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Varicose Veins clinical trials

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NCT ID: NCT06290973 Completed - Quality of Life Clinical Trials

Quality of Life and Health Perception After Surgery of Varicose Veins

Start date: January 2, 2023
Phase:
Study type: Observational

The aim of this study is to analyze changes in health perception and quality of life in patients after surgery for varicose veins using clinical score VCSS and QoL scores SF12 as general health questionary and Veines QoL/Sym as disease specific questionary.

NCT ID: NCT06271798 Recruiting - Varicose Veins Clinical Trials

Effect Of Resistive Exercises Versus Aerobic Exercises On Varicose Veins In Postmenopausal Women

Start date: February 20, 2024
Phase: N/A
Study type: Interventional

The purpose of this study will be to determine the effect of resistive exercises on varicose veins in postmenopausal women, the effect of aerobic exercise on varicose veins in postmenopausal women and to compare between the effect of resistive exercise versus aerobic exercise on varicose veins in post menopausal women.

NCT ID: NCT06192472 Completed - Varicose Veins Clinical Trials

Investigation Into the Pathophysiology and Treatment of Varicose Veins

Start date: April 2013
Phase: N/A
Study type: Interventional

Chemical sclerotherapy is commonly used to treat varicose veins which affect superficial veins in the leg. Sclerotherapy is injected directly into veins where it causes damage to the vein wall. If sufficient damage occurs, the vein is transformed into a fibrous cord which does not re-open. This study will investigate the structural changes caused to the wall of veins following injection with sclerotherapy ex vivo. Vein samples will be obtained from the Whiteley Clinic in Guildford from patients undergoing phlebectomy operations. These will then be injected with sclerotherapy and the extent of damage will be investigated. Samples will also be used for laboratory analysis into the pathophysiology of varicose veins.

NCT ID: NCT06175546 Enrolling by invitation - Clinical trials for Chronic Venous Insufficiency

Daily Duration of Compression Treatment in Patients With Symptomatic Chronic Venous Disease

Start date: February 15, 2023
Phase: N/A
Study type: Interventional

Aim of study is to investigate the optimal duration and daily regimen of compression treatment in patients with chronic venous disease

NCT ID: NCT06168058 Not yet recruiting - Pelvic Pain Clinical Trials

Trial of Ovarian Vein and Pelvic Vein Embolization in Women With Chronic Pelvic Pain and Pelvic Varices

EMBOLIZE
Start date: March 2024
Phase: N/A
Study type: Interventional

The purpose of this study is to see if a randomized controlled trial of ovarian vein and pelvic vein embolization versus venography alone could determine outcomes for women with chronic pelvic pain and pelvic varicose veins. The data gathered will assist in addressing changes in quality of life in patients who have ovarian/pelvic vein embolization versus no embolization.

NCT ID: NCT06124664 Recruiting - Clinical trials for Varicose Veins of Lower Limb

Study of Venous Outflow From the Lower Limbs in Patients With Pelvic Varicosities

Start date: May 4, 2023
Phase:
Study type: Observational

Compression therapy is basic treatment for chronic venous disease (CVD) of the lower limbs. Numerous studies have demonstrated the efficacy and safety of compression therapy in relieving symptoms such as pain, venous edema, leg heaviness and fatigue, as well as accelerating the healing of venous ulcers. It has been established that сompression therapy is indicated for patients with both minimally expressed manifestations of CVD and severe forms of the disease. At the same only one study has been conducted to assess the correction of venous outflow from the lower limbs and pelvis in patients with pelvic varicose vein (PVV) and pelvic congestion syndrome (PCS). However, the incidence of this pathology ranges from 15 to 30% in the female population. The cost to the healthcare system of treating these patients in the United States exceeds $2 billion. To date, the options and indications for compression therapy in patients with concomitant PVV and CVD have not been defined. The rational use of compression in this cohort of patients may contribute to the improvement of effective conservative treatment. In addition, inappropriate prescription of compression to patients with pelvic venous disease (which can be observed in real clinical practice) may discredit this simple, effective and safe therapeutic method. In addition, the research devoted to the problem of compression treatment of PVV will contribute to the development of new special compression products aimed at accelerating venous outflow from the pelvic organs. It can be assumed that this will serve as a stimulus for obtaining new data on the therapeutic effects of compression and create conditions for the creation of new technological directions in the production of compression knitwear.

