After Lumpectomy

Start date: July 2009
Phase: N/A
Study type: Interventional

10 patients will be treated alternating daily between prone and supine position for breast radiotherapy to compare set-up accuracy. Prone treatment will be given on the odds days and supine treatment on the even days.

NCT ID: NCT00887575 Completed - Breast Cancer Clinical Trials

Neoadjuvant Sunitinib With Paclitaxel/Carboplatin in Patients With Triple-Negative Breast Cancer

Start date: June 2009
Phase: Phase 1/Phase 2
Study type: Interventional

This trial will examine the combination of sunitinib plus paclitaxel and carboplatin as neoadjuvant treatment for locally advanced breast cancer.

NCT ID: NCT00887536 Completed - Breast Cancer Clinical Trials

A Clinical Trial Comparing the Combination of TC Plus Bevacizumab to TC Alone and to TAC for Women With Node-Positive or High-Risk Node-Negative, HER2-Negative Breast Cancer

Start date: May 2009
Phase: Phase 3
Study type: Interventional

The main purpose of this study is to learn if adding bevacizumab to standard treatment with chemotherapy (docetaxel, doxorubicin, and cyclophosphamide) for early stage HER2-negative breast cancer will prevent breast cancer from returning. A second purpose of this study is to learn if adding bevacizumab to treatment with chemotherapy will help women with HER2-negative breast cancer live longer. The researchers also want to learn about the side effects of the combination of drugs used in this study.

NCT ID: NCT00887523 Completed - Breast Carcinoma Clinical Trials

Trial Comparing Prone and Supine Intensity-modulated Radiotherapy (IMRT) After Breast-conserving Surgery in Patients With Large Breast Volume at High Risk for Skin Toxicity and Fibrosis

Start date: July 2009
Phase: N/A
Study type: Interventional

84 patients with a cup size C or more will be randomized to receive intensity-modulated radiotherapy in supine or prone position.