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Thoracotomy clinical trials

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NCT ID: NCT06330168 Recruiting - Thoracotomy Clinical Trials

Paravertebral Calcitonin in Thoracotomy

Start date: March 28, 2024
Phase: N/A
Study type: Interventional

This prospective randomized double-blinded controlled study will be conducted to evaluate the effect of adding calcitonin to bupivacaine in thoracic paravertebral block for patients undergoing thoracotomy.

NCT ID: NCT05700357 Recruiting - Acute Pain Clinical Trials

Different Local Anesthetic Volumes for TPVB in Post-thoracotomy Analgesia

Start date: December 28, 2022
Phase: N/A
Study type: Interventional

Thoracotomy is one of the most painful operations known. Therefore, it causes severe acute pain. If pain is not controlled, it increases the frequency of postoperative pulmonary complications and postoperative morbidity. It can even cause chronic pain in the future. Thoracic epidural analgesia (TEA) is the gold standard method in the treatment of pain after thoracotomy. Thoracic paravertebral block (TPVB) is known as the most effective method after TEA. The fact that TPVB has fewer side effects than TEA increases the use of TPVB. There is no consensus on the dose of analgesia in studies. In the literature, volumes between 20 ml and 30 ml are frequently used for TPVB in recent years. This study, it was aimed to compare the efficacy of 20 ml, 25 ml, and 30 ml volumes of TPVB with local anesthetic at the same concentration (0.25% bupivacaine) on postoperative analgesia in patients undergoing thoracotomy.

NCT ID: NCT05600569 Recruiting - Lung Neoplasm Clinical Trials

Registry of the Spanish Society of Thoracic Surgery

ReSECT
Start date: January 1, 2023
Phase:
Study type: Observational [Patient Registry]

ReSECT is a project promoted by the Spanish Society of Thoracic Surgery with the aim not only to become an indefinite, dynamic and inclusive registry, but also to establish a common structural framework for the development of future multicentre projects in the field of thoracic surgery in Spain. The goal of this nationwide prospective observational registry is: - To develop and validate forecasting tools based on powerful computational methods with the goal of assisting in decision-making and improving quality of care. - To evaluate the progressive implementation of certain surgical techniques that are on the rise, new technologies and future health programs. - To be aware of our results as specialty and professionals and to serve as a permanent benchmarking instrument in thoracic surgery. The first part of ReSECT, based on a personal registry design, will contemplate any thoracic surgical procedure performed by thoracic surgeons and residents in thoracic surgery in our country. Additionally, the Spanish thoracic surgery departments that voluntarily accept to collectively participate will contribute to specific surgical processes focused on certain procedures with specific objectives to be progressively implemented. The first and only surgical process implemented since the start of the ReSECT project will focus on patients to undergo anatomical lung resection with special interest in those cases whose reason for intervention was lung cancer. The main questions to answer in case of that first surgical process include: - What is the performance of current predictive models for perioperative and oncological outcomes in our country? - How could we modify previous predictive models to improve their performance? - What is the implementation of current guideline recommendations in our country and across institutions? - What is the potential impact of deviations from current recommendations? - What is my performance compared to the rest of the thoracic surgical departments in my country in terms of perioperative and oncological outcomes? ReSECT does not consider prespecified comparison groups of patients.

NCT ID: NCT05177575 Recruiting - Postoperative Pain Clinical Trials

Incidence of Chronic Pain After Thoracotomy

Start date: December 16, 2021
Phase:
Study type: Observational

Thoracotomy is frequently performed in thoracic surgery. It is widely accepted that thoracotomy causes severe acute pain. Many factors such as postoperative analgesia treatment plan, operation time, number of chest tubes, and duration of chest tube stay can affect acute pain. This acute pain prolongs the discharge time of the patients and increases the frequency of postoperative pulmonary complications and postoperative morbidity. Postoperative acute pain may cause chronic thoracotomy pain in the later period, and may adversely affect the quality of life of the patients. This study aims to analyze the symptoms of chronic pain in the 3rd and 6th months postoperatively in patients who had undergone thoracotomy.

