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Varicose Veins clinical trials

View clinical trials related to Varicose Veins.

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NCT ID: NCT04908527 Completed - Vein, Varicose Clinical Trials

Effect of Walking to the Operating Room on Preoperative Anxiety

Start date: May 15, 2019
Phase: N/A
Study type: Interventional

The operating room environment can be a source of anxiety for the patient, including in the context of outpatient surgery for which anxiolytic medication is rarely used. This anxiety-induced effect can be reinforced by the patient's lack of active participation. Some studies have already shown the feasibility of patient walking to the operating room (OR) and advantages this approach(Kojima and Ina 2002; Lack 2016; Nagraj et al. 2006). Moreover, recovery room complications and pain have also been shown to be greater after varicose vein surgery in patients with significant preoperative anxiety (Scavee et al. 2016). Therefore, the investigators decided to test the effects of walking to OR for patients admitted for outpatient surgery for varicose vein surgery.

NCT ID: NCT04828369 Completed - Liver Cirrhosis Clinical Trials

Efficacy and Safety of EUS-Guided Therapy Versus BRTO for Gastric Varices With Shunt

Start date: October 1, 2020
Phase:
Study type: Observational

This study is a retrospective, multi-center and observational clinical study. Renmin Hospital of Wuhan University, Beijing Friendship Hospital, Capital Medical University, The fifth medical center of PLA General Hospital, Zhongshan Hospital, Fudan University, Shanghai, Nanjing Drum Tower Hospital affiliated Nanjing University Medical School and Xiangyang Central Hospital will participate in the study. Investigators would like to provide evidence-based medical evidence by evaluating and comparing the efficacy and safety of endoscopic ultrasound (EUS)-guided coil embolization combined with endoscopic cyanoacrylate injection and balloon-occluded retrograde transvenous obliteration (BRTO) in the treatment of gastric varices (GV) with spontaneous portosystemic shunt (SPSS). Between January 2014 and December 2020, patients with GV secondary to portal hypertension admitted to a tertiary medical center, are enrolled consecutively according to the following criteria: (1) age≥18 years; (2)endoscopic examination confirms the presence of GV; (3) CTA of the portal system and EUS revealed the presence of SPSS, the diameter was between 5 mm to 15 mm; (4) treatment with EUS-guided coil combined with endoscopic cyanoacrylate injection or BRTO. Exclusion criteria are as follows: (1)malignant tumors; (2) hepatic encephalopathy, hepatorenal syndrome or multiple organ failure; (3) previously received esophagus or stomach surgery; (4) pregnant. Investigators will collect patients' data of baseline character, treatment, postoperative and follow-up. All patients will be followed up until the progress of the disease or the end of the study. And rebleeding, ectopic embolism, survival, and sequential treatment will be recorded during the follow-up period. The primary endpoint are five-day rebleeding rate and six-week mortality rate. The secondary endpoint are: technical success rate, incidence of ectopic embolism, eradication of GV, one-year rebleeding rate, one-year mortality rate, and cost-effectiveness ratio. All data and information use SPSS statistical software to complete all statistical analysis.

NCT ID: NCT04823780 Completed - Liver Cirrhosis Clinical Trials

The Effects of Early Enteral Nutrition on Endoscopic Therapy of Esophagogastric Varices in Liver Cirrhosis

Start date: September 1, 2020
Phase:
Study type: Observational

The purpose of this study was to evaluate the safety of early enteral nutrition on endoscopic therapy of esophagogastric varices in Liver Cirrhosis ,and to assess the impact of different eating times on patients, so as to determine the best time for patients to obtain nutrition after surgery.

