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Paralysis clinical trials

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NCT ID: NCT05213039 Completed - Cerebral Palsy Clinical Trials

Validity and Reliability of the the Timed 360° Turn Test

cp
Start date: July 15, 2022
Phase:
Study type: Observational [Patient Registry]

Cerebral Palsy (CP) is a non-progressive neurodevelopmental disorder that starts in the early stages of life, causes activity limitation, and consists of movement and posture deficiencies. Children with CP usually have difficulties in mobility, transfer and social participation due to many motor and sensory disorders such as muscle weakness, decreased postural control, balance, spasticity. Many children with CP have difficulty in balancing independently, walking, walking on hills/uneven ground, and performing daily physical functions.

NCT ID: NCT05212415 Completed - Cerebral Palsy Clinical Trials

Bruxism and Parafunctional Oral Habits in Children and Adolescents With Cerebral Palsy

Start date: January 7, 2020
Phase:
Study type: Observational

The aim of the study is to evaluate and analyze the rates and relationships between bruxism, other parafunctional oral activities, and oral-motor activities in children and adolescents with spastic CP.

NCT ID: NCT05209282 Completed - Clinical trials for Diplegic Cerebral Palsy

Diplegic Cerebral Palsy and Action Observation Training

Start date: January 1, 2022
Phase: N/A
Study type: Interventional

In this study, video-based action observation training and live action observation training in children with spastic diplegic cerebral palsy; It was aimed to examine the effect on motor function, activity participation and secondary outcome measures.

NCT ID: NCT05206513 Recruiting - Cerebral Palsy Clinical Trials

Study to Assess the Efficacy, Safety, and Tolerability of Valbenazine for the Treatment of Dyskinesia Due to Cerebral Palsy

Start date: April 15, 2022
Phase: Phase 3
Study type: Interventional

The primary objective of this study is to evaluate the efficacy of valbenazine versus placebo on improving chorea in participants aged 6 to 70 years who have dyskinesia due to cerebral palsy (DCP) with choreiform movements.

NCT ID: NCT05202028 Active, not recruiting - Cerebral Palsy Clinical Trials

The Efficacy of Massage and Reflexology Applications in Children With Cerebral Palsy

Start date: November 5, 2021
Phase: N/A
Study type: Interventional

The study aims to compare the effectiveness of classical massage, connective tissue massage, and reflexology in children with cerebral palsy.

NCT ID: NCT05198999 Completed - Cerebral Palsy Clinical Trials

Aquatic-based Explosive Strength Training in Children With Cerebral Palsy

Start date: August 6, 2018
Phase: N/A
Study type: Interventional

This study was designed to assess the effect of a 12-week aquatic-based plyometric (Aqua-PLYO) training on postural control and functional performance in children with hemiparetic cerebral palsy (h-CP). Fifty-six children with h-CP were randomly allocated to the Aqua-PLYO group (n = 28, received an Aqua-PLYO training program, trice/week, over 12 weeks) or the control group (n =28, received standard rehabilitation). Both groups were assessed for postural control and functional performance pre and post-treatment.

NCT ID: NCT05197764 Recruiting - Clinical trials for Acquired Brain Injury

Evaluation of Macroscopic Muscle Growth in Infants and Young Children With Spastic Cerebral Palsy

3D-MMAP
Start date: February 11, 2019
Phase:
Study type: Observational

A mixed longitudinal design study will be carried out to explore the onset and time course of morphological muscle changes on a macroscopic level in children with spastic cerebral palsy (SCP). Therefore, this project aims to (1) describe the macroscopic morphological muscle changes with increasing age and (2) evaluate the onset and development of muscle alterations in relation to the brain lesion (e.g., timing, extent and location), to the neuromuscular impairments and to treatment. Overall, this project will evaluate the macroscopic muscle properties by means of 3D freehand ultrasound (3DfUS).

NCT ID: NCT05194319 Completed - Quality of Life Clinical Trials

Effect of Upper Extremity Functional Skills on Quality of Life and Participation of the Children With Cerebral Palsy

CP
Start date: November 15, 2021
Phase:
Study type: Observational [Patient Registry]

Cerebral palsy (CP) is a movement and posture disorder accompanied by sensory, perception, cognition, communication and behavioral disorders that cause activity limitations by causing various non-progressive disorders of the fetal or infant brain. Spastic CP, according to the affected area in the body; It is classified as hemiparetic, diparetic and is observed most frequently. Diparetic CP, on the other hand, is characterized by significant spasticity in the pelvis and lower extremities, mild hypertonus or spasticity in the upper extremities, and incoordination, mostly involving the lower extremities and some upper extremities.Although lower extremity involvement is observed in different degrees in children with diparetic CP, studies showing how upper extremity and hand functions are affected are insufficient.The aim of this study is to compare the effect of upper extremity functional skills on quality of life and participation levels in children with diparetic CP with their healthy peers.

NCT ID: NCT05193240 Not yet recruiting - Clinical trials for Adults Patients Undergoing Major Lung Resection in the Context of Lung Cancer

Predictive Value of a Preliminary Swallowing Test Compared to Postoperative Nasofibroscopy to Identify Vocal Cord Paralysis After Pulmonary Resection

SwaLO
Start date: May 2022
Phase: N/A
Study type: Interventional

The literature describes recurrent nerve damage during thoracic surgery as a fairly complication (5 to 31% of patients). This nerve damage leads to paresis or paralysis of the ipsilateral vocal cord. This cord dysfunction no longer ensures the protective role of the airways during swallowing. This postoperative dysphagia is associated with complications such as aspiration pneumonia, the use of nasogastric tube feeding (adding difficulty to swallowing), delayed oral refeeding (risk of undernutrition, dehydration, decrease in the quality of life), and an increase in the length of hospitalization and mortality. Identifying these patients at risk is essential to limit complications (pneumonia, reintubation, inadequate refeeding, etc.). The benchmark test to objectify vocal cord palsy is to perform a nasofibroscopy requiring equipment and the intervention of an ENT doctor or thoracic surgeon. A physiotherapist can also perform a preliminary swallowing test by evaluating several criteria. The aim of this study is to compare the concordance of results between nasofibroscopy and that by preliminary swallowing test, two procedures performed in the screening of vocal cord paralysis in a surgical intensive care unit and a thoracic surgery ward. Patients will be included before the surgery. During this inclusion visit, we will perform a preoperative swallowing test. Immediately after surgery (H2-H24 after extubation), we will perform a preliminary swallowing test, an ultrasound examination of the vocal cords and a nasofibroscopy to determine the mobility of the vocal cords. A physiotherapist will carry out the first two assessments. An ENT physician will perform the nasofibroscopy. The ENT physician performing the nasofibroscopy will not know the conclusions of the tests carried out by the physiotherapist immediately after the operation. At last, on day 4 after extubation, we will repeat the preliminary swallowing test and the ultrasound examination to measure the evolution of cord mobility. Initial evaluation and secondary evaluation (day 4) will be performed by two different physiotherapists in order to allow blinding between the two stages of the procedure. 45 days after the surgery, we will realize a follow-up on medical file and mark the end of the research. We want to include 72 patients over an 18 months period.

NCT ID: NCT05191719 Recruiting - Bell Palsy Clinical Trials

Neurotomy to Treat Synkinesis Following Peripheral Facial Palsy

Start date: February 1, 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate neurotomy as an alternative treatment to Botox injections for severe synkinesis following peripheral facial palsy