NCT ID: NCT06082219 Not yet recruiting - Esophageal Varices Clinical Trials

Ulcer Bleeding After Band Ligation of Esophageal Varices

Start date: January 1, 2024
Phase:
Study type: Observational

Primary Outcomes: assessment of incidence , risk factors and prognosis of post-banding ulcer bleeding following EVL in patients with liver cirrhosis. Secondary Outcomes: minimize post-banding ulcer bleeding

NCT ID: NCT06017102 Recruiting - Esophageal Varices Clinical Trials

Wired Magnetically Assisted Capsule Endoscopy and Esophageal Varices

Start date: September 5, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to compare the safeness and effectiveness of traditional esophagogastroduodenoscope (EGD) and wired magnetically assisted capsule endoscopy (MACE) in the diagnosis of esophageal varices in biliary atresia (BA) patients. The main questions it aims to answer are: - Subjects who do wired magnetically assisted capsule endoscopy do not need to open the mouths during the process, this study also want to know whether wired magnetically assisted capsule endoscopy can reduce the generation of droplets. - Diagnostic accuracy between traditional esophagogastroduodenoscope and wired magnetically assisted capsule endoscopy in biliary atresia patients with esophageal varices. Participants will do either traditional esophagogastroduodenoscope or wired magnetically assisted capsule endoscopy.

NCT ID: NCT05979935 Active, not recruiting - Clinical trials for Esophageal and Gastric Varices

Prediction of Esophageal Varices in Liver Cirrhosis Using Tongue Bioinformatics

Start date: July 1, 2023
Phase:
Study type: Observational [Patient Registry]

The goal of this observational study is to compare the tongue bioinformatics of high-risk and low-risk patients with esophageal varices due to liver cirrhosis. The main question of this study is to explore whether there exists a relationship between the degree of esophageal varices and tongue bioinformatics in liver cirrhosis. it aims to answer 2 questions as below: question 1: If these is a significant difference in tongue bioinformatics between patients in liver cirrhosis with high-risk and low-risk of esophageal varices. Question 2; If tongue bioinformatics can be used as a diagnostic basic for testing esophageal varices in liver cirrhosis. Firstly, participants will be divided into two groups according to their degree of esophageal varices from electronic gastroscopy report and CT scan report including high-risk group and low-risk group. Secondly, participants will be asked to show their tongue, including the surface and sublingual veins of tongue, and the tongue images of each participants will be collected by researchers via camera. After finishing tongue image collection, participants will receive a professional tongue diagnosis report in Traditional Chinese Medicine and health suggestion.

NCT ID: NCT05978986 Recruiting - Clinical trials for Varicose Veins of Lower Limb

Efficiency of Determining the Clinical Class of Chronic Venous Disorders by Artificial Intelligence

IVENUS
Start date: August 25, 2023
Phase: N/A
Study type: Interventional

Purpose: To evaluate the sensitivity and specificity of the method for determining the clinical class of chronic venous diseases using the Ivenus application (within C0-C2 according to CEAP). Materials and methods: Patients who applied to several phlebology clinics for an initial consultation are consistently included in a multicenter prospective study. At the appointment, a doctor with at least 5 years of experience takes photographs of the lower extremities and uploads them to the IVENUS application, which automatically determines the clinical class according to CEAP, without showing the results to the surgeon (blinding). Further, the doctor independently determines the clinical class according to CEAP and enters the data into the register. The object of the study is a photograph of a certain area of the lower limb.