NCT ID: NCT05145153 Recruiting - Postoperative Pain Clinical Trials

Incidence of Chronic Pain After Thoracic Surgery

Start date: September 28, 2021
Phase:
Study type: Observational

Thoracotomy and video-assisted thoracic surgery procedures are frequently performed in thoracic surgery. It is widely accepted that thoracotomy causes severe acute pain. This prolongs the discharge time of the patients, and increases the frequency of postoperative pulmonary complications and postoperative morbidity. Postoperative acute pain may cause chronic thoracotomy pain in the later period, and may adversely affect the quality of life of the patients. Video-assisted thoracic surgery (VATS) has become the standard procedure in minor and major lung surgeries. Postoperative pain is seen in patients undergoing VATS, although it is not as severe as after thoracotomy. As in thoracotomy, this affects the postoperative pulmonary complications and the discharge time of the patients. Likewise, this pain can cause chronic pain. In this study, it was aimed to analyze the symptoms of chronic pain in the 3rd and 6th months postoperatively in patients who had undergone thoracic surgery.

NCT ID: NCT05044858 Recruiting - Postoperative Pain Clinical Trials

Ultrasound-Guided Mid-Point Transverse Process to Pleura Block for Thoracotomy Incisions

Start date: September 24, 2021
Phase: N/A
Study type: Interventional

This study is designed to investigate the analgesic efficacy of pre-emptive ultrasound-guided midpoint transverse process to pleura (MTP) block for posterolateral thoracotomy in cardiothoracic surgeries.

NCT ID: NCT04252378 Recruiting - Pain Management Clinical Trials

Ultrasound-guided Deep and Superficial Serratus Anterior Plane Block

Start date: July 15, 2019
Phase: N/A
Study type: Interventional

This study evaluates the difference of deep and superficial serratus anterior plane block on intraoperative opioid consumption, emergence time and hemodynamic stability in patients undergoing video-assisted thoracic surgery.

NCT ID: NCT04220697 Recruiting - Hyperalgesia Clinical Trials

Central Sensitisation and Postoperative Pain

Start date: January 29, 2020
Phase: N/A
Study type: Interventional

One out of 10 patients undergoing surgery develops persistent post-surgical pain (PPSP). Unfortunately, available therapies for treating this pain have limited success. It is therefore of great importance to find strategies to prevent PPSP. The goal of this project is to find new screening tools that identify patients that are at risk for developing PPSP. Tissue injury and inflammation following surgery increase the excitability of spinal nociceptive neurons ("central sensitisation", CS) with pain hypersensitivity as consequence. It is thought that CS plays an important role in persistent pain. The first objective of this project is to assess in human patients if the propensity to develop CS manifested as secondary hyperalgesia before surgery is predictive for PPSP. In addition, we will test if the frequency content of the resting-state EEG reflecting the initial state of the brain will be related to the propensity for developing CS and to the presence of PPSP at two months after surgery.

NCT ID: NCT04193241 Recruiting - Pleural Effusion Clinical Trials

Suturing With U-Technique Versus Un-Reapproximated Wound Edges During Removal of Closed Thoracostomy Tube Drain

SUTURE
Start date: January 2, 2020
Phase: N/A
Study type: Interventional

The study will be carried out by the principal investigator and his team at the Division of Cardiovascular and Thoracic Surgery of the Department of Surgery, College of Medicine, University of Ibadan and the University College Hospital, Ibadan (UCH), which is the Teaching Hospital of the Medical College.The study sets out to prospectively compare the early and long-term outcomes between the use of purse-string (suturing U-technique) and Un-reapproximated thoracostomy wound edges (Occlusive adhesive-absorbent dressing application) at the time of removal of thoracostomy tube drain in patients who have had chest tube insertion.

NCT ID: NCT03868917 Recruiting - Thoracotomy Clinical Trials

Ultrasound-guided Approach Combined With Pressure Measurement Technique to Thoracic Paravertebral Block

Start date: January 2, 2019
Phase: N/A
Study type: Interventional

Posterolateral thoracotomies are among the most painful procedures of surgery and may cause severe postoperative chest pain and impaired respiratory performance. Paravertebral block (PVB) is an established method of administering postoperative analgesia for thoracic procedures. PVB blocks the somatic and sympathetic nervous systems and is placed by injecting a local anesthetic (LA) into the paravertebral space where the nerve and its branches are located after exiting the intervertebral foramen. But previous study showed 5-10% of failure rate in PVB using ultrasound machine. Pressure measurement during needle advancement could improve reliability of correct needle placement. When the needle tip reaches paravertebral space, there is a sudden lowering of pressures due to respiratory cycle. Therefore, sensitivity and specificity could be improved and correct needle placement become objective and reproducible when PVB using ultrasound is combined with pressure measurement during needle advancement.