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Respiratory Distress clinical trials

View clinical trials related to Respiratory Distress.

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NCT ID: NCT06146439 Completed - Clinical trials for Respiratory Distress

The Factors Causing Treatment Failure in Children Receiving Oxygen Therapy With High-flow Nasal Cannula

Start date: October 1, 2018
Phase:
Study type: Observational [Patient Registry]

The goal of this observational study is to identify the variables that predict treatment failure in order to identify the patients in which HFNC treatment may fail and not delay the transition to advanced respiratory support treatments in these patients. The main questions it aims to answer are: - What factors contribute to the failure of HFNC treatment in these children? - What is the frequency of HFNC treatment failure in children with moderate and severe respiratory distress? Researchers will compare the group whose HFNC treatment was successful with the group whose HFNC treatment failed to identify factors that cause treatment failure.

NCT ID: NCT05328206 Recruiting - Clinical trials for Respiratory Distress

Air Leak Test In Pediatric Intensive Care Unit

ALTIPICU
Start date: October 5, 2022
Phase:
Study type: Observational

Respiratory distress by upper airway obstruction (UAO) is the primary etiology of extubation failure in children hospitalized in pediatric intensive care unit (PICU). This complication may require various invasive therapeutic which increase morbi-mortality and length of hospital stay. Cuff leak test (CLT) measured prior extubation to predict post-extubation UAO has been widely used in adult. The test compared expired tidal volume with cuff inflated and cuff deflated in order to predict UAO. Despite its frequent use in PICU, his predictive value to predict UAO in children is still poorly documented. Therefore, we conducted the first multicentric, prospective study to evaluate the CLT as a predictor of post-extubation UAO in critically ill children. The Primary objective is to assess the effectiveness of CLT in predicting severe respiratory distress by UAO within 48 hours of extubation in a critically ill children.

NCT ID: NCT05220644 Not yet recruiting - Pain Clinical Trials

Management of Pain Respiratory Distress at the End of Life in Newborn Palliative Care in the Delivery Room

PALLI-ACC
Start date: February 2022
Phase:
Study type: Observational

The newborn feels pain and the newborn at the end of life, in the delivery room, is potentially exposed to pain and respiratory distress. Protocols for the management of end-of-life symptoms in the delivery room are used in current practice with very few validation studies. The protocol used in delivery rooms in Alsace uses fentanyl and midazolam intranasally. It has been used for 3 years and seems to provide satisfactory relief to newborn babies. In doing so, it seems to reassure parents about the quality of support and it seems to meet the expectations of professionals in these anxiety-provoking contexts. Scientific validation of these practices would allow wider dissemination to other maternity teams.

NCT ID: NCT04758078 Recruiting - Clinical trials for Respiratory Distress

Inhaled Budesonide in Transient Tachypnea of the Newborn

Start date: February 15, 2021
Phase: N/A
Study type: Interventional

Background: Transient tachypnea of the newborn (TTN) caused by lung edema resulting from delayed absorption of fetal alveolar lung fluid and is a common cause of admission of late preterm and full-term infants to neonatal intensive care units. Infant born by C-section and those with perinatal asphyxia, umbilical cord prolapse or certain maternal condition (asthma, diabetes, or analgesia) are more prone to develop TTN. Conventional treatment involves appropriate oxygen administration and continuous positive airway pressure in some cases. Hastening the clearance of lung liquid should shorten the duration of the symptoms and reduce complications. Objectives: This study aims to determine the effectiveness of inhaled budesonide in the treatment of this disorder through determining whether it reduces the duration of oxygen therapy and respiratory symptoms and shortens hospital stay in term infants with transient tachypnea of the newborn

NCT ID: NCT02208323 Completed - Hypoxia Clinical Trials

Advancement of Modified Bubble CPAP

Start date: July 2015
Phase: Phase 2
Study type: Interventional

This study proposes that modifying the current form of bCPAP by adjusting the nasal prongs to fit older children, will create a safe form of respiratory support that may help to decrease respiratory distress and thus mortality from pneumonia.

NCT ID: NCT02000674 Completed - Shock Clinical Trials

Succinylcholine vs Rocuronium for Prehospital Emergency Intubation

CURASMUR
Start date: December 2013
Phase: Phase 3
Study type: Interventional

All adult patients with spontaneous cardiac activity and requiring tracheal intubation in the pre hospital emergency context will be included in order to compare the use of succinylcholine vs Rocuronium for prehospital emergency intubation.

NCT ID: NCT01939067 Withdrawn - Lung Injury Clinical Trials

Infant Pulmonary Mechanics: High Flow Nasal Cannula Versus Nasal CPAP

Start date: March 2014
Phase: Phase 1
Study type: Interventional

This study is designed to evaluate the effect of heated humidified high flow nasal cannula (HHHFNC) as compared to noninvasive nasal continuous positive airway pressure (NCPAP) on lung function as a measure of lung injury in preterm infants born at 28 to 37 weeks gestation requiring continuing respiratory support.

NCT ID: NCT01845506 Not yet recruiting - Obesity Clinical Trials

The Application of a Wireless Sensor Technology for Vital Statistics in CHILDREN AND ADULTS

Start date: December 2021
Phase: N/A
Study type: Interventional

The primary outcome for this project will be the development of a small, non-invasive wireless sensor that is linked to a conventional computer that can be used in health care for monitoring of acute and chronic health problems. The advantages of developing this technology are threefold. First, monitoring can be conducted for a fraction of the cost of a bedside nurse. Second, monitoring can be done in real time and stored so that we can diagnose and manage critical events in a more timely manner. Lastly, many patients can be monitored simultaneously. The wireless sensors will be fitted to healthy volunteers of various ages. The data gathered from the sensor with respect to their vital signs will be compared to that of conventional tools such as nursing assessments and pulse oximetry.

NCT ID: NCT01310153 Completed - Clinical trials for Transient Tachypnea of the Newborn

Effect of Supine or Prone Position After Caesarean Birth

Start date: September 2006
Phase: N/A
Study type: Interventional

Respiratory Distress is a frequent clinical diagnosis of babies delivered by elective Caesarean birth. There has been no study comparing the efficacy of immediately positioning a newly born infant prone vs. supine for the first 30 60 seconds of life after delivery by Caesarean birth.

NCT ID: NCT00889772 Completed - Acute Lung Injury Clinical Trials

Lung Injury Prediction Study

USCTG-LIPS1
Start date: March 2009
Phase: N/A
Study type: Observational

The purpose of the study is to externally validate the acute lung injury/acute respiratory distress syndrome (ALI/ARDS) prediction model (Lung Injury Prediction Score - LIPS) in a multicenter sample of patients at risk presented to the acute care hospitals: United States Critical Illness and Injury Trials Group (USCIITG).