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Stroke, Ischemic clinical trials

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NCT ID: NCT03275155 Active, not recruiting - Atrial Fibrillation Clinical Trials

Pathophysiology and Risk of Atrial Fibrillation Detected After Ischemic Stroke

PARADISE
Start date: April 18, 2017
Phase:
Study type: Observational

This prospective non-interventional cohort study investigates the pathophysiology of Atrial Fibrillation Detected After Stroke or transient ischemic attack (AFDAS) by comparing the autonomic function and inflammation between patients with AFDAS, patients with atrial fibrillation (AF) diagnosed before the ischemic event or known AF (KAF), and patients with normal sinus rhythm (NSR) after 14 day of cardiac monitoring following the event onset.

NCT ID: NCT03211130 Completed - Stroke, Ischemic Clinical Trials

Using SystemCHANGE™ to Enhance Medication Adherence in Older Adult Stroke Survivors

Start date: November 28, 2017
Phase: Early Phase 1
Study type: Interventional

This study evaluated the feasibility and acceptability of using a SystemCHANGE intervention in older adult stroke survivors to improve medication adherence. Half the participants will receive the SystemCHANGE intervention, while the other half will receive the attention-control education intervention.

NCT ID: NCT03199404 Terminated - Stroke, Ischemic Clinical Trials

Trevo Aspiration Proximal Flow Control Registry

TRAP
Start date: June 6, 2017
Phase:
Study type: Observational [Patient Registry]

This purpose of this retrospective, single-arm, non-randomized, multi-center study is to collect real-world data on the effectiveness of using the TRAP technique in acute ischemic stroke patients undergoing mechanical thrombectomy.

NCT ID: NCT03195907 Completed - Rehabilitation Clinical Trials

Pulmonary Physiotherapy for Ischemic Stroke

Start date: February 1, 2015
Phase: N/A
Study type: Observational

This study evaluates the predictors of intensive care unit admission and mortality among stroke patients and the effects of pulmonary physiotherapy on these stroke patients. One-hundred patients participated in the pulmonary rehabilitation program and 81 patients served as a control group.

NCT ID: NCT03177161 Completed - Stroke Clinical Trials

Assessment of Patient Reported Health Status Questions Via Four Different Methods of Administration, in Stroke Survivors.

Start date: August 12, 2017
Phase: N/A
Study type: Interventional

A Patient Reported Outcome Measure (PROM) is a questionnaire that asks patients for their views on their own health or the impact of healthcare they have received on their health and quality of life (RCN, 2011). The benefit of PROMS is that they gather information from the patient's perspective, which offers great potential to improve the quality and outcomes of health services (Department of Health 2011). There is a PROM (the PROMIS-10 Global Health) and a number of extra questions that are recommended for use in people who have had a stroke by the International Consortium for Health Outcomes Measurement, but the best way of delivering these questions for stroke survivors is unknown. At present, the NHS in England, Scotland and Wales are required to offer every stroke survivors a 6 month post stroke follow-up appointment. Currently, the information collected at the 6 month review is not from the patient's perspective and the best method of collecting this information has not been established. The Sentinel Stroke National Audit Programme (SSNAP) which is led by the Royal College of Physicians in London promote the 6 month follow-up assessment. SSNAP recognise that currently 4 different methods of 6 month follow-up appointment occur. The current methods in use are face-to-face assessment, telephone interview, online questionnaire or postal questionnaire. The aim of this research is to understand if there is a difference between these 4 methods of delivering these questions in people who have had a stroke. As part of the 6 month review this research study will assess the response rate for 15 Patient Reported Health Status questions across the 4 recognised methods of delivery; - Face-to-Face - Telephone - Online - Post To conduct this research study a sample of 808 stroke survivors will be asked to take part in the research. From these 808 people, 202 participants will be randomly assigned to each method of administration (Face-to-Face Interview, Telephone Interview, Postal Questionnaire and Online Questionnaire). The questionnaires received by the research team will not record any personally identifiable information. The data will then be utilised by the researchers for statistical analysis in order to identify, which method of the 4 methods of administration, under investigation, is the most acceptable for stroke survivors. The conclusions of this research will inform the roll-out of the most appropriate method of delivering the 6 month stroke follow-up review for stroke survivors.

