Type 2 Diabetes Clinical Trial
Official title:
Mechanisms of Type 2 Diabetes Improvement, Besides Weightloss After Gastric Bypass
Proof of concept, of RYGBP and its capabilities to cure type 2 diabetes (DM 2) and sleep
apnea has already been recognized in the reports on weight loss surgery.
The investigators project aims to prove that RYGBP also recovers the beta cell function
(BCF) Clamp tests, the gold standard for testing IS and BCF, will be performed preoperative
and early postoperatively.
Aims & methodology:
Analysis of the short-term effect of gastric bypass and sleeve gastrectomy on insulin
sensitivity and beta cell function.
Preoperative baseline insulin sensitivity and beta cell function will be assessed with
euglycemic and hyperglycemic clamp tests. These results will be compared with the results of
the same tests carried out 3 weeks postoperative.
To determine if the duodenal exclusion is causing this effect. The results of the clamp
tests 3 weeks postoperative will be compared
n/a
Observational Model: Case Control, Time Perspective: Prospective
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