Clinical Trials Logo

Respiratory Distress clinical trials

View clinical trials related to Respiratory Distress.

Filter by:
  • Completed  
  • Page 1

NCT ID: NCT06146439 Completed - Clinical trials for Respiratory Distress

The Factors Causing Treatment Failure in Children Receiving Oxygen Therapy With High-flow Nasal Cannula

Start date: October 1, 2018
Phase:
Study type: Observational [Patient Registry]

The goal of this observational study is to identify the variables that predict treatment failure in order to identify the patients in which HFNC treatment may fail and not delay the transition to advanced respiratory support treatments in these patients. The main questions it aims to answer are: - What factors contribute to the failure of HFNC treatment in these children? - What is the frequency of HFNC treatment failure in children with moderate and severe respiratory distress? Researchers will compare the group whose HFNC treatment was successful with the group whose HFNC treatment failed to identify factors that cause treatment failure.

NCT ID: NCT02208323 Completed - Hypoxia Clinical Trials

Advancement of Modified Bubble CPAP

Start date: July 2015
Phase: Phase 2
Study type: Interventional

This study proposes that modifying the current form of bCPAP by adjusting the nasal prongs to fit older children, will create a safe form of respiratory support that may help to decrease respiratory distress and thus mortality from pneumonia.

NCT ID: NCT02000674 Completed - Shock Clinical Trials

Succinylcholine vs Rocuronium for Prehospital Emergency Intubation

CURASMUR
Start date: December 2013
Phase: Phase 3
Study type: Interventional

All adult patients with spontaneous cardiac activity and requiring tracheal intubation in the pre hospital emergency context will be included in order to compare the use of succinylcholine vs Rocuronium for prehospital emergency intubation.

NCT ID: NCT01310153 Completed - Clinical trials for Transient Tachypnea of the Newborn

Effect of Supine or Prone Position After Caesarean Birth

Start date: September 2006
Phase: N/A
Study type: Interventional

Respiratory Distress is a frequent clinical diagnosis of babies delivered by elective Caesarean birth. There has been no study comparing the efficacy of immediately positioning a newly born infant prone vs. supine for the first 30 60 seconds of life after delivery by Caesarean birth.

NCT ID: NCT00889772 Completed - Acute Lung Injury Clinical Trials

Lung Injury Prediction Study

USCTG-LIPS1
Start date: March 2009
Phase: N/A
Study type: Observational

The purpose of the study is to externally validate the acute lung injury/acute respiratory distress syndrome (ALI/ARDS) prediction model (Lung Injury Prediction Score - LIPS) in a multicenter sample of patients at risk presented to the acute care hospitals: United States Critical Illness and Injury Trials Group (USCIITG).

NCT ID: NCT00644722 Completed - Cardiac Arrest Clinical Trials

Out-of-Hospital Intubation With Metal Single Use Laryngoscope Blades

LAMETA
Start date: April 2008
Phase: Phase 4
Study type: Interventional

New single use laryngoscope metal blades are available for intubation. This type of blade is safer than the reusable ones concerning the interhuman cross infection risk. No clinical studies have compared the two types of blades in the emergency context. The primary aim of this study is to demonstrate that single use blades are as efficient as the reusable ones concerning intubation conditions.

NCT ID: NCT00513890 Completed - Bronchiolitis Clinical Trials

Interest of Non Invasive Ventilation Versus Oxygen During the Intial Managment of Infant With Bronchiolitis

Start date: October 2006
Phase: N/A
Study type: Interventional

The purpose of the study is to evaluate, in a prospective way, the clinical, the manometric an gazometric benefit of non-invasive ventilation (VNI), (INFANTFLOW [EME, Brighton, England]) during bronchiolitis of the infant compared to a conventional managment.

NCT ID: NCT00356902 Completed - Prematurity Clinical Trials

Comparison of Different Oxygen Delivery Strategies During Resuscitation of Babies

Start date: July 2005
Phase: N/A
Study type: Interventional

Preterm infants are born with immature lungs and often require help with breathing shortly after birth. This currently involves administering 100% oxygen. Unfortunately, delivery of high oxygen concentrations leads to the production of free radicals that can injure many organ systems. Term and near-term newborns deprived of oxygen during or prior to birth respond as well or better to resuscitation with room air (21% oxygen) compared to 100% oxygen. However, a static concentration of 21% oxygen may be inappropriate for preterm infants with lung disease. Our study will investigate how adjusting the amount of oxygen given to sick preterm newborns will affect the ability to maintain a safe oxygen level in their blood. Each infant will be assigned to receive one of three treatments at birth. Resuscitation will either start with 21% oxygen and be increased if needed, 100% oxygen and be decreased if needed or 100% oxygen with no changes made (current standard of treatment). The first two groups will have adjustments in oxygen concentration as needed to reach a safe target range of blood oxygen saturation. We anticipate that preterm newborn infants resuscitated with higher oxygen concentrations will have higher than "normal" levels of oxygen in their blood while those resuscitated initially with lower concentrations of oxygen will be more likely to have "normal" oxygen levels in their blood. All premature infants will have a surface probe placed on the right hand to measure the saturation of blood with oxygen. Following the resuscitation, treatment will proceed as per standard of care until hospital discharge. All infants will be admitted to the neonatal intensive care unit given their prematurity. The purpose of this study is to investigate how safely restricting the amount of oxygen delivered to newborns during resuscitation will affect the amount of oxygen in their blood. Hypothesis: In this randomized control trial, infants resuscitated with a "low oxygen delivery (LOD)" strategy (initiation of resuscitation with 21% O2) will remain normoxemic for the greatest proportion of time during resuscitation and infants resuscitated with a "high oxygen delivery (HOD)" strategy (100% O2 used for the entire resuscitation) will be normoxemic for the smallest proportion of time during resuscitation.

NCT ID: NCT00322660 Completed - Hypoglycemia Clinical Trials

Adrenaline Injections to Children Born at Elective CS

Start date: June 2006
Phase: N/A
Study type: Interventional

Children born after elective C-section have a greater risk of respiratory problems and hypoglycemia - most likely due to a lower concentration of stress hormones compared to children born vaginally. Hypothesis: can we eliminate or reduce the risk of respiratory distress and hypoglycaemia by administrating adrenaline to the newborn.