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Breast Cancer clinical trials

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NCT ID: NCT01153282 Completed - Breast Cancer Clinical Trials

Physical Functional Side Effects of Taxane Chemotherapy for Breast Cancer

Start date: June 2010
Phase:
Study type: Observational

Determine the characteristics of symptoms and functional impairment associated with chemotherapy induced peripheral neuropathy.

NCT ID: NCT01153126 Completed - Breast Cancer Clinical Trials

Moderating the Negative Impact of Abnormal Screening Mammograms

Start date: May 2010
Phase: N/A
Study type: Interventional

This project evaluates the impact of CHESS-Mammo by assessing participants' health information competence, psychological distress, and satisfaction with their doctor as measured by previously validated survey questionnaires.

NCT ID: NCT01152606 Completed - Breast Cancer Clinical Trials

A Study of Cardiac Safety in Patients With HER2 Positive Early Breast Cancer Treated With Herceptin

Start date: August 30, 2007
Phase: N/A
Study type: Observational

This is a single cohort observational safety study. All patients will be treated and monitored according to the local clinical practice. No additional procedures/patient visits in comparison with the usual clinical practice are planned for the study. Data will be collected from centre's medical records for up to 5 years or death.

NCT ID: NCT01152398 Completed - Breast Cancer Clinical Trials

A Safety and Immunology Study of a Modified Vaccinia Vaccine for HER-2(+) Breast Cancer After Adjuvant Therapy

Start date: June 2010
Phase: Phase 1
Study type: Interventional

The current trial, BNIT-BR-003, will evaluate the safety and biological activity of a fixed dose of MVA-BN®-HER2 following adjuvant chemotherapy in patients with HER-2-positive breast cancer. The intent of vaccination is to induce a combined antibody and T-cell anti-HER-2 immune response, which is intended to target HER-2-expressing tumor cells, and may induce tumor regression or slow progression of disease.

NCT ID: NCT01151488 Completed - Sarcopenia Clinical Trials

Nutrition, Exercise, and Breast Cancer Survivorship

Start date: May 2012
Phase: N/A
Study type: Interventional

The purpose of the study is to examine the effects of resistance training on the reasons (mechanisms) underlying the development of fatigue, muscle weakness and wasting (sarcopenia), and impaired physical functioning (poor balance and walking) associated with breast cancer survivorship.

NCT ID: NCT01150513 Completed - Breast Cancer Clinical Trials

Docetaxel+Carboplatin vs Epirubicin+Cyclophosphamide Followed by Docetaxel as Adjuvant Treatment in Triple-negative Breast Cancer

Start date: June 2009
Phase: Phase 2/Phase 3
Study type: Interventional

Triple-negative breast cancer (TNBC) has a relatively bad prognosis whereas there is no standard regimen. Some data showed that platins could improve the efficacy of advance TNBC. In this trial, it is the hypothesis that TP (docetaxel plus carboplatin) has a better efficacy than EC-T (epirubicin plus cyclophosphamide followed by docetaxel).

NCT ID: NCT01148875 Completed - Breast Cancer Clinical Trials

Mammography Reminders for Encouraging Women to Undergo Regular Mammography Screenings for Breast Cancer

Start date: September 2004
Phase: N/A
Study type: Observational

RATIONALE: Mammography reminders may encourage women to undergo regular mammography screenings for breast cancer. PURPOSE: This randomized clinical trial is studying three different mammography reminder interventions to compare how well they work in encouraging women to undergo regular mammography screenings for breast cancer.

NCT ID: NCT01148849 Completed - Breast Cancer Clinical Trials

Safety Study of MGAH22 in HER2-positive Carcinomas

Start date: July 2010
Phase: Phase 1
Study type: Interventional

The purpose of this study is to determine if MGAH22 is safe when given by intravenous (IV) infusion to patients with HER2-positive cancer. The study will also evaluate how long MGAH22 stays in the blood and how long it takes for it to leave the body, what is the highest dose that can safely be given, and whether it has an effect on tumors.

NCT ID: NCT01147965 Completed - Breast Cancer Clinical Trials

Active Immunotherapy CEA Vaccine in Patients With Malignancies Expressing CEA

Start date: June 2010
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to find out what effects (good and bad) that a cancer vaccine has on you and your cancer. The cancer vaccine is called Ad5 [E1-, E2b-]-CEA(6D)or ETBX-011 and is made by Etubics. This vaccine is based on a virus called an adenovirus but it has been changed to express the protein CEA that is found on some cancer cells. Therefore, the vaccine can tell the immune system to attack cancer cells which make CEA. The investigators are trying to determine whether giving this virus is safe and whether this causes a strong immune system attack on the cancer. ETBX-011 is an investigational drug.

NCT ID: NCT01147367 Completed - Breast Cancer Clinical Trials

Physical Activity, Fatigue, Sleep, and Inflammation

ABLE
Start date: August 2010
Phase: N/A
Study type: Interventional

The purpose of the study is to examine the benefits of physical activity for breast cancer survivors related to muscle strength, tiredness, and sleep quality. Also, the study will determine the potential role of inflammation in these benefits.