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Stroke, Ischemic clinical trials

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NCT ID: NCT05046106 Not yet recruiting - Stroke Clinical Trials

MLC1501 Study Assessing Efficacy in STROke Recovery

MAEStro
Start date: January 2025
Phase: Phase 2/Phase 3
Study type: Interventional

This is a multi-center, randomized, double-blind, placebo-controlled, dose-response study of MLC1501 in patients with stroke. Eligible participants will be randomized in a 1:1:1 ratio to orally receive MLC1501 low-dose twice a day, MLC1501 high-dose twice a day, or matching placebo for 24 weeks.

NCT ID: NCT05035953 Not yet recruiting - Stroke, Ischemic Clinical Trials

Thrombolysis Combined With Edaravone Dexborneol on Hemorrhagic Transformation for Acute Ischemic Stroke

Start date: September 13, 2021
Phase: Phase 2
Study type: Interventional

To explore the safety and efficacy of edaravone dexborneol for the treatment of acute ischemic stroke patients who received thrombolysis.

NCT ID: NCT04920448 Not yet recruiting - Stroke, Ischemic Clinical Trials

N-ACETYLCYSTEINE FOR THROMBOLYSIS IN ACUTE STROKE

NAC-S
Start date: June 7, 2021
Phase: Phase 2
Study type: Interventional

The primary objective of the study is to assess the safety of N-Acetylcysteine as a thrombolytic agent in acute ischemic stroke, especially regarding the risk of hemorrhagic transformation.

NCT ID: NCT04882657 Not yet recruiting - Stroke, Acute Clinical Trials

Collateral Circulation in Acute Ischemic Stroke With Large Vessel Occlusion

COLISEUM
Start date: June 1, 2021
Phase:
Study type: Observational

Prospective multicenter study of consecutive patients with acute ischemic stroke and large intracranial vessel occlusion in which a thorough and systematic evaluation of all variables that may be related to the degree of collateral circulation is performed.

NCT ID: NCT04804085 Not yet recruiting - Anesthesia Clinical Trials

Anaesthesia for Mechanical Thrombectomy

Start date: June 1, 2021
Phase:
Study type: Observational

Title: Conduct of anaesthesia during acute ischaemic stroke: a retrospective case series of patients undergoing mechanical thrombectomy. Design: This study will be a retrospective consecutive observational case series

NCT ID: NCT04726943 Not yet recruiting - Atrial Fibrillation Clinical Trials

RF Applications for Residual LAA Leaks

REACT
Start date: February 1, 2021
Phase: N/A
Study type: Interventional

Although the clinical impact of residual left atrial appendage (LAA) leaks still requires confirmation, its patency resulting from incomplete LAA closure may promote blood stagnation and thrombus formation, and increase the risk of thromboembolic events. The main purpose of this trial is to evaluate the safety and efficacy of percutaneous leak closure with radiofrequency energy applications.

NCT ID: NCT04697979 Not yet recruiting - Stroke, Ischemic Clinical Trials

Post-Stroke Medication Relay

REMEDIPA
Start date: February 2021
Phase:
Study type: Observational

Prior to discharge from hospital and return home, patients managed for ischemic stroke will receive a pharmaceutical interview to discuss their discharge prescription (indication, method of administration, precautions, and possible side effects). Improvements in the use of medications in the community and in hospital follow-up. Telephone interviews or teleconsultations will make it possible to assess the patient's knowledge of his or her treatment and to re-explain it if necessary to improve patient compliance with treatment.

NCT ID: NCT03726814 Not yet recruiting - Stroke, Ischemic Clinical Trials

A Clinical Study of iEPC Intervent Subjects With Cerebral Hemorrhagic Stroke

Start date: December 2018
Phase: Early Phase 1
Study type: Interventional

This is a single centre、single arm、open-label,to investigate the safety and efficacy of EPC transplantation in the brain

NCT ID: NCT03725865 Not yet recruiting - Stroke, Ischemic Clinical Trials

A Clinical Study of iNSC Intervent Cerebral Hemorrhagic Stroke

Start date: March 2019
Phase: Early Phase 1
Study type: Interventional

This is a single centre、single arm、open-label,to investigate the safety and efficacy of induction of neural stem cells transplantation in the brain

NCT ID: NCT03725137 Not yet recruiting - Cognitive Decline Clinical Trials

Post-stroke Immunological Changes in Young Stroke Patients

Start date: January 2020
Phase:
Study type: Observational

In the present study, the investigators aim to elucidate the role of T-cells on cognitive decline in younger stroke patients, using repeated cognitive testing, brain imaging, and immunological analyses in the first 6 month after stroke. The examiners will investigate (i) the extent and duration of stroke-induced changes in T cell function within the peripheral blood of patients; and (ii) post-stroke cognitive functions.