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Varicose Veins clinical trials

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NCT ID: NCT04645771 Recruiting - Clinical trials for Varicose Veins of Lower Limb

Safety and Efficacy Study of Endovenous Microwave Ablation for Treatment of Varicose Veins

EMINENCE
Start date: February 4, 2021
Phase: N/A
Study type: Interventional

The purpose of this study was to evaluate the efficacy and safety of microwave ablation catheter in the treatment of varicose veins in lower extremities,meanwhile, to compare the quality of subjects'lives before and after treatment.

NCT ID: NCT04546750 Recruiting - Clinical trials for Venous Insufficiency

Prospective Cohort Study for Varicose Veins Incidence and Natural Course

VINCI
Start date: September 1, 2020
Phase:
Study type: Observational

A prospective study of individuals without varicose veins and who have primary varicose veins to assess the morbidity, risk factors and natural course of chronic lower limb vein disease.

NCT ID: NCT04537052 Not yet recruiting - Clinical trials for Primary Varicose Veins

A New Method for Treatment of Deep Venous Insufficiency: Early Results of Vein Restoration Treatment(VRT)

Start date: September 27, 2020
Phase: N/A
Study type: Interventional

To present the 9. months clinical results of percutaneous Ven Restoration Therapy (VRT), a new method in the treatment of primary femoral vein insufficiency.Twenty four patients diagnosed with isolated primary femoral vein insufficiency between January 2020 and December 2020 were included in the study. Before the procedure, junctional femoral vein diameters and reflux times were measured. CEAP classification and Venous clinical severity scores (VCSS) were recorded. Chronic Venous Insufficiency Questionnaire (CIVIQ-20) were also recorded. Then, VRT was applied percutaneously to the anterior and posterior of the femoral veins of the patients, and the diameter of the femoral vein was narrowed and valve coaptation was achieved. After the procedure, vein diameters and reflux times were measured again. All parameters were reevaluated by calling patients for control at 1.,3., 6. and 9. months.

NCT ID: NCT04527666 Not yet recruiting - Clinical trials for Myeloproliferative Neoplasm

Anticoagulation in Gastroesophageal Varices and JAK2 Mutation

Start date: October 1, 2020
Phase:
Study type: Observational

Myeloproliferative neoplasms (MPNs), including polycythemia vera, essential thrombocythemia, and primary myelofibrosis, may lead to gastroesophageal varices. The quality of life, morbidity, and mortality of MPN patients mainly depend on disease-related symptoms, thromboembolic and hemorrhagic complications. Previous studies have shown that JAK2 V617F has a prominent role in vascular risk and MPN-associated gastroesophageal varices. The aim of this study is to evaluate the efficacy of anticoagulation in patients with JAK2 mutation and gastroesophageal varices.

NCT ID: NCT04526626 Active, not recruiting - Clinical trials for Varicose Veins of Lower Limb

Endovenous RFA Versus Ligation and Striping for Varicose Veins

Start date: February 1, 2020
Phase: N/A
Study type: Interventional

Varicose vein is a common chronic disease affecting patient's quality of life. High ligation and stripping of the long saphenous vein is the traditional operation for varicose vein. The radiofrequency ablation (RFA) device used for treatment of varicose vein has been available in China since 2014. There are few studies comparing RFA and stripping in the treatment of varicose vein. This study was to investigate the outcomes of RFA and stripping for varicose vein. Patients with varicose veins will be prospectively allocated to RFA group and stripping group. Ultrasound follow-up will be performed to assess recanalization of long saphenous vein at 1 month, 3, 6 and 12 months. Recurrence of varicose vein and improvement of symptoms will also be evaluated. The primary endpoints are technical success, complications and recurrence of varicose vein. Secondary endpoints are duration of operation, blood loss, recovery time, venous clinical severity score, and medical cost. The treatment outcomes will be compared between the RFA group and stripping group. RFA is comparable to traditional stripping in the treatment of varicose vein, however, it is associated quick recovery, lower incidence of complications and higher medical cost.

NCT ID: NCT04525768 Not yet recruiting - Portal Hypertension Clinical Trials

Gastroesophageal Varices in Cavernoma

Start date: October 1, 2020
Phase:
Study type: Observational

Myeloproliferative neoplasms (MPNs), including polycythemia vera, essential thrombocythemia, and primary myelofibrosis, may lead to gastroesophageal varices. The quality of life, morbidity, and mortality of MPN patients mainly depend on disease-related symptoms, thromboembolic and hemorrhagic complications. Previous studies have shown that JAK2 V617F has a prominent role in vascular risk and MPN-associated gastroesophageal varices. Portal vein thrombosis and portal cavernoma frequently occur in the MPN population and the management of gastroesophageal varices in these patients are sometimes technically difficult. The aim of this study is to investigate the the characteristics of patients with gastroesophageal varices and portal caver cavernoma with or without JAK2 mutation.

NCT ID: NCT04524793 Active, not recruiting - Vascular Diseases Clinical Trials

Efficacy and Safety of Endovenous Microwave Ablations for Treatment of Varicose Veins in Singapore

MAESTRO
Start date: May 9, 2020
Phase: N/A
Study type: Interventional

The purpose of this study is to assess change in patient's symptoms before and after Endovenous Microwave Ablation (EMA) as treatment for varicose veins. At the same time, it is to evaluate the effectiveness of EMA and its treatment outcomes over a period of 1 year.

NCT ID: NCT04487314 Recruiting - Clinical trials for Varicose Veins of Lower Limb

Registry for Chronic Venous Disease Incidence and Natural Course

RRCVD
Start date: August 20, 2020
Phase:
Study type: Observational

A prospective cohort study of patients with primary varicose veins to assess the morbidity, risk factors and development of chronic lower limb vein disease.

NCT ID: NCT04479956 Recruiting - Varicose Veins Clinical Trials

Microwave Venous Ablation in Comparison to Radiofrequency Ablation, Laser Ablation and Surgical Ligation in Management of Great Saphenous Vein Incompetence

Start date: June 18, 2020
Phase: N/A
Study type: Interventional

The authors will aim to compare microwave therapy with other lines of management radio-frequency ablation, Laser ablation and surgical ligation; regarding time to recurrence rate, ulcer-free time, and health-related quality of life. In a randomized controlled study,The study will be conducted at the department of vascular surgery in Mansoura university hospitals

NCT ID: NCT04441957 Recruiting - Surgery Clinical Trials

MechanO-Chemical Ablation Versus CompreSSion

MOCASS
Start date: January 1, 2018
Phase:
Study type: Observational

This study will be looking at the effect of Endovenous Mechano-Chemical Ablation (MOCA) in addition to multilayer elastic compression bandaging vs multilayer elastic compression bandaging only in patients with incompetent great saphenous vein (GSV) and venous ulcers (VU's).