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Paralysis clinical trials

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NCT ID: NCT05271149 Recruiting - Clinical trials for Diplegic Cerebral Palsy

Dynamic Orthotic Garment in Diplegic Cerebral Palsy

Start date: February 17, 2022
Phase: N/A
Study type: Interventional

This study aims to evaluate the effectiveness of dynamic orthotic garment (Thera togs) on foot pressure distribution, postural control, functional performance and endurance in children with spastic diplegic cerebral palsy (CP). Methods: forty children with spastic diplegic CP, with ages ranging from 8 to 10 years, will be assigned randomly into two groups. The control group will receive the conventional physical therapy, whereas the study group will receive the same program as the control group in addition to Thera togs. Measurement of foot pressure distribution will be performed using a pressure platform, postural control will be evaluated using the trunk control measurement scale Trunk Position Sense pediatric berg balance scale, endurance will be assessed using six-minute walk test (6MWT)

NCT ID: NCT05270187 Recruiting - Bell Palsy Clinical Trials

Multiwave Locked System Laser for Patients With Bell's Palsy.

MLS
Start date: January 10, 2022
Phase: N/A
Study type: Interventional

Background: Idiopathic Bell's palsy (IBP) is a unilateral facial paralysis of sudden onset and unknown etiology. Patient with IBP has an impaired facial expressions and psychological affection, which interfere with social communication. Multiwave locked system (MLS) laser therapy is a class IV laser with synchronizes emission of an 808 nm continuous laser and a 905 nm pulsed laser. It is proposed that MLS facilitates greater penetration and therapeutic effects than low-level laser therapy (LLLT). Aims: The aim of present study is to investigate the effect of MLS laser in the treatment of patients with unilateral IBP. Participant: A total number of 60 patients with IBP will be recruited from Makkah hospitals. Treatment will begin in the subacute phase as they referred from neuro-doctors. All the recruited patients will be randomly assigned into three groups of 20 patients each. Intervention: All patients will be treated with facial massage and exercises. In addition, group one will receive MLS laser with 10 J/cm2 in scanning mode while the group two will receive 10J/point for eight points. Measured variables: Facial disability scale (FDI) and House-Brackmann scale HBS will used to assess the grade of facial nerve recovery. The scores of both questionnaires will be collected at the baseline, after three and six weeks after treatment. Statistical Analysis: The Friedman and Wilcoxon signed ranks tests will be used to compare the FDI and HBS scores within each group

NCT ID: NCT05251532 Completed - Clinical trials for Cerebral Palsy, Spastic

The Efficacy of Distortion Banding on Outcome Measures in Children With Cerebral Palsy

Start date: March 15, 2022
Phase: N/A
Study type: Interventional

The aim of the study is to compare the conventional rehabilitation program and the distortion taping applied with Kinesio Tex tape in addition to conventional rehabilitation in children with hemiplegic or monoplegic cerebral palsy with ankle varus deformity.

NCT ID: NCT05251519 Completed - Clinical trials for Cerebral Palsy, Spastic

The Efficacy of Derotation Banding on Outcome Measures in Children With Cerebral Palsy

Start date: March 15, 2022
Phase: N/A
Study type: Interventional

The aim of the study is to compare the conventional rehabilitation program and derotation taping applied with Kinesio Tex tape in addition to conventional rehabilitation in children with hemiplegic or monoplegic cerebral palsy with femoral internal rotation deformity.

NCT ID: NCT05244408 Recruiting - Clinical trials for Spinal Cord Injuries

"SCRIBBLE" Spinal Cord Injury Blood Biomarker Longitudinal Evaluation

SCRIBBLE
Start date: March 17, 2023
Phase:
Study type: Observational

Prospective, single center study designed to assess blood biomarkers for classifying injury severity and predict neurologic recovery in traumatic spinal cord injured (SCI) patients. Study will also establish the accuracy of point to care devices for SCI blood biomarkers and support the biospecimen collection for the International Spinal Cord Injury Biobank (ISCIB).