NCT ID: NCT04794712 Not yet recruiting - Clinical trials for Chronic Venous Insufficiency

Evaluation of Pain Associated With Chronic Venous Insufficiency

Start date: May 15, 2021
Phase:
Study type: Observational [Patient Registry]

Chronic venous insufficiency occurs when your leg veins don't allow blood to flow back up to your heart. Normally, the valves in your veins make sure that blood flows toward your heart. But when these valves don't work well, blood can also flow backwards. This can cause blood to collect (pool) in the legs. Chronic venous disease is a highly prevalent condition in the general population, and it has a significant impact on quality of life. While it is usually manifested by obvious signs, such as varicose veins and venous ulcers, other symptoms of the disease are less specific. Among the other symptoms, which include heaviness, swelling, muscle cramps and restless legs, pain is the symptom that most frequently compels CVeD patients to seek medical aid. However, there is a substantial discrepancy between pain severity and clinically detectable signs of CVeD, questioned by several opposing studies. Further evaluation is needed to clarify this subject, and to analyse whether pain development predicts objective tool to evaluate pain by dosflexin exercise pre surgery and post and measure the severity of pain by heat stimulation . General management of CVeD starts with advising lifestyle . pain in chronic venous insufficiency it will measure before and after treatment by using contact heat evoked potential (CHEPS) and visual dialog scale ( VAS ) to estimate the pain intensity the severity of the pain before the patient do exercise before three moths of leaser endovenous ablation procedure . 2-photo-plethysomography Non invasive technique , pp sensor emit infrared light detects changes in reflection from epiderma layer . Vessels full of blood reflect 10 times less than without blood . On dorsiflexion - pressure drops, increasing reflection in the measuring window Venous assessment the venous refill time, is shorter and typically less than 20 s

NCT ID: NCT04726124 Active, not recruiting - Clinical trials for Varicose Veins of Lower Limb

MicrOwave and laSer ablaTion Study (MOST Study)

MOST
Start date: January 26, 2021
Phase: N/A
Study type: Interventional

To validate the safety and efficacy of microwave versus laser ablation of the great saphenous vein in patients with varicose veins of lower extremities

NCT ID: NCT04720027 Completed - Clinical trials for Varicose Veins of Lower Limb

Long Term Study of 3 Radiofrequency Devices

3RF-5Years
Start date: June 10, 2021
Phase:
Study type: Observational

To establish which of the radiofrequency venous ablation modalities studied in the original 3RF study (Venefit (Closurefast), vs. Radiofrequency induced Thermal Therapy vs. Endovenous Radiofrequency) is most effective in relieving patients' symptoms and signs from varicose veins disease, and in maintaining absence of reflux in the treated vein segment (of the great saphenous vein (GSV)) 5 years following surgery.

NCT ID: NCT04692805 Recruiting - Portal Hypertension Clinical Trials

EUS-guided PSE in Combination With EUS-guided Treatment of Varices for Patients With Portal Hypertension

Start date: January 5, 2021
Phase: N/A
Study type: Interventional

This study aims to evaluate the efficiency of EUS-guided combination therapy (EUS-guided PSE + EUS-guided treatment of varices) to EUS-guided treatment of varices alone in cirrhotic patients with portal hypertension who have developed gastroesophageal variceal hemorrhage and accompanied with hypersplenism.

NCT ID: NCT04671641 Active, not recruiting - Varicose Veins Clinical Trials

Endovenous Radiofrequency Ablation Closure System in the Treatment of Varicose Veins

Start date: April 1, 2021
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to evaluate the effectiveness and safety of the endovenous radiofrequency ablation closure system produced by Suzhou Hengrui Hongyuan Medical Technology Co., Ltd. for the treatment of varicose veins.

NCT ID: NCT04658901 Completed - Clinical trials for Varicose Veins of Lower Limb

ACOART RF CLOSURE:Radiofrequency for Varicose Veins of Lower Extremity in China

Start date: May 18, 2021
Phase: N/A
Study type: Interventional

The purpose of the RCT trial is to determine whether endovenous radiofrequency closure catheter and endovenous radiofrequency closure generator is not inferior to ClosureFast™ and ClosureRFG™ in treating varicose veins of lower extremity.

NCT ID: NCT04655417 Recruiting - Pain Clinical Trials

is Ultrasound-guided Foam Sclerotherapy a Cost-effective Alternate for Treatment of Varicose Veins?

Start date: February 21, 2020
Phase: Early Phase 1
Study type: Interventional

. It is the aim of this paper is to discuss our experience of foam sclerotherapy for varicose veins atour hospital