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Paralysis clinical trials

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NCT ID: NCT06337877 Active, not recruiting - Clinical trials for Sedation Complication

Assessment of Sedation Depth in ARDS Patients Undergoing Therapeutic Paralysis

Start date: October 1, 2023
Phase:
Study type: Observational

"In intensive care units, therapeutic paralysis has been a routine treatment method for many years in a select group of patients. Sufficient and appropriate sedation in patients undergoing therapeutic paralysis is crucial to prevent awareness and reduce the risk of excessive sedation. Both inadequate and excessive sedation levels can be highly detrimental to the patient. Clinical assessment may not always provide accurate information regarding sedation depth. Recently, the frequency and workload of therapeutic paralysis treatment in intensive care units have increased due to COVID-19 pneumonia. Therefore, the investigators believe that inadequate sedation may be common in these patients. Processed electroencephalogram parameters such as bispectral index or patient state index (PSI), routinely used in operating rooms and intensive care units, are commonly used to indicate sedation depth. In this study, the investigators aimed to determine sedation levels in patients during paralysis, assess the prevalence of inadequate or excessive sedation, and observe the doses of sedatives and analgesics used."

NCT ID: NCT06257589 Active, not recruiting - Clinical trials for Diaphragmatic Paralysis

A Chart Review to Evaluate the Safety and Efficacy of Phrenic Nerve Reconstruction for the Treatment of Diaphragmatic Paralysis

Start date: October 10, 2023
Phase:
Study type: Observational

A retrospective chart review to evaluate the safety and efficacy of phrenic nerve reconstruction for diaphragmatic paralysis.

NCT ID: NCT06146179 Active, not recruiting - Clinical trials for Diaphragmatic Paralysis

Combined Anterior Suprascapular Nerve Block and Superficial Cervical Plexus Block In Shoulder Arthroplasty Surgery

Start date: November 1, 2023
Phase:
Study type: Observational

The suprascapular nerve, originating from the C5 trunk, provides innervation to the acromioclavicular and glenohumeral joints. The supraclavicular nerve, a branch of the cervical plexus, contributes to the sensory innervation of the upper deltoid region. Cervical and brachial plexus blocks can cause diaphragm paralysis. This study examined the effects of low-volume combined anterior suprascapular nerve block and superficial cervical plexus block on pain and phrenic nerve in participants underwent reverse shoulder arthroplasty surgery.

NCT ID: NCT06051422 Active, not recruiting - Clinical trials for Correlation of Pelvic Asymmetry and Joint Movement During Gait in Children With Cerebral Palsy

Correlation of Pelvic Asymmetry and Joint Movement During Gait in Children With Cerebral Palsy

Start date: February 12, 2023
Phase:
Study type: Observational

the study's particular goals were to determine whether excessive hip, knee, and ankle displacement at first contact during locomotion correlates with pelvic rotation.

NCT ID: NCT05997199 Active, not recruiting - Clinical trials for Vitamin D Deficiency

The Effect Vitamin D on the Recovery Rate of Bell Palsy

Start date: June 1, 2023
Phase:
Study type: Observational

Patients aged between 18-65 who visit the Physical Medicine and Rehabilitation outpatient clinic diagnosed with Bell Palsy will be included in the study. The patients' Bell Palsy grade will be evaluated by Houseman Brahman (HB) Scale and their disability level will be evaluated by Facial Disability Index (FDI). Their serum vitamin D level will be noted. The patients having vitamin D deficiency will be randomized into two groups. Group 1 will be given 50.000 IU/week vitamin D replacement for 8 weeks. All the patients will be included in a standard physical therapy and home exercise program. Both groups will be asked for a control visit at weeks 8.Their clinical recovery will be evaluated by HB staging and FDI by the Physical Medicine and Rehabilitation specialist who is blind to the randomization.

NCT ID: NCT05473182 Active, not recruiting - Cerebral Palsy Clinical Trials

IndieTrainer: Enabling Individuals With Cerebral Palsy to Receive Gamified Power Mobility Training in Their Own Manual Wheelchairs

Start date: August 15, 2022
Phase: N/A
Study type: Interventional

Power wheelchairs (PWCs) offer children who are unable to independently opportunities for participation in social, educational, and leisure activities. Unfortunately, children who have severe cognitive, motor, or sensory impairments may need extended training to be able to master the PWC skills needed to "qualify" for their own PWC. The IndieTrainer system was developed to address this need. The IndieTrainer system is comprised of the IndieGo device and video-game modules. The IndieGo device temporarily converts a manual wheelchair into a powered wheelchair, thereby allowing children to remain in their own manual wheelchair and use their own custom seating system during power wheelchair skills training activities. The video-game modules are integrated into the IndieGo device such that the video games can be played on a TV screen using the specific access method used to control the IndieGo (i.e., switch or joystick). The IndieTrainer system is designed to allow a child to practice power wheelchair skills as part of the video-game modules or as part of more traditional power wheelchair skills training activities wherein children are able to actively explore the environment and practice executing actual wheelchair skills. This study will evaluate the use of the IndieTrainer system in children with cerebral palsy, ages 5-21 years.

NCT ID: NCT05202028 Active, not recruiting - Cerebral Palsy Clinical Trials

The Efficacy of Massage and Reflexology Applications in Children With Cerebral Palsy

Start date: November 5, 2021
Phase: N/A
Study type: Interventional

The study aims to compare the effectiveness of classical massage, connective tissue massage, and reflexology in children with cerebral palsy.

NCT ID: NCT05035823 Active, not recruiting - Clinical trials for Spinal Cord Injuries

COMMAND Early Feasibility Study: Implantable BCI to Control a Digital Device for People With Paralysis

Start date: April 27, 2022
Phase: N/A
Study type: Interventional

The Synchron motor neuroprosthesis (MNP) is intended to be used in subjects with severe motor impairment, unresponsive to medical or rehabilitative therapy and a persistent functioning motor cortex. The purpose of this research is to evaluate safety and feasibility. The MNP is a type of implantable brain computer interface which bypasses dysfunctional motor neurons. The device is designed to restore the transmission of neural signal from the cerebral cortex utilized for neuromuscular control of digital devices, resulting in a successful execution of non-mechanical digital commands.

NCT ID: NCT04957277 Active, not recruiting - Cerebral Palsy Clinical Trials

Stepping to Understand Lower Limb Impairments in Bilateral Cerebral Palsy

Start date: May 19, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate lower limb impairments in children with bilateral cerebral palsy during stepping tasks.

NCT ID: NCT04835753 Active, not recruiting - Cerebral Palsy Clinical Trials

Shock Wave and Spastic Cerebral Palsy Equines Foot

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Start date: January 1, 2021
Phase: N/A
Study type: Interventional

A double-blind randomized controlled study was carried out on 34 children (19 boys and 15 girls) in the age ranged from 7 to 9 years old with spastic hemiplegia were randomly allocated to one of two groups: control or study group. The two groups received traditional therapeutic exercises for 12 weeks. Additionally, study group received rESW (one session/week) on gastrocnemius and soleus muscles (1500 shots/muscle, frequency of 4Hz, energy of 0.030 mJ/mm2). All children were evaluated at baseline, and after 12 weeks by Modified Ashworth Scale, Biodex system 4 isokinetic dynamometer, Gross Motor Function Measure (GMFM-88), dimensions "D" standing and "E" walking, Trost Selective Motor Control Test, and Single Leg Standing Test.