NCT ID: NCT03160131 Recruiting - Clinical trials for Traumatic Brain Injury

Rehabilitation of Visual Function After Brain Injury

IBOS-NVT
Start date: August 1, 2017
Phase: N/A
Study type: Interventional

In Denmark, about 120,000 people suffer from brain damage, of whom approx. 75,000 with brain damage after stroke. Serious and often lasting vision impairments affect 20% to 35% of people after stroke. Vision is the most important sense in humans, and even smaller permanent injuries can drastically reduce quality of life. Vision impairments after brain damage inhibits rehabilitation and enhances other invalidating effects. Reduced vision results in impaired balance, increased risk of serious falls, increased support needs, reduced quality of life, and impaired ability to perform activities of daily living. Restoration of visual field impairments occur only to a small extent during the first month after brain damage, and therefore the time window for spontaneous improvements is very limited. Hence, brain-impaired persons with visual impairment will most likely experience chronically impaired vision already 4 weeks after brain injury and the need for visual compensatory rehabilitation is substantial. Neuro Vision Technology (NVT) is an supervised training course where people with visual impairments are trained in compensatory techniques using special equipment. Through the NVT process, the individual's vision problems are carefully investigated and personal data is used to organize individual training sessions that practice the individual in coping with situations that cause problems in everyday life. The purpose of this study is to investigate whether rehabilitation with NVT can cause significant and lasting improvement in functional capacity in persons with chronic visual impairments after brain injury. Improving eyesight is expected to increase both physical and mental functioning, thus improving the quality of life. Participants included in the project will be investigated in terms of both visual and mental functions, including quality of life, cognition and depression. Such an investigation has not been performed previously and can have a significant impact on vision rehabilitation both nationally and internationally.

NCT ID: NCT03098732 Suspended - Stroke, Acute Clinical Trials

Magnetically Enhanced Diffusion for Acute Ischaemic Stroke (MEDIS) Trial

MEDIS
Start date: March 22, 2017
Phase: N/A
Study type: Interventional

The objective of the MEDIS study is to determine if subjects experiencing an Acute Ischaemic Stroke due to large vessel occlusion, treated with IV tPA combined with the MED procedure have a greater likelihood of recanalisation 30-90 minutes after the completion of tPA infusion than subjects treated with IV tPA (plus sham device). Safety of the MED System Procedure will be evaluated by the incidence of symptomatic PH-2 haemorrhagic transformation within 24 hours following the procedure. Lastly, a health economics study will be conducted to estimate health care costs for each treatment.

NCT ID: NCT03067818 Completed - Stroke Clinical Trials

Mechanisms of Arm Recovery in Stroke Patients With Hand Paralysis

Start date: June 20, 2017
Phase: N/A
Study type: Interventional

This study examines the effect of non-invasive brain stimulation targeting different brain areas on movement of the affected arm post-stroke. Participants will receive stimulation to each of 3 different brain areas combined with a session of arm exercise.

NCT ID: NCT03038685 Completed - Stroke, Ischemic Clinical Trials

A Personalized, Digital Coaching Program After Stroke

STROKECOACH
Start date: May 1, 2017
Phase: N/A
Study type: Interventional

The Belgian Stroke Council initiated a project to improve risk factor control and medication adherence in ischemic stroke patients by developing an individualized in-hospital initiated and post- discharge, digital coaching program addition to standard practice (strokecoach.be).

NCT ID: NCT02988128 Recruiting - Stroke, Ischemic Clinical Trials

Neurovascular Product Surveillance Registry

INSPIRE
Start date: December 2016
Phase:
Study type: Observational [Patient Registry]

Post market surveillance registry