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Postoperative Complications clinical trials

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NCT ID: NCT05794269 Recruiting - Quality of Life Clinical Trials

Turkish Version of the QoR-15 for Emergency Laparotomy

QoR-15T-EL
Start date: February 1, 2023
Phase:
Study type: Observational

Patient perceived quality of recovery is an important outcome after surgery and should be measured in clinical trials. The QoR-15 was designed to measure quality of recovery postoperatively. It provided an efficient evaluation of the postoperative quality of recovery. The primary objectives of this study is validate the Turkish version of QoR-15 questionnaire for emergency laparotomy. The investigators will test its validity, reliability, responsiveness, and clinical acceptability and feasibility, with patients emergency laparotomy, in the University of Health Sciences, Gülhane Education and Training Hospital Ankara, Türkiye.

NCT ID: NCT05793203 Recruiting - Liver Dysfunction Clinical Trials

Single-center Prospective Study of Non-invasive Methods for the Diagnosis of Postoperative Complications in Liver Transplant Recipients

ElastOLT
Start date: July 6, 2020
Phase:
Study type: Observational

A lot of different early and late complications may occur after liver transplantation. They could be related to surgical procedure, to infectious diseases or immuno-mediated diseases (acute cellular rejection, ACR). Almost all of those complications are characterized by an elevation in liver enzymes (ALT, AST and GGT) and a decline of liver function tests (serum bilirubin and INR increase) possibly leading to early allograft disfunction (EAD). In this scenario there is a lack of biomarker that could predict the development of ACR and/or EAD. The aim of this study is to explore the prognostic role of non-invasive instrumental and biological marker in the early post-transplant phase.

NCT ID: NCT05788718 Recruiting - Anesthesia Clinical Trials

An Observational Study to Analyze the Prescription Pattern of Sugammadex and Its Effectiveness and Safety

SECURE
Start date: April 11, 2023
Phase:
Study type: Observational

The purpose of this observational study is to evaluate patients who are planning to administer sugammadex after rocuronium or vecuronium is used. The main questions it aims to answer are: 1. Prescription pattern of sugammadex 2. Effectiveness and safety of sugammadex Since this study is observational, only data generated under daily treatment are to be collected, and no additional tests or drug administration is conducted for the study. The patients are observed from baseline to 24 hours after the initial administration of sugammadex.

NCT ID: NCT05755230 Recruiting - Clinical trials for Perioperative/Postoperative Complications

Prospective Cohort of Perioperative Results

Start date: January 1, 2023
Phase:
Study type: Observational [Patient Registry]

Perioperative online register of the care process and outcomes. Observational prospective cohort.

NCT ID: NCT05754268 Recruiting - Clinical trials for Postoperative Complications

Establishment, Verification and Clinical Application of Chinese Version of Surgical Risk Assessment System

CSRAS
Start date: January 1, 2022
Phase:
Study type: Observational

The goal of this observational study is to establish and verify the Chinese version of surgical risk assessment system and explore its clinical application. The main questions it aims to answer are: The process of establishing a Chinese version of surgical risk assessment system; What is the accuracy of the system; How can the system be used in clinic; How does this system compare with other systems (such as NSQIP). Participants will comprehensively collect the general information, examination and pathological information of the patients, using machine learning and artificial intelligence methods for data processing. Finally, the Chinese version of the surgical risk assessment system will be established. After the system is established, investigators will evaluate the accuracy of the system and compare it with other related systems.

