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Thoracic Neoplasm clinical trials

View clinical trials related to Thoracic Neoplasm.

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NCT ID: NCT05321615 Not yet recruiting - Lung Cancer Clinical Trials

Feasibility and Safety of a Wireless Palpator

Palpator
Start date: March 1, 2024
Phase: N/A
Study type: Interventional

Evaluation of the ability of the Palpator to detect hidden (occult) lung tumours that cannot be visualized or palpated using the traditional methods of visual inspection, grasper palpation, and VATS ultrasound.

NCT ID: NCT04209868 Recruiting - Anesthesia, Local Clinical Trials

Preoperative Paravertebral Block in Cancer Surgery of the Lung

ParaSOL
Start date: February 1, 2019
Phase: Phase 2/Phase 3
Study type: Interventional

The investigators aim to determine whether ultrasound-guided preemptive paravertebral blockade (PVB) local anaesthetic (pre-PVB LA), administered in addition to the post-operative PVB (post-PVB) local anaesthetic (LA) infusion, reduces acute postoperative pain, opioid requirement, chronic pain, and improves surgical recovery, in thoracoscopic surgery for lung cancer.

NCT ID: NCT03903991 Completed - Anesthesia Clinical Trials

Evaluation of the Reliability of Oesophageal Temperature in THOracic Surgery

ThoTem
Start date: July 18, 2019
Phase:
Study type: Observational

Controlling hypothermia is essential in anesthesia to limit postoperative complications. Temperature monitoring is therefore essential. However, the reliability of esophageal temperature during open chest lung surgery is discussed and not accurately assessed in the literature.

NCT ID: NCT03890640 Completed - Thoracic Neoplasm Clinical Trials

Ultrasound-assisted Thoracic Epidural Catheter Insertion

Start date: July 4, 2019
Phase: N/A
Study type: Interventional

The aim of the present study is to access the success rate of ultrasound-guided thoracic epidural catheter insertion, using fluoroscopy.

NCT ID: NCT03521986 Recruiting - Thoracic Surgery Clinical Trials

Pain and Quality of Life After Mediastinal Tumor Resection by Subxiphoid and Intercostal VATS

Start date: April 4, 2018
Phase: Phase 3
Study type: Interventional

Thoracoscopic assisted mediastinal thymectomy is currently one of the most commonly used surgical methods, but there are some deficiencies.Minimally invasive surgery through the subxiphoid approach can achieve a good surgical field of vision. (1) The surgical field is fully exposed. (2) damage to intercostal nerves can be avoided.(3) Operation time, intraoperative blood loss, postoperative Extubation time is similar to VATS. But there is still lack of evidence. In this study, 50 patients undergoing subxiphoid uniportal VATS and 50 patients undergoing intercostal uniportal VATS were included to evaluate the post-operative pain and quality of life after surgery.

NCT ID: NCT03477162 Terminated - Thoracic Neoplasm Clinical Trials

Metformin Pharmacology in Human Cancers: A Proof of Principle Study

Start date: May 15, 2018
Phase: Early Phase 1
Study type: Interventional

This is a presurgical (proof of principle, window of opportunity) study in patients with surgically resectable thoracic tumors to determine steady-state tissue and plasma concentrations of metformin.

NCT ID: NCT03413449 Active, not recruiting - Lung Cancer Clinical Trials

A Prospective Study Frailty for Esophagectomy and Lung Resection in Thoracic Surgery

Start date: January 8, 2018
Phase:
Study type: Observational

The purpose of this study is to develop an all-encompassing frailty model using laboratory and functional studies. A frailty model will help us determine prior to surgery who will require rehabilitation and skilled nursing needs beyond discharge. This model will also help us determine who will likely be readmitted and why they will be readmitted. Understanding these things can help us prevent some of them from occurring in the future.

NCT ID: NCT03331588 Completed - Clinical trials for Carcinoma, Non-Small-Cell Lung

Comparison of Post-operative Pain and Quality of Life Between Subxiphoid and Intercostal VATS for Lung Cancer

Start date: November 10, 2017
Phase: Phase 3
Study type: Interventional

One-thirds of patients underwent video-assisted thorascopic surgery (VATS) still have severe pain.Uniportal lobectomy or segmentectomies emerged as a promising and exciting approach for minimally invasive thoracic surgery. However, nearly all reported uniportal VATS lobectomies have been performed via the intercostal route, and chest wall trauma has still occurred. Here,the investigators undertook novel uniportal VATS technique involving a subxiphoid route for pulmonary lobectomies or segmentectomies.We would like to evaluate the post-operative pain and quality of life between Subxiphoid and Intercostal VATS for Lung Cancer.

NCT ID: NCT03226925 Completed - Liver Cancer Clinical Trials

Mechanically-assisted Ventilation in the Treatment of Moving Tumours With Photon and Proton Therapies

Start date: June 30, 2017
Phase: N/A
Study type: Interventional

Mechanical ventilation can be used to impose a completely regular pattern of breathing frequency and inflation volume on the patient for as long as required. This would considerably improve the reproducibility of the internal motion parameters, and thus facilitate the implementation of respiratory-synchronized techniques such as gating, tracking and four-digital optimization.

NCT ID: NCT03168048 Not yet recruiting - Breast Cancer Clinical Trials

Oncologic Therapy Support Via Means of a Dedicated Mobile App

OPTIMISE-1
Start date: July 2017
Phase: N/A
Study type: Interventional

The present single-center prospective exploratory study, conducted at Heidelberg University Hospital, assesses the feasibility of introducing a concept for additional patient care based on a mobile application for patients undergoing radiotherapy. Patients presenting themselves for the irradiation of thoracic or pelvic tumors will be surveyed regarding general performance, treatment-related Quality of Life (QoL) and symptoms and their need to personally consult a physician on a treatment-daily basis by means of a mobile application. The primary endpoint of feasibility will be reached when 80% of the patients have successfully answered 80% of their respective questions scheduled for each treatment day. Furthermore, treatment-related patient satisfaction and diagnosis-related QoL is assessed by PSQ-18 and EORTC questionnaires at the end of radiotherapy and at the first follow-up.