Prognostic Factors and Mortality in Older Stroke Patients With Mechanical Thrombectomy

Stroke, Ischemic Clinical Trial

Official title:

Prognostic Factors in Disease Progression and Mortality Risk in the Older Stroke Patients With Mechanical Thrombectomy

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04672148
• Other study ID #: 109125-E
• Status: Completed
• Start date: December 1, 2020
• Est. completion date: December 11, 2020

Study information

• Verified date: December 2020
• Source: Far Eastern Memorial Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The study focus on the elderly patient (older than 80 years of age) who had acute ischemic stroke and received mechanical thrombectomy. The investigators analyze different factors in the stage of before, between, after procedure and trying to figure out if there is any difference between the 30-day-mortality group versus non-30-day-mortality group.

Description:

With the constant improvements in health care, standard of living and the decrease birth rate, the percentage of the elderly population ( above 80 years old) is expected to double in Taiwan by the year 2044, according to data from the National Development Council. Consequently with the increase in the proportion of senior citizens, there will be an surge number of patient suffering from cardiovascular and cerebrovascular diseases, most importantly acute ischemic stroke. In recent years, mechanical thrombectomy has become the gold standard in the treatment for acute stroke patients, however, many studies have excluded the patients above the age of 80 years old as the benefits of the procedure have been very controversial and there is no clear evidence proving favorable a outcome. There are a few studies which state that though elderly patients had higher risk of complications when receiving mechanical thrombectomy as compared to younger patients, the prognosis was still superior to those didn't receive any intervention. Previous studies put more emphasis on the overall prognosis, morbidity and mortality rate, they didn't focused on the cause of mortality.

The study focuses on analyzing of the cause of mortality and whether there is a significant difference between 30-day-mortality group versus non-30-day-mortality group.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 48
• Est. completion date: December 11, 2020
• Est. primary completion date: December 5, 2020
• Accepts healthy volunteers: No
• Gender: All
• Age group: 80 Years to 110 Years

Eligibility

Inclusion criteria:

1. elderly (older than 80 years old)

2. acute ischemic stroke in anterior circulation

3. NIHSS more than 8

Exclusion Criteria:

1. posterior infarction

2. ASPECT score less than 3

Related Conditions & MeSH terms

• Ischemic Stroke
• Stroke
• Stroke, Ischemic

Locations

Country	Name	City	State
Taiwan	Far Eastern Memorial Hospital	New Taipei city

Sponsors (1)

Lead Sponsor	Collaborator
Far Eastern Memorial Hospital

Country where clinical trial is conducted

Taiwan, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	30 days mortality	Patient who died in the 30 days after receiving mechanical thrombectomy	30 days
Secondary	The cause of mortality	Analyse the main cause of mortality	30 days