Clinical Trials Logo

Pain, Postoperative clinical trials

View clinical trials related to Pain, Postoperative.

Filter by:

NCT ID: NCT06082232 Not yet recruiting - Postoperative Pain Clinical Trials

Adjuvants With Intrathecal Bupivacaine for Postoperative Analgesia

Start date: November 1, 2023
Phase: Phase 4
Study type: Interventional

The aim of this study is to compare the postoperative analgesic effect of intrathecal dexmedetomidine combined with bupivacaine and midazolam combined with bupivacaine in high tibial osteotomy.

NCT ID: NCT06081335 Completed - Pain, Postoperative Clinical Trials

Can Instrumentation Kinematics Affect Post Operative Pain and Substance P Levels? A Randomized Controlled Trial

Start date: March 15, 2023
Phase: N/A
Study type: Interventional

The aim of this study was to evaluate the effect of continuous rotation and reciprocation kinematics on post operative pain and difference in substance P levels in patients with irreversible pulpitis with symptomatic apical periodontitis. Twenty patients were randomly distributed into two groups; Continuous Rotation group(n=10): received mechanical preparation using EdgeEndo x7 rotary system (Albuquerque, New Mexico, USA), while Reciprocation group(n=10): received mechanical preparation using EdgeOne Fire reciprocating system (Albuquerque, New Mexico, USA). Apical fluid(AF) samples were collected, and substance P (SP) levels were measured using radioimmunoassay and postoperative pain was measured using Numerical Rating Scale (NRS) preoperatively, at 6h, 12h, 24h, 48h and 72h.

NCT ID: NCT06079749 Completed - Clinical trials for Bilateral Total Knee Chronic Pain Following Arthroplasty

Risk of Chronic Post-surgical Pain After TKA

Start date: October 12, 2012
Phase:
Study type: Observational

Chronic post-surgical pain (CPSP) is a common surgical complication. The role of timing in the development of CPSP after bilateral total knee arthroplasty (BTKA) is not well studied. We aimed to compare the occurrence of CPSP in patients who underwent simultaneous or staged BTKA without discharge between procedures.

NCT ID: NCT06079047 Recruiting - Post Operative Pain Clinical Trials

Perineural Dexamethasone in the Adductor Canal Block

Start date: December 15, 2023
Phase: N/A
Study type: Interventional

Postoperative pain management in total knee arthroplasty (TKA) surgery is a real challenge for the anesthesiologist. Effective pain control must be provided while preserving the mobility to ensure early rehabilitation. The adductor canal block is an effective way to induce sensory block without motor block. However, the major disadvantage of this block is the duration of sensory block which may be insufficient for postoperative pain management in TKA surgery. Many studies have focused on finding molecules that can prolong sensory block without the need for a perineural catheter and dexamethasone is among the most studied molecules(1, 2). Hence, our study aims to evaluate the added value of perineural dexamethasone in the adductor canal block in TKA surgery. [

NCT ID: NCT06077422 Recruiting - Pain, Postoperative Clinical Trials

Exparel vs. Marcaine ESP Block for Post-cardiac Surgical Pain

Start date: January 11, 2024
Phase: Phase 2/Phase 3
Study type: Interventional

The goal of this pilot study is to describe and compare Ultrasound-Guided Erector Spinae Plane (ESP) Blocks using Exparel® (bupivacaine liposome injectable suspension) to Marcaine® (bupivacaine hydrochloride) for pain management and outcomes after cardiac surgeries.

NCT ID: NCT06077214 Recruiting - Clinical trials for Bariatric Surgery Candidate

Liposomal Bupivacaine for Post-operative Pain Control in Adolescent Bariatric Patients

Start date: January 31, 2023
Phase: Phase 1
Study type: Interventional

Liposomal bupivacaine (trade name Exparel) is a local analgesic that is designed to produce more long-term pain control. Bupivacaine, a widely used local analgesic, is stored within liposomes, which break down in soft tissue over time. Typical length of therapeutic effect for standard bupivacaine is up to 6 hours. The liposomal formulation of bupivacaine, however, has a length of therapeutic effect of up to 72 hours. Typical post-operative incisional pain is known to last for several days in most cases and is thought to peak between 1-2 days after surgery. Therefore, the benefit of most short-acting local analgesics does not overlap with the period of most need.

NCT ID: NCT06076707 Not yet recruiting - Pain, Postoperative Clinical Trials

Comparing Analgesic Effects of Wound Infiltration Using Bupivacaine, Tramadol, and Tramadol Plus Bupivacaine

Start date: November 30, 2023
Phase: Phase 4
Study type: Interventional

The goal of this study's clinical trial is to compare in post-operative analgesic effectiveness of wound infiltration using bupivacaine, tramadol, and tramadol plus bupivacaine in patients undergoing elective cesarean section under spinal anesthesia. The main question the study aimed to answer is "which approach is best among the 3" all participants need to respond to the pain severity for the data collectors and they will receive treatments accordingly There will be 3 groups in the study - group T: for tramadol - group B: for bupivacaine - group TB : tramadol + bupivacaine

NCT ID: NCT06075550 Completed - Clinical trials for Effect of Material and Technique

Assessment of Postoperative Pain of Two Bioceramic Root Canal Sealers With Obturation Techniques

Start date: June 2, 2021
Phase: N/A
Study type: Interventional

60 patients were divided into 2 groups, 30 patient in each group Group I: Obturation with TotalFill BC Sealer using the single cone technique Group II: Obturation with TotalFill BC Sealer HiFlow using the warm vertical compaction technique. Every participant will be given a Visual Analog Scale (VAS) to record the intensity of postoperative pain at 6 hr, 24 hr, 48 hr, 72 hr, and 1week after treatment. The patients will return their Visual Analog Scale (VAS) after 1 week and the recorded pain data will be collected and statistically analyzed regarding each group.

NCT ID: NCT06075498 Completed - Prostate Cancer Clinical Trials

Comparison of Analgesia Efficacy of Transversus Abdominis Plane Block and Posterior Approach Quadratus Lumborum Block

Start date: February 5, 2022
Phase: N/A
Study type: Interventional

Prostate cancer is the second most common cancer and the fifth in cancer-related deaths. Open radical retropubic prostatectomy is the most common surgical treatment for localized prostate cancer. Open radical retropubic prostatectomy is associated with moderate pain. Severe pain in the postoperative period affects the length of hospital stay and morbidity. Multimodal analgesia applications for the management of postoperative pain are the main component of post-surgical recovery. Different analgesia modalities, including systemic opioid use and neuraxial analgesia, have been used for pain control after retropubic radical prostatectomy. Side effects of systemic and intrathecal opioids limit the potential benefits of these agents. Transversus abdominis plane block and quadratus lumborum block are blocks that can be used for postoperative analgesia in the abdominal and pelvic regions. There is no study in the literature comparing the efficacy of these two blocks for postoperative analgesia in open radical retropubic prostatectomy and their effects on narcotic consumption.

NCT ID: NCT06073197 Completed - Anesthesia Clinical Trials

Comparison of Erector Spinae Block and Combined Deep and Superficial Serratus Anterior Plane Block

Start date: July 2, 2020
Phase: N/A
Study type: Interventional

Objective: The authors hypothesized that combined deep and superficial serratus anterior plane block (SAPB) is as effective as erector spinae plane block (ESPB) for intraoperative and postoperative analgesia for video-assisted thoracoscopic surgery. Design: A prospective randomized controlled study. Participants: Adult patients undergoing elective video-assisted thoracoscopic surgery. Interventions: Preoperative SAPB or ESPB implementation.