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Acute Decompensated Heart Failure clinical trials

View clinical trials related to Acute Decompensated Heart Failure.

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NCT ID: NCT03695120 Not yet recruiting - Clinical trials for Acute Decompensated Heart Failure

RAAS Optimization for Acute CHF Patients

ROAD-HF
Start date: October 2018
Phase: N/A
Study type: Interventional

Holding ACEI/ARBs during initial 72 hours of admission with acute decompensated heart failure may help preserve renal function with a lesser decline in GFR. This treatment modification will also allow the option of aggressive diuresis in volume overloaded CHF patients which should result in a lesser decline of AKI, length of stay, readmission rates, and cost associated with CHF treatment.

NCT ID: NCT03555123 Not yet recruiting - Clinical trials for Acute Decompensated Heart Failure

Evaluate the Efficacy and Safety of Short-term Administration of SIMDAX

Start date: June 30, 2018
Phase: Phase 3
Study type: Interventional

A randomized, double-blind, Multicenter, parallel, placebo-controlled study

NCT ID: NCT03505788 Not yet recruiting - Clinical trials for Acute Decompensated Heart Failure

Acetazolamide in Decompensated Heart Failure With Volume OveRload (ADVOR)

Advor
Start date: October 1, 2018
Phase: Phase 4
Study type: Interventional

This clinical research study is being conducted in multiple hospitals in Belgium and approximately 519 patients with acute decompensated heart failure are expected to participate. Large-scale research shows that 90% of the physicians treat volume overload with high doses of loop diuretics. However, there is not a lot of scientific data available regarding the optimal doses of these diuretic medications. In addition, it is observed that a lot of people, treated with these drugs, are being readmitted to the hospital due to a new episode of heart failure. The hypothesis of this study is that the volume overload could be better treated when patients receive a combination of different types of diuretics. Additionally, the total dose of the administrated diuretics might be lower this way.

NCT ID: NCT03246035 Not yet recruiting - Heart Failure Clinical Trials

Reducing Readmission for Frail Elderly Patients With Decompensated Heart Failure

HFF-ED
Start date: March 2018
Phase: N/A
Study type: Interventional

A randomized study designed to determine whether telephone based interventions can prevent return hospital visits for elderly and frail patients with acute symptoms of heart failure. Specifically, the intervention will improve patients ability to monitor and address self care of heart failure at home.