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Postoperative Complications clinical trials

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NCT ID: NCT05939193 Recruiting - Acute Kidney Injury Clinical Trials

Effect of Urine-guided Hydration on Acute Kidney Injury After CRS-HIPEC

Start date: July 24, 2023
Phase: N/A
Study type: Interventional

Acute renal injury (AKI) is a common complication after cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy (CRS-HIPEC), and is associated with worse outcomes. Available evidences show that maintaining intraoperative urine output ≥ 200 ml/h by fluid and furosemide administration may reduce the incidence of AKI in patients undergoing cardiopulmonary bypass. The investigators hypothesize that, for patients undergoing CRS-HIPEC, intraoperative urine-volume guided hydration may also reduce the incidence of postoperative AKI.

NCT ID: NCT05910281 Recruiting - Postoperative Pain Clinical Trials

Rebound Pain and Related Factors in Postoperative Patients With Total Knee Arthroplasty

Start date: July 1, 2023
Phase:
Study type: Observational [Patient Registry]

The aim of this prospective observational study is to detect rebound pain and related factors in postoperative patients with total knee arthroplasty.

NCT ID: NCT05906134 Recruiting - Clinical trials for Postoperative Complications

Minimally Invasive Esophagectomy Pain Control Trial

Start date: April 26, 2022
Phase: Phase 1/Phase 2
Study type: Interventional

A pilot randomized controlled trial comparing intercostal nerve blocks, cryo-ablation plus intercostal nerve blocks, and serratus plane catheter plus intercostal nerve blocks in patients undergoing esophagectomies with minimally invasive thoracic approaches.

NCT ID: NCT05893342 Recruiting - Frailty Clinical Trials

Frailty in the Perioperative Period

Frail-Negrin
Start date: June 1, 2023
Phase:
Study type: Observational

The presence of frailty is associated with a high risk of complications in the perioperative period, increasing morbidity and mortality, hospital stay, and loss of quality of life. In this prospective observational study, an evaluation of frailty was performed in patients older than 65 years old who undergo scheduled and urgent surgery. 100 patients are being included for 3 months. The main objective is to evaluate the prevalence of frailty in patients older than 65 years undergoing surgery in our hospital and its association with postoperative mortality.

NCT ID: NCT05890820 Recruiting - Lung Cancer Clinical Trials

The Effect of Nutritional Risk Parameters on Postoperative Pulmonary Complications in Geriatric Thoracic Surgery Cases

Start date: May 30, 2023
Phase:
Study type: Observational [Patient Registry]

Preoperative evaluation of nutritional status in geriatric patients with lung cancer and implementation of these practices in elective patients are very important in terms of reducing postoperative complications and accelerating hospital discharge. For this purpose, many nutritional assessments and measurements are used. Our aim in this study was to evaluate the relationship between preoperative nutritional status and postoperative pulmonary complications in patients undergoing thoracic surgery for geriatric lung cancer.

NCT ID: NCT05867043 Recruiting - Surgery Clinical Trials

Postoperative Gastrointestinal Dysfunction After High Risk Surgery

Start date: January 23, 2023
Phase:
Study type: Observational

This study aims to find out the role of plasma I-FABP level, SOFA score, fluid balance, and vasopressor dose in predicting gastrointestinal dysfunction in high-risk postoperative patients treated in ICU

NCT ID: NCT05861089 Recruiting - Clinical trials for Post-Op Complication

Rest PETCO2 as a Predictor of Post-operative Complications

Start date: June 1, 2023
Phase:
Study type: Observational

Cardiopulmonary exercise testing (CPET) is considered to be a golden standard in preoperative risk assessment and stratification of high risk patients scheduled for major surgery. However, not all of the patients requiring surgery are willing or able to complete this type of testing. Vascular surgery patients are predominantly elderly people, with significant comorbidity and high degree of frailty and often can not undergo CPET. In recent years, new parameters with similar prognostic value as standard CPET parameters were studied. Specifically, the partial pressure of end-tidal carbon dioxide (PETCO2) at rest has been shown to have the same prognostic value as ventilatory efficiency. We hypothesized low PETCO2 at rest will be associated with the development of pulmonary and cardiovascular post-operative complications in patients after major vascular surgery. Accordingly, our aim is to compare PETCO2 measured at rest before surgery in patients who develop post-operative complications and in those who do not.

NCT ID: NCT05843383 Recruiting - Clinical trials for Postoperative Complications

Comparison of Ciprofol-based and Propofol-based Total Intravenous Anesthesia on Postoperative Quality of Recovery

Start date: May 16, 2023
Phase: N/A
Study type: Interventional

Ciprofol is a novel 2,6-disubstituted phenol derivatives and is proved have much higher potency and tighter binding toward ɣ-aminobutyric acid type A (GABAA) receptor while maintaining a fast on-set and recovery time compared to propofol. Except lower incidence of hypotension and respiratory depression, it has no injection pain and infusion syndrome compared with propofol. There is no study to investigate overall postoperative functional recovery in patients receiving total intravenous anesthesia (TIVA) using ciprofol yet. However, according to study, early quality of recovery according to QoR-15 score is associated with one-month postoperative complications after elective surgery. Therefore, the purpose of this study is to determine whether there is any difference in the quality of postoperative recovery between ciprofol-based and propofol-based TIVA in elderly patients undergoing gastrointestinal surgery. The QoR-15 questionnaire score, pain, nausea/vomiting, and the frequency of complications are evaluated and compared between the two groups.

NCT ID: NCT05824260 Recruiting - Clinical trials for Postoperative Morbidity

Risk Factors for Postoperative Complications in Major Non-cardiac Surgery: Post-hoc Analysis of the OPHIQUE Multicentre Study

MULTIPAS
Start date: June 23, 2022
Phase:
Study type: Observational

Post-operative morbidity and mortality is related to many factors related to the patient's condition, the intra-operative period and the optimisation of intra-operative haemodynamic and respiratory parameters. Many studies have looked at the determinants and factors that increase postoperative complications. However, these have been randomised studies looking at one parameter in particular. This analysis would be the first to investigate the determinants of postoperative complications in a large population of patients undergoing major non-cardiac surgery. This is a post-hoc analysis of patients included in the OPHIQUE study, whose main objective was to evaluate intraoperative haemodynamic management guided by a marker of tissue hypoperfusion (the respiratory quotient).

NCT ID: NCT05818163 Recruiting - Pain Clinical Trials

Association of Perioperative Electroencephalography Spectral Analysis With Postoperative Complications

Start date: May 2023
Phase:
Study type: Observational [Patient Registry]

Using data from electroencephalogram (EEG) obtained through intraoperative depth of anesthesia monitoring devices, combined with clinical symptoms such as postoperative pain and delirium, investigate their correlation and verify whether intraoperative EEG spectral analysis can predict the occurrence of postoperative pain, nausea and vomiting, restlessness, or delirium in patients undergoing surgery.