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Thoracotomy clinical trials

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NCT ID: NCT04242160 Completed - Trauma Clinical Trials

Comparison of Two Resuscitative Thoracotomy Techniques

Start date: November 19, 2018
Phase: N/A
Study type: Interventional

Resuscitative thoracotomy (RT) is a life saving procedure for patients who have suffered cardiac arrest or are at significant risk of cardiac arrest following significant trauma. The procedure is ideally performed by a surgeon, but in some circumstance must be performed by non-surgical specialists such as Emergency Medicine physicians. The purpose of this study was to evaluate the optimal RT technique taught to non-surgical specialists in an educational human cadaver lab. The objective was to compare time to successful completion of two different RT techniques; (1) Left Anterolateral Thoracotomy (LAT) and (2) Modified Clamshell Thoracotomy (MCT). The investigators hypothesized that the non-surgical specialist time to successful completion for the MCT would be shorter than for the LAT.

NCT ID: NCT04220697 Recruiting - Hyperalgesia Clinical Trials

Central Sensitisation and Postoperative Pain

Start date: January 29, 2020
Phase: N/A
Study type: Interventional

One out of 10 patients undergoing surgery develops persistent post-surgical pain (PPSP). Unfortunately, available therapies for treating this pain have limited success. It is therefore of great importance to find strategies to prevent PPSP. The goal of this project is to find new screening tools that identify patients that are at risk for developing PPSP. Tissue injury and inflammation following surgery increase the excitability of spinal nociceptive neurons ("central sensitisation", CS) with pain hypersensitivity as consequence. It is thought that CS plays an important role in persistent pain. The first objective of this project is to assess in human patients if the propensity to develop CS manifested as secondary hyperalgesia before surgery is predictive for PPSP. In addition, we will test if the frequency content of the resting-state EEG reflecting the initial state of the brain will be related to the propensity for developing CS and to the presence of PPSP at two months after surgery.

NCT ID: NCT04193241 Recruiting - Pleural Effusion Clinical Trials

Suturing With U-Technique Versus Un-Reapproximated Wound Edges During Removal of Closed Thoracostomy Tube Drain

SUTURE
Start date: January 2, 2020
Phase: N/A
Study type: Interventional

The study will be carried out by the principal investigator and his team at the Division of Cardiovascular and Thoracic Surgery of the Department of Surgery, College of Medicine, University of Ibadan and the University College Hospital, Ibadan (UCH), which is the Teaching Hospital of the Medical College.The study sets out to prospectively compare the early and long-term outcomes between the use of purse-string (suturing U-technique) and Un-reapproximated thoracostomy wound edges (Occlusive adhesive-absorbent dressing application) at the time of removal of thoracostomy tube drain in patients who have had chest tube insertion.

NCT ID: NCT03868917 Recruiting - Thoracotomy Clinical Trials

Ultrasound-guided Approach Combined With Pressure Measurement Technique to Thoracic Paravertebral Block

Start date: January 2, 2019
Phase: N/A
Study type: Interventional

Posterolateral thoracotomies are among the most painful procedures of surgery and may cause severe postoperative chest pain and impaired respiratory performance. Paravertebral block (PVB) is an established method of administering postoperative analgesia for thoracic procedures. PVB blocks the somatic and sympathetic nervous systems and is placed by injecting a local anesthetic (LA) into the paravertebral space where the nerve and its branches are located after exiting the intervertebral foramen. But previous study showed 5-10% of failure rate in PVB using ultrasound machine. Pressure measurement during needle advancement could improve reliability of correct needle placement. When the needle tip reaches paravertebral space, there is a sudden lowering of pressures due to respiratory cycle. Therefore, sensitivity and specificity could be improved and correct needle placement become objective and reproducible when PVB using ultrasound is combined with pressure measurement during needle advancement.

NCT ID: NCT03839160 Completed - Anesthesia Clinical Trials

The Efficacy of Serratus Anterior Plane Block (ESAPB) for Thoracotomy: a Prospective Study

Start date: December 1, 2019
Phase: N/A
Study type: Interventional

Thoracotomy is considered the most painful surgical procedure. Ultrasound-guided serratus anterior plane block (SAPB) is a relatively new truncal block method treating thoracotomy pain. In this study, investigators aim to ascertain the efficacy of SAPB in thoracotomy.

NCT ID: NCT03650335 Recruiting - Thoracotomy Clinical Trials

Effect of Bupivacaine in Ultrasound-guided Erector Spinae Plane

Start date: February 15, 2019
Phase:
Study type: Observational

To investigate the effect of two different volumes of bupivacaine 0.25% used in ultrasound-guided erector spinae plane (ESP) block on dermatome spread and postoperative analgesia in patients undergoing unilateral thoracotomy

NCT ID: NCT03281213 Completed - Postoperative Pain Clinical Trials

Acute Postthoracotomy Pain - Impact of Gender

Start date: July 1, 2010
Phase: N/A
Study type: Observational

Adequate analgesia in thoracic surgery is essential to prevent severe postoperative complications, especially respiratory problems. Current knowledge about gender-related differences in pain states generally more frequent and intense pain and more demand for analgesics in women. Results about postsurgical pain in particular are very inconclusive. The investigators tried to find out if gender has an influence on postthoracotomy pain and analgesics requirement.

NCT ID: NCT02073760 Completed - Sepsis Clinical Trials

Optimizing Prevention of Healthcare-Acquired Infections After Cardiac Surgery (HAI)_2

Start date: June 2014
Phase:
Study type: Observational

The investigators will conduct qualitative interviews of hospital personnel regarding HAI prevention practices, and use coded data from these interviews to assist in developing standardized practices.

NCT ID: NCT01698203 Completed - Pain Clinical Trials

Continuous Wound Catheter Analgesia Associated With Intravenous Morphine PCA After Thoracotomy

Start date: October 14, 2012
Phase: Phase 4
Study type: Interventional

Objective: Epidural analgesia is the gold standard for post-thoracotomy pain relief but is contraindicated in certain patients. An alternative is continuous wound catheter analgesia. We will investigate whether ropivacaine, administered through a wound catheter placed by the surgeon, will reduce postoperative pain. Methods: In a randomized double-blind study, adult patients with a wound catheter placed by the thoracic surgeon after thoracotomy will be randomly assigned to receive through this catheter, either a 0.1 mL/kg bolus of 0.75% ropivacaine, followed by a continuous infusion of 0.2% ropivacaine at 10 mL/h for 48 h, or saline at the same scheme of administration. Patients will also benefit from patient-controlled analgesia with intravenous morphine (bolus 1 mg, lockout time 7 min), paracetamol, and nefopam. The primary endpoint will be total morphine consumption. Secondary endpoints will be pain intensity on a visual analog scale at rest and on coughing and side effects during the first 48 postoperative hours. Surgeons, anesthesiologists, and all the nurses and caring staff involved in this study will be blinded. Solutions of saline and ropivacaine will be prepared identically by the central pharmacy, without any possible identification of the product.

NCT ID: NCT01274871 Completed - Chronic Pain Clinical Trials

Sensory Changes From Chest Drains

Start date: December 2009
Phase: N/A
Study type: Observational

Does chest drains contribute to the post thoracotomy pain syndrome