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Survivorship clinical trials

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NCT ID: NCT06411704 Recruiting - Frailty Clinical Trials

Remote Exercise Video Adaptations to Maximize Physical Activity in Childhood Cancer

Start date: May 2024
Phase:
Study type: Observational

The goal of this observational study is to leverage childhood cancer survivor input to adapt video content of a digital video disc-(DVD) delivered evidence-based PA intervention, originally designed for community-dwelling older adults. Primary Objective: - To leverage childhood cancer survivor input to adapt video content for an evidence-based remote exercise intervention.

NCT ID: NCT06353178 Recruiting - Cancer Clinical Trials

Building Empowerment and Coping Outcomes for caNcer Patients, Survivors and Their Caregivers

BEACON
Start date: April 8, 2024
Phase: N/A
Study type: Interventional

Cancer has a psychological, emotional and social impact beyond a patient's physical health. This study examines three new online peer mental-wellness support program for cancer patients, survivors or their caregivers. Each program teaches evidence-based skills, in the context of that groups lived experience, to manage the emotional impact of cancer. This study examines the impact of that program.

NCT ID: NCT06320223 Recruiting - Prostate Cancer Clinical Trials

PROMISE PET Registry on PSMA-PET and Outcome in Prostate Cancer

PROMISE-PET
Start date: March 5, 2024
Phase:
Study type: Observational [Patient Registry]

Background: PROMISE criteria have been defined for standardized reporting of Prostate-Specific Membrane Antigen (PSMA) PET whole-body stage of prostate cancer. PSMA PET disease extent by PROMISE has been associated with oncologic outcome. Need: Improved prognostication across various stages of prostate cancer is needed for management guidance and study design. Aim: 1. To assess the prognostic value of PSMA PET 2. To compare the prognostic value of PSMA PET with clinical prognostic scores in patients with prostate cancer at various disease stages Inclusion: - Adult patients with - biopsy/histo proven prostate cancer who - underwent PSMA PET (any type) - for staging or re-staging at any stage and who - have at least 3-year overall survival follow-up data available will be included consecutively. Exclusion: - Patients with neuroendocrine prostate cancer - Patients with metastasized or disseminated malignancy other than prostate cancer

NCT ID: NCT06306170 Recruiting - Gynecologic Cancer Clinical Trials

Advanced Radiotherapy (ART) in Gynecological Cancer Patients (GYN-ART)

GYN-ART
Start date: February 15, 2024
Phase:
Study type: Observational

This is an observational mono-institutional study. Patients with gynecologic tumors treated with advanced radiotherapy- Image Guided Radiotherapy (IGRT), Intensity Modulated Radiotherapy (IMRT), Stereotactic Body Radiotherapy (SBRT)- will be included and toxicity and outcomes analyzed.

NCT ID: NCT06284395 Recruiting - Survivorship Clinical Trials

Two Schemes Response in Multiple Myeloma

Start date: November 20, 2023
Phase:
Study type: Observational

Retrospective study based on medical records of patients with multiple myeloma, eligible for stem cell transplantation, who received, first-line, the VTD or TD combination.

NCT ID: NCT06172907 Recruiting - Cancer Clinical Trials

A Dyadic Intervention for Young Adult Patients With Cancer and Their Partner Caregivers

YAD
Start date: April 19, 2024
Phase: N/A
Study type: Interventional

The purpose of this pilot study is to examine the feasibility and acceptability of a brief psychotherapy intervention to improve psychosocial coping and maintain couple relationships among young adults (aged 25-39) with cancer and their caregiving partners.

NCT ID: NCT05968144 Recruiting - Aging Clinical Trials

Towards Understanding Between ADT Treatment, Circadian Rhythm, and Physiological Responsiveness

ADRIAN
Start date: January 29, 2024
Phase: Phase 1/Phase 2
Study type: Interventional

Frailty is one of the main reasons older adults lose independence. Frailty describes a reduced ability to withstand stress on the physiological scale, or a reduced physiological reserve. The theory is that entrainment of circadian rhythm via time-restricted eating will improve the body's ability to predict energy supply and demand, and therefore enable the body to allocate more resources to anabolic processes and promote resilience to cancer treatment, thereby preventing the progression of frailty. A total of 30 individuals over 55 years old undergoing ADT therapy for prostate cancer will be recruited. Participants will be randomized 1:1 to a 12-week TRE intervention or a time-unrestricted nutrition control intervention. At baseline and post-intervention, Fried's Frailty Index will be used to assess frailty, and a novel set of five physiological responsiveness measures will be used to assess physiological responsiveness-1) lying-to-standing blood pressure, 2) heart rate variability, 3) oral glucose tolerance test, 4) 24-hour circadian cortisol rhythm, and 5) usual vs. fast gait speed. These data will allow assessment of 1) the feasibility of TRE among patients with prostate cancer during ADT treatment with the ultimate goal of optimizing an intervention to prevent the progression of frailty, and 2) the effects of TRE vs. control on frailty and physiological responsiveness.

NCT ID: NCT05946993 Recruiting - Prostate Cancer Clinical Trials

Linking In With Advice and Supports for Men Impacted by Metastatic Cancer

LIAM Mc
Start date: May 8, 2023
Phase: N/A
Study type: Interventional

To evaluate the feasibility of introducing a men's cancer survivorship programme into routine follow up care in patients with advanced genitourinary malignancies.

NCT ID: NCT05905250 Recruiting - Cancer Clinical Trials

mHealth for Young Adult Cancer Survivors

mHealthAYA
Start date: March 15, 2024
Phase: N/A
Study type: Interventional

We aim to refine and pilot test an 8-week phone- and app-based intervention to promote hope, and thereby mitigate life disruption caused by cancer diagnosis and treatment, among young adults (YAs); our proposal involves (Aim 1) formative research among YA survivors and healthcare providers; and (Aim 2) an randomized controlled trial (RCT) of the intervention vs. attention control among 150 YA cancer survivors. The proposed research is innovative in its use of: 1) a novel intervention target - hope - as a mechanism for addressing goal-disruption and quality of life (QOL) among YA survivors; and 2) novel mHealth components and population-based recruitment strategy (via social media) that are particularly relevant to YA survivors and those with potentially limited access to healthcare. This proposal has potential high impact due to the number of YA cancer survivors for whom the intervention may be relevant, the intervention's potential utility in enhancing hope and QOL among YAs, and its reach/scalability.

NCT ID: NCT05876338 Recruiting - Colorectal Cancer Clinical Trials

Colorectal Cancer Survivor Symptom Management

CRCaSSM
Start date: July 11, 2023
Phase: N/A
Study type: Interventional

Objective: The aim of this study was to examine the effects of nursing interventions based on the symptom management model on symptom management, fear of recurrence, and quality of life in colorectal cancer survivors. Method: The research was planned as a randomized controlled trial. The research is planned to be carried out at Akdeniz University Hospital. It is planned to be done with 52 patients, 26 experimental and 26 control groups. The intervention group will receive face-to-face training and telephone counseling based on the symptom management model. After the training, it is planned to provide telephone counseling for a total of 6 times, once every 2 weeks for 3 months. Participant Information Form, Memorial Symptom Assessment Scale, Fear of Cancer Recurrence Inventory and European Organization for the Research and Treatment of Cancer Quality of Life Questionnaire Scale Scale will be used to collect data.