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Clinical Trial Summary

Multivessel TALENT is a prospective, randomized, multi-center study comparing clinical outcomes between SUPRAFLEX Cruz and SYNERGY in approximately 1550 patients with de-novo three vessel disease undergoing percutaneous coronary intervention (PCI). Patients will be treated according to "state of art PCI"; not only treatment strategies based on the latest ESC guideline, such as SYNTAX Score II recommendation, Heart Team discussion, post-procedure intravascular imaging optimization, cholesterol reduction by statin or PCSK-9 inhibitor, but also exploratory treatment strategies based on the latest evidence, such as physiological assessment using quantitative flow ratio and prasugrel monotherapy following 1-month dual antiplatelet therapy after PCI.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT04390672
Study type Interventional
Source National University of Ireland, Galway, Ireland
Contact Patrick W. Serruys, MD, PhD
Phone +353 91459047
Email multivtcoord@nuigalway.ie
Status Recruiting
Phase N/A
Start date September 22, 2020
Completion date August 2026

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