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Breast Cancer clinical trials

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NCT ID: NCT01264562 Completed - Breast Cancer Clinical Trials

Cognition in Breast Cancer Patients: The Impact of Cancer-related Stress

Cognicares
Start date: January 2011
Phase: N/A
Study type: Observational

The study will investigate the impact of cancer-related stress and its consequences (acute and posttraumatic stress symptoms, altered cortisol secretion) on cognitive function in breast cancer patients. The hypothesis that stress associated with the cancer diagnosis and the cancer treatment is a major cause of cognitive dysfunction in breast cancer patients shall be evaluated.

NCT ID: NCT01263613 Completed - Breast Cancer Clinical Trials

Feasibility Study of Biomarkers of Response to Neoadjuvant Paclitaxel in Locally Advanced Breast Cancer

Start date: December 2010
Phase: Early Phase 1
Study type: Interventional

The purpose of this study is to determine if the investigators are able to locate and measure certain characteristics in breast cancer tumors that have been treated with paclitaxel that may correlate to how well the cancer will respond to the chemotherapy.

NCT ID: NCT01262716 Completed - Breast Cancer Clinical Trials

A Novel Therapy for the Treatment of Chest Wall Progression of Breast Cancer

Start date: December 2010
Phase: N/A
Study type: Observational

This study will assess safety and ergonomics/engineering design of a novel cancer treatment, Continuous Low Irradiance Photodynamic therapy (CLIPT). We will assess the effects on primary and metastatic tumors involving the skin, in particular to improve the functionality, efficiency and wearability of the light delivery device (LDD) as well as the overall treatment in subjects with chest wall recurrences of breast cancer. An ongoing study (IRB# 8227), sponsored by a Susan G. Komen Breast Cancer Foundation grant, using a 1st generation LDD device has evaluated and determined a dose-limiting toxicity of CLIPT for subjects with chest wall recurrences of breast cancer. A Diomed laser will be the device used in this study. The Diomed laser will deliver 630 nm (red spectrum) light through a Fiber Optic Patch. The Fiber Optic patch will be compatible with the laser, delivering light to a designated region on the patient's skin.

NCT ID: NCT01262027 Completed - Breast Cancer Clinical Trials

TKI258 for Metastatic Inflammatory Breast Cancer Patients

Start date: January 27, 2012
Phase: Phase 2
Study type: Interventional

The goal of this clinical research study is to learn if dovitinib can help to control inflammatory breast cancer. The safety of this drug will also be studied.

NCT ID: NCT01256567 Completed - Breast Cancer Clinical Trials

A Study of Ramucirumab (IMC-1121B) in Participants With Breast Cancer

Start date: December 2010
Phase: Phase 1
Study type: Interventional

The primary objective of this study is to investigate the safety and tolerability of the anti-VEGFR-2 monoclonal antibody ramucirumab drug product in combination with docetaxel in Japanese participants with metastatic, or locally advanced breast cancer, with the aim of confirming the recommended dose of ramucirumab drug product (DP) in combination with docetaxel.

NCT ID: NCT01256528 Completed - Breast Cancer Clinical Trials

Delayed-Delayed Breast Reconstruction

Start date: December 2010
Phase: N/A
Study type: Interventional

The goal of this clinical research study is to learn if delayed-delayed breast reconstruction in women who require post-mastectomy radiation therapy will improve cosmetic outcomes and result in fewer complications compared to the standard approach (reconstruction that is not started until radiation treatment is completed).

NCT ID: NCT01256008 Completed - Breast Cancer Clinical Trials

Intervention Study of Depression in Breast Cancer Patients

Start date: December 2010
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the efficacy of cognitive-behavioral therapy on depression and anxiety in breast cancer patients.

NCT ID: NCT01254526 Completed - Breast Cancer Clinical Trials

Study of the Safety and Pharmacology of GDC-0980 in Combination With Paclitaxel With or Without Bevacizumab in Patients With Locally Recurrent or Metastatic Breast Cancer

Start date: December 2010
Phase: Phase 1
Study type: Interventional

This is an open-label, multicenter, Phase Ib dose-escalation study to assess the safety, tolerability, and pharmacokinetics of GDC-0980 administered with taxane-based chemotherapy regimens utilized in patients with locally recurrent or metastatic breast cancer.

NCT ID: NCT01252290 Completed - Breast Cancer Clinical Trials

Breast Cancer Risk Biomarkers in Postmenopausal Women

Start date: November 2010
Phase: Phase 2
Study type: Interventional

This study is designed to gather information on how the prescription drug Lovaza™ which contains omega-3 fatty acids, affects blood and tissue risk biomarkers for breast cancer. This drug is currently approved by the FDA for reducing blood levels of triglycerides.

NCT ID: NCT01252277 Completed - Breast Cancer Clinical Trials

Breast Cancer Risk Biomarkers in Premenopausal Women

Start date: November 2010
Phase: Phase 2
Study type: Interventional

This study is designed to gather information on how the prescription drug Lovaza™ which contains omega-3 fatty acids, affects blood and tissue risk biomarkers for breast cancer. This drug is currently approved by the FDA for reducing blood levels of triglycerides.