NCT ID: NCT05244083 Enrolling by invitation - Clinical trials for Hemiplegic Cerebral Palsy

Effectiveness of the Mirror Therapy for Improving Bimanual Performance, Somatosensory Function of the Impaired Upper Limb and Quality of Life in Children With Unilateral Spastic Cerebral Palsy

Start date: January 1, 2022
Phase: N/A
Study type: Interventional

- Background: Unilateral Spastic Cerebral Palsy (USPC) is caused by an injury in one brain hemisphere in the immature brain, and affects the contralateral side of the body, especially on the upper limb. It induces motor and somatosensory damages, that are closely related to the hand function. Evidence posits mirror therapy to be a therapy with potential effects on bimanual performance and somatosensory function, that may influence on quality of life. The aim of this study is to demonstrate the effectiveness of a motor program with mirror therapy in children with USCP in the improvement of the bimanual performance, the somatosensory function and quality of life compared with the same program without mirror. - Methods: This study is a Randomised Clinical Trial. The participants are children with USCP aged between 8 and 12 years old classified in levels I and II in Manual Ability Classification System, recruited from Fundació Aspace Catalunya. The eligibility criteria are a) to not have had surgical interventions, botulinum toxin or shock waves 3 months before the study; b) to not be receiving intensive therapies on the upper limb; c) to not have attentional or behavioural difficulties; d) to not have moderate to high intellectual disability; e) to not have non-treated epilepsy; and f) to not have non-corrected visual problems. A total of 22 participants will be recruited for this study, and will be randomised in two groups: control and experimental, through the opaque envelope technique. The experimental group will perform a 5-week motor program consisting of 4 bimanual exercises with mirror therapy, to be done at home 30 minutes a day, 5 days a week, while the control group will perform the same program without the mirror. The assessments will be done by a blinded evaluator and will include bimanual performance (Children's Hand-use Experience Questionnaire), somatosensory function and quality of life (PedsQL™), and will be performed at the beginning, at the end of the intervention and 1-month follow-up. - Discussion: Favourably results in this study may imply the implementation of a low-cost therapy, suitable to be done at home, and with no contraindications for children with USCP. Moreover, the suitability to be adapted and performed at home could increase the family implication and empowerment, increasing its confidence in the disability process.

NCT ID: NCT05231538 Completed - Cerebral Palsy Clinical Trials

Neurodevelopmental Therapy for Spastic Cerebral Palsy

NDT
Start date: June 17, 2021
Phase: N/A
Study type: Interventional

This study was conducted to find out the Effects of Neurodevelopment therapy (a rehabilitative program designed by Bobath) on Gross Motor Function and Postural Control in Children with Spastic Cerebral Palsy. To investigate either there was a significant difference between the effects of neurodevelopment therapy and routine physical therapy on gross motor function and postural control in children with Spastic Cerebral Palsy.

NCT ID: NCT05229523 Completed - Cerebral Palsy Clinical Trials

Validity and Reliability of the Modified Four Square Step Test (mFSST)

cp
Start date: May 15, 2022
Phase:
Study type: Observational [Patient Registry]

Cerebral Palsy (CP) is a non-progressive neurodevelopmental disorder that causes activity limitation resulting from movement and posture deficiencies as a result of a lesion in the immature brain. Children with CP usually have difficulties in mobility, transfer and social participation due to many motor and sensory disorders such as muscle weakness, decreased postural control, balance, spasticity.Hypertonus and abnormal motor patterns, lack of trunk control and postural disorders adversely affect the physical development of these children. Children with CP show various posture disorders due to proximal muscle strength losses leading to limitations and deficiencies in postural reactions. This leads to losses in reactive and antisipatory postural adjustments, and limits upper extremity functions such as walking, reaching, and eating. For this reason, children with CP have difficulties in maintaining balance while standing or sitting independently, walking, maintaining postural control in various environments such as walking, hills/uneven floors, performing activities of daily living (ADL) and social participation.

NCT ID: NCT05222698 Not yet recruiting - Facial Paralysis Clinical Trials

Free Neurovascularized Muscle Transfer in Facial Reanimation of Long-standing Facial Palsy Patients

Start date: April 2022
Phase: N/A
Study type: Interventional

The use of free Neurovascularized muscles like free latissimus and gracillis muscles for reanimation of long-standing facial palsy patients using the hypoglossal nerve for innervating these muscles

NCT ID: NCT05213663 Completed - Cerebral Palsy Clinical Trials

Investıgatıon Of The Awareness Of The Parents Of Cerebral Palsy Children

CP
Start date: January 1, 2022
Phase:
Study type: Observational

Parents of Cerebral Palsy (CP) children participate in treatments, education services and general medical check-ups; They have many responsibilities such as the use of drugs, devices, educational materials. Therefore, involving parents of CP children in the rehabilitation process provides a stronger rehabilitation service for their children. In the studies, it was stated that the active participation of the parents in the physiotherapy and rehabilitation process increases the success rate of the treatment and the participation of the parents plays a key role for the success of the physiotherapy and rehabilitation.