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Pain clinical trials

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NCT ID: NCT05421962 Completed - Pain Clinical Trials

Analgosedation for Elective Colonoscopy

Start date: January 1, 2020
Phase: Phase 1
Study type: Interventional

Aim: The aim of the study was to to compare the analgesic effects of ketamine over fentanyl combined with propofol in analgesia-based elective colonoscopy with purpose of patient safety and satisfaction. Methods: This is a double-blinded prospective randomized controlled trial. Ninety patients were included and randomized to either fentanyl-propofol (Group FP, n: 30), ketamine-propofol (Group KP, n: 30) or propofol-control group (Group C, n: 30). Group FP patients received fentanyl and propofol, Group KP received ketamine and propofol and Group C, propofol. In all groups, incremental doses of propofol were used to maintain a Ramsay sedation score (RSS) of 5. Respiratory depression, hemodynamic parameters were monitored for the first minute and every 5 minutes during endoscopy. Fifteen minutes after the procedure, the degree of pain was assessed using a visual analog scale (VAS), the quality of recovery according to the Aldrete score (ARS), complications during and after the procedure and additional doses of propofol were recorded.

NCT ID: NCT05418712 Completed - Pain Clinical Trials

A Microneurography (MNG) Study of VX-150 in Healthy Participants

Start date: June 16, 2022
Phase: Phase 1
Study type: Interventional

The purpose of this study is to determine if C fiber conduction is impacted by NAV1.8 modulation.

NCT ID: NCT05417724 Completed - Pain Clinical Trials

Utilizing Battlefield Acupuncture(BFA) to Treat Chronic Pain for Homeless and at Risk Veterans.

Start date: March 28, 2022
Phase: N/A
Study type: Interventional

This research study will evaluate the effectiveness of utilizing Battlefield Acupuncture (BFA) on homeless and at risk for homelessness veterans with chronic pain for 12 weeks.

NCT ID: NCT05412719 Completed - Pain Clinical Trials

The Effect Of Finger Pupiling On Pain And Physiological Parameters in İnfants

Start date: February 1, 2021
Phase: N/A
Study type: Interventional

. In this determined, it was carried out to determine the effect of finger puppet play on pain and physiological parameters during urine culture with urinary catheter in infants. Research Hypotheses and Variables H0: There is no difference between the pain levels of babies who were manipulated with finger puppets during urine culture sampling with urinary catheter compared to babies in the control group. H1: Babies whose finger puppet is played during urine culture sampling with urinary catheter have low pain levels. H2: Physiological parameters of babies who are played with finger puppets during urine culture sample collection with urinary catheter are positively affected.

NCT ID: NCT05408741 Completed - Pain Clinical Trials

A Pilot Study Assessing the Effectiveness of Use of Guided Imagery for Treatment of Pain and Symptom Management in Women With Post-mastectomy Pain Syndrome

Start date: June 6, 2022
Phase: N/A
Study type: Interventional

To learn if using guided imagery and deep breathing techniques can help with pain management in patients who have post-mastectomy pain syndrome.

NCT ID: NCT05395208 Completed - Pain Clinical Trials

The Effect Of White Noise And Therapeutic Touch On Pain And Physiological Parameters In Premature Infants

Start date: June 1, 2021
Phase: N/A
Study type: Interventional

Newborns hospitalized with some respiratory problems in the clinic are taken to noninvasive mechanical ventilation support and vascular access is required for some treatments to be applied to these newborns. The presence of nasal cannulas used for noninvasive mechanical ventilation support in newborns causes restlessness, agitation and stress in infants. The uneasiness and stress experienced by babies during vascular access also affects effective vascular access, causing other doses to be delayed or skipped due to treatment doses that are not completed on time. In addition, the pain experienced by babies indirectly affects nurses. It has been reported in many studies that it is effective in reducing the pain experienced by newborns with non-pharmacological methods. Simultaneous white noise will be played and therapeutic touch applied to help touch methods and white noise listening help reduce or control newborns' pain. Many studies have shown that touching to and listening white noise is effective in reducing pain. This study was planned as a randomized controlled experimental study to determine the effect of white noise-accompanied therapeutic touch application on pain level and physiological parameters and noninvasive mechanical ventilation support during peripheral intravenous catheterization in premature infants hospitalized for treatment. Hypothesis 0: The application of therapeutic touch with white noise during peripheral intravenous catheter intervention in premature infants has no effect on the level of pain. Hypothesis 1: White noise-accompanied therapeutic touch application reduces pain level during peripheral intravenous catheter intervention in premature infants. Hypothesis 2: The therapeutic touch application accompanied by white noise during peripheral intravenous catheter intervention in premature infants positively affects physiological parameters.

NCT ID: NCT05393414 Completed - Pain Clinical Trials

Efficacy of NSAID and Acetaminophen in the Control of Post-Operative Pain in Patients Undergoing Total Knee Replacement

Start date: November 25, 2019
Phase: N/A
Study type: Interventional

An alternate perioperative pain control protocol composed of intravenous ketorolac and oral acetaminophen for patients who underwent total knee replacement was designed with the aim to determine its efficacy when compared to pain control with intravenous morphine and oral oxycodone combined with acetaminophen. In addition, the study will evaluate the differences and similarities in the Hispanic population that could predict protocol efficacy.

NCT ID: NCT05375305 Completed - Pain Clinical Trials

A Study of SHR8554 Injection for the Treatment of Pain After Orthopedic Surgery

Start date: May 11, 2022
Phase: Phase 2/Phase 3
Study type: Interventional

The primary objective is to evaluate the analgesic efficacy of IV SHR8554 compared with morphine and placebo in patients with acute postoperative pain following orthopedic surgery.

NCT ID: NCT05373641 Completed - Pain Clinical Trials

Effect of Repeated Feedback to Registered Nurses Pain Nursing Documentation

Start date: March 4, 2022
Phase: N/A
Study type: Interventional

The aim of the study is to find out how pain nursing documentation audit and educational feedback effect to RN's pain nursing documentation, the average level of pain nursing documentation knowledge of unit RN's, patient satisfaction of pain management and number of pain nursing incident reports. In addition, how background variables are related to the pain nursing documentation. Research hypothesis: Pain nursing documentation audit and educational feedback increased RNs' pain nursing documentation and knowledge, patient satisfaction to pain management and effect to number of pain nursing incident reports.

NCT ID: NCT05366556 Completed - Pain Clinical Trials

The Effect of Virtual Reality on Pain and Anxiety During Blood Collection in Adults

Start date: March 10, 2022
Phase: N/A
Study type: Interventional

In hospitals, venous blood sampling as the first step in diagnosis and planning of medical treatment is among the most basic and common procedures all over the world. Before the diagnosis and treatment of acute or chronic health problems, venous blood is requested from the doctors and the blood sample is collected by the nurses. Patients experience anxiety for reasons such as the fear of experiencing pain during the blood donation process, fear of seeing blood, and fear that blood-borne diseases will pass. Studies in the literature have generally evaluated the effects on pain and fear by using virtual reality with different techniques in pediatric patients during blood collection, and the relevant research has been reached in adult patients. The aim of this research is to determine the effect of virtual reality on pain and anxiety during blood collection of patients who applied to the blood collection unit of a university hospital.