NCT ID: NCT05752162 Recruiting - COVID-19 Clinical Trials

Perioperative Complications Linked to COVID-19 History in Elective Cardiac Surgery Patients

Start date: July 20, 2022
Phase:
Study type: Observational [Patient Registry]

A. Primary objective Identifying risk factors for peri-operative complications in patients who have had COVID-19. B. Secondary objectives Identifying peri-operative complications in patients who have had COVID-19. Follow-up of peri-operative complications during hospitalization. Identifying the safe distance at which a patient can be operated after a Sars CoV2 infection without having an increased risk of peri-operative complications. C. Study inclusion and exclusion criteria 1. Inclusion criteria Patients should be included if: - are scheduled for elective cardiac surgery with extracorporeal circulation (bypass); - they give their consent for their data to be included in studies; 2. Exclusion criteria Patients should be excluded if: - they have emergency surgery; - have had Sars Cov 2 infection more recently than 3 months; D. Data Collection It is done in an excel table. Data collection is done anonymously. No patient-identifying data will be collected. The collected data will be about comorbidities, COVID-19 status - disease and vaccination, postoperative complications.

NCT ID: NCT05743673 Recruiting - Clinical trials for Perioperative/Postoperative Complications

SHAPE Test for Preoperative Risk Stratification

SHAPEPAT
Start date: May 3, 2023
Phase:
Study type: Observational

Primary Objective Characterizing precise functional capacity in surgical patients is critical for risk stratification and identification of patients at high risk for perioperative complications. The primary objective for the study is to evaluate the feasibility of effective subject recruitment of an FDA-approved simplified cardiopulmonary exercise testing apparatus in adults >60 years old prior to moderate to high-risk surgery. In addition, by development of a validation cohort of older adults, defined as >60 years old, self-reporting >4 METS and with a score of <2 on the revised cardiac risk index (RCRI)1 we will compare its effectiveness when compared to conventional preoperative evaluation measures (METS determination by standard scoring and Duke Activity Status Index) to SHAPE™ testing.

NCT ID: NCT05738603 Recruiting - Clinical trials for Head and Neck Cancer

The Hypotension Prediction Index in Free Flap Transplant in Head and Neck Surgery.

Start date: March 1, 2023
Phase: N/A
Study type: Interventional

The aim of the current study is to evaluate the effects of the Hypotension Prediction Index (HPI) on the degree of intraoperative hypotension in patients undergoing free flap surgery. The hypothesis is that implementation of the HPI algorithm will reduce the time-weighted average (TWA) intraoperative hypotension below a threshold of 65 mmHg (16), and to reveal the relationship between the episodes of hypotension and free flap viability and function.

NCT ID: NCT05732116 Recruiting - COVID-19 Clinical Trials

PTSD of Surgeons or Anesthesiologists on Prognosis of Surgical Patients

Start date: February 21, 2023
Phase:
Study type: Observational

The objective of this prospective cohort study is to explore the association between the development of post-traumatic stress disorder (PTSD) in surgeons and anesthesiologists and postoperative prognosis in surgical patients they care for during the COVID-19 pandemic. There are 2 cohorts included in this study. The first cohort consists of registered surgeons and anesthesiologists in the study center. The development of PTSD will be evaluated with a series of questionnaires and scales. This cohort defines exposure (with PTSD). The second cohort consists of surgical patients managed by the surgeons and anesthesiologists in the first cohort. The postoperative outcome of these patients will be evaluated thus to explore the association between PTSD in physicians and adverse patient outcomes. The second cohort defines the outcomes( response).

NCT ID: NCT05728645 Recruiting - Clinical trials for Postoperative Complications

Colloid Infusion for Optimal Outcomes In Non-cardiac Surgery (COIN Trial)

COIN
Start date: July 12, 2023
Phase: N/A
Study type: Interventional

Hypotension is associated with postoperative complications. Preoperative fluid infusion can effectively prevent post-induction hypotension of general anesthesia. Previous studies only focused on the hemodynamics after preoperative fluid infusion. Pre-operative fluid infusion can reduce the incidence of post-operative complications by preventing post-induction hypotension. The patients who is 18 years or older and undergo elective non-cardiac surgery with general anesthsia will be enrolled. The intervention is intravenous infusion of colloids or crytalloids before induction of general anesthesia. The primary outcome is the incidence of post-operative complications within 30 days.