Clinical Trials Logo

Surgery clinical trials

View clinical trials related to Surgery.

Filter by:

NCT ID: NCT03388814 Withdrawn - Breast Cancer Clinical Trials

Speeding Recovery From Pain and Opioid Use

Start date: November 2018
Phase: Early Phase 1
Study type: Interventional

Surgical treatment of breast cancer is associated with significant disability, and pain is often reported as a primary cause for declines in the ability to perform activities of daily living. However, breast reconstruction at the same time as mastectomy has been linked to higher postoperative pain, which can be a risk factor for persistent pain. The goal of this study is to determine the speed of recovery from pain and opioid use in the first 2 months after breast surgery and reconstruction.

NCT ID: NCT03369782 Withdrawn - Surgery Clinical Trials

Effect of NMBA on Surgical Conditions in THR

Start date: December 15, 2017
Phase: Phase 4
Study type: Interventional

During Total hip replacement arthroplasty (THA), the hip joint first must be luxated in order to have access to the joints. A lot of force and torque must be carried out on the joint to perform this manipulation. This is both difficult for the surgeon and may cause additional tissue damage and postoperative pain. After placement of the prosthesis and reduction of the joint, the tension of the hip joint must be evaluated by the surgeon to ascertain the adequacy of the prosthesis. During luxation, minimal muscle tension would be ideal, while after reduction of the joint, normal muscle tension is desired to permit assessment of the mechanics of the hip joint. The aim of the study is to investigate whether deep neuromuscular block, combined with a reversal before mechanics assessment improves surgical conditions, surgical time, and postoperative patient comfort.

NCT ID: NCT03228043 Withdrawn - Colorectal Cancer Clinical Trials

Apatinib for Resectable Colorectal Cancer

Start date: March 1, 2020
Phase: N/A
Study type: Interventional

Objective: To compare the outcome of patients with colorectal cancer who treated with adjuvant therapy or Apatinib with adjuvant therapy postoperatively. Language: English.

NCT ID: NCT03187171 Withdrawn - Surgery Clinical Trials

ACDF Comparison Trial

Start date: December 1, 2018
Phase: N/A
Study type: Interventional

This research protocol seeks to compare radiological and clinical outcomes of cervical spine disease patients following standard-of-care anterior cervical discectomy and fusion (ACDF) using allograft fusion versus Cohere porous polyetheretherketone (PEEK) fusion device. This clinical study presents little to no additional risk to study subjects beyond those associated with standard-of-care ACDF surgery. Adults age 18 and over who are undergoing an ACDF procedure will be enrolled in the study. The study consists of a completing a series of questionnaires and obtaining radiographs. The primary endpoint of the study will be the rate of successful spinal fusion for each group. For evaluation of the primary endpoint and additional assessments, descriptive statistics including mean, standard deviation, minimum, median, and maximum for continuous variables and frequency distribution for categorical variables will be provided, as well as tabular listings. All complications will be itemized including incidence, duration, and relationship to the device used and/or procedures performed.

NCT ID: NCT02997098 Withdrawn - Surgery Clinical Trials

Longitudinal Outcomes in Hepatic Resection

Start date: May 4, 2017
Phase:
Study type: Observational [Patient Registry]

This observational registry of patients undergoing liver surgery collects patients both retrospectively and prospectively. Patients undergoing liver resection for any non-transplant indication will be evaluated for clinical outcomes (such as surgical complications, survival, and disease progression) based on clinical and patient factors (like indication, age, and other treatments for the disease).

NCT ID: NCT02953691 Withdrawn - Pain Clinical Trials

Exploring the Impact of Perioperative Galacto-Oligosaccharides (GOS) on Stress, Anxiety and Cognition

Start date: June 9, 2017
Phase: Phase 2
Study type: Interventional

The overall objective of this proposal is to explore the association between the administration of the prebiotics GOS (trade name: Bimuno Travelaid; generic name:B galacto-oligosaccharides) with pain, anxiety, and cognitive function in the perioperative period. The investigators' central hypothesis is subjects who consume GOS in the perioperative period will demonstrate lower levels of salivary cortisol before, during, and after their operative procedures. In addition, the investigators expect subjects who consume GOS to have lower perceived levels of anxiety during the perioperative period. Finally, the investigators hypothesize that subjects who consume perioperative GOS will perform better on tests of cognition in the postoperative period. Such a finding would be beneficial in that administration of GOS in the perioperative period offers a safe and inexpensive adjunct to current medical management of perioperative anxiety.

NCT ID: NCT02881541 Withdrawn - Surgery Clinical Trials

Study of the Benefit of a Nurse (IDE) Pre and Post-operative Framework in Proctology Outpatient Surgery

IDEPROCTO
Start date: May 4, 2015
Phase: N/A
Study type: Interventional

Evaluate the complement of patient care course in the development of proctology outpatient surgery (CAP) by providing: - An additional preoperative nurse consultation day hospital - And a phone call from a nurse at D + 1 of the operation This corresponds to a reinforced support.

NCT ID: NCT02860897 Withdrawn - Surgery Clinical Trials

Patient Adherence to Premarin Versus Vagifem Therapy After Female Pelvic Reconstructive Surgery

Start date: July 2016
Phase: Phase 4
Study type: Interventional

PURPOSE: To evaluate patient adherence to cream versus tablet based local estrogen therapy by randomizing treatment modalities to determine differences in adherence to either form. HYPOTHESIS: There is no difference in adherence to cream versus tablet based local estrogen therapy when prescribed as a 6 week course of postoperative therapy after female pelvic reconstructive surgery.

NCT ID: NCT02819544 Withdrawn - Pain Clinical Trials

Evaluation of the Interest of the Instillation of Saline Intraperitoneally (INSI ) Versus Instillation of Naropin the Surgical Site Versus Lung Recruitment Maneuvers ( PVM ) in the Management of Pain After Laparoscopic Cholecystectomy in Ambulatory Care

VSD
Start date: September 2016
Phase: Phase 3
Study type: Interventional

Known to reduce analgesics and length of hospitalization in conventional surgery, laparoscopy is characterized by frequent post-operative pain and can decrease the patient's quality of immediate postoperative life and sometimes the results of decision ambulatory care. In order to reduce these postoperative pain, various methods have been evaluated in numerous studies to determine their analgesic role. As part of abdominal surgery, local anesthetics (Naropin (Ropivacaine)) are generally administered in the end of surgery to reduce postoperative pain and promote recovery of the patient. In addition, it is also possible to instill the anesthetic directly into the abdominal cavity reducing pain transmitted by nociceptor viscera. In recent years, new methods have been proposed such as lung recruitment maneuvers and the instillation of saline solution to reduce postoperative pain. However, no recommendation is on the use of intraperitoneal saline under the management of postoperative pain after laparoscopic cholecystectomy in ambulatory care.

NCT ID: NCT02807571 Withdrawn - Surgery Clinical Trials

Office Based Hand Surgery Using WALANT (Wide Awake Local Anesthesia No Tourniquet): Outcomes and Cost Savings Analysis

WALANT
Start date: February 10, 2017
Phase:
Study type: Observational

This study is aimed at determining if office based surgery is an effective way of cutting health care cost while maintaining patient safety and satisfaction.