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Pain, Postoperative clinical trials

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NCT ID: NCT04774965 Not yet recruiting - Surgery Clinical Trials

The Effects of SlumberCurve™ Following Rotator Cuff Surgery: A Randomized Control Trial

Start date: June 30, 2024
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate the effects of a novel sleep aid known as SlumberCurve™, which serves as an adjustable form of a wedge pillow, on sleep quality and pain management following rotator cuff repair. The researchers hypothesize that SlumberCurve™ will significantly improve sleep quality and reduce night-time pain.

NCT ID: NCT04771689 Not yet recruiting - Post-operative Pain Clinical Trials

Buprenorphine/Naloxone Micro-Dosing for Postoperative Pain Management in Opioid-Tolerant Patients

Start date: July 1, 2022
Phase: Phase 4
Study type: Interventional

A randomized clinical study evaluating the effect of buprenorphine/naloxone (bup/nx) sublingual film on postoperative pain management in opioid-tolerant patients.

NCT ID: NCT04768764 Not yet recruiting - Pain, Postoperative Clinical Trials

Comparison Of Femoral Block And Middle Adductor Canal Block In Patients With Knee Arthroplasty

Start date: April 16, 2021
Phase: Phase 4
Study type: Interventional

Femoral and adductor nerve blocks with ultrasonography(USG) guidance are used effectively and efficiently in post-operative pain management in lower extremity surgical procedures. However, the superiority of these two blocks to each other is still controversial. In this prospective, randomized, double-blind study, patients who underwent elective unilateral knee arthroplasty under spinal anesthesia, will be performed postoperative femoral block or middle adductor canal block with the guidance of USG.Patients who underwent spinal anesthesia and needed sedoanalgesia and who had to switch to general anesthesia will be excluded from the study. The patients will be divided into two groups by simple randomization. Since a total of 52 patients should be included in the study as a result of the power analysis (G-power 3.1); It is planned to take approximately 26 patients for each group.The anesthesiologist, who follows the pain control and mobilization after the block, will not know which study group the patient is in. The blocks will be performed behind the cover while the patient is under spinal anesthesia (Thus, the point of application of the block will not be noticed). In this way, the patient and the anesthesiologist who follows the parameters after the block will be blind to patient's arm. In the first group, 0.25% 20 ml of local anesthetic and middle adductor canal block, in the second group 0.25% 20 ml of local anesthetic and femoral nerve block will be applied We will compare these two blocks in terms of early mobilization, postoperative pain control, motor, and sensory block.

NCT ID: NCT04757480 Not yet recruiting - Postoperative Pain Clinical Trials

Thoracolumbar Interfascial Plane Block Versus Bilateral Erector Spinae Plane Block In Lumbar Laminectomy

Start date: March 1, 2021
Phase: N/A
Study type: Interventional

The aim of this prospective randomized trial is to compare the efficacy ultrasound guided thoracolumbar interfascial plane block versus bilateral ultrasound guided erector spinae plane block for post-operative pain management after lumbar laminectomy

NCT ID: NCT04749095 Not yet recruiting - Pain, Postoperative Clinical Trials

Erector Spinae Plane Block Analgesia for Lumbar Spine Fusion Surgery

Start date: May 2021
Phase: N/A
Study type: Interventional

The purpose of this study was to investigate the effect of a bilateral ultrasound guided erector spinae plane block on the pain scores and opoid utiliziation in fusion surgery of the lumbar spine.

NCT ID: NCT04747171 Not yet recruiting - Pain, Postoperative Clinical Trials

Intrathecal Additives for Spinal Anaesthesia in Elective Caesarean Sections

Start date: April 2021
Phase: N/A
Study type: Interventional

we designed this randomized, single -blind, prospective clinical study to test postoperative analgesia of three intrathecal additives in elective caesarean sections which are magnesium, dexamethasone and dexmedetomidine.

NCT ID: NCT04742790 Not yet recruiting - Post-operative Pain Clinical Trials

QSPainRelief-patientCNS : Clinical Biomarkers of Nociception, Sedation and Cognition

Start date: March 15, 2021
Phase: N/A
Study type: Interventional

QSPainRelief-patientCNS is a monocentric prospective longitudinal study conducted in patients suffering from disabling post-surgical pain for which the treating physician is about to prescribe a given drug combination for the treatment of their pain with the aim of identifying measures of drug-induced effects on CNS activity that could be used as biomarkers of real-life clinical outcome, both in terms of desired treatment effects (treatment-induced pain relief) but also in terms of undesired treatment effects (treatment-induced sedation and treatment-induced cognitive dysfunction).

NCT ID: NCT04739787 Not yet recruiting - Postoperative Pain Clinical Trials

The Effects of Preoperative Physical Activities on Surgeries

Start date: December 2021
Phase:
Study type: Observational

Recommendation is strong on physical activity (PA) in the prehabilitation of Enhanced Recovery After Surgery (ERAS) for various types of surgeries. The evidence is however weak regarding ERAS protocols. Many studies have showed that physical exercise and PA have hypoalgesic effects on healthy individuals and they have better pain tolerance too. Here the investigators study changes in postoperative pain and postoperative nausea and vomiting for various types of surgical patients after performing preoperative PA at moderate or vigorous intensity Vs non-preoperative PA patients.

NCT ID: NCT04738500 Not yet recruiting - Postoperative Pain Clinical Trials

Postoperative Analgesic Efficacy of Pericapsular Nerve Group Block (PENG) Block for Knee Arthroscopy

Start date: April 15, 2021
Phase: N/A
Study type: Interventional

Pericapsular nerve group block (PENG) has been deemed as a safe and effective regional technique for postoperative pain after knee arthroscopy.

NCT ID: NCT04733326 Not yet recruiting - Post-operative Pain Clinical Trials

Evaluation of Post-operative Pain and Expression of IL-8 Using Ketolac or Cryoirrigation as a Final Flush in Single Visit Endodontic Treatment in Teeth With Symptomatic Irreversible Pulpitis and Apical Periodontitis.Randomized Clinical Trial.

Start date: April 1, 2021
Phase: Phase 1
Study type: Interventional

To compare the effect of cryotherapy versus ketorolac tromethamine irrigating solutions used as a final flush in single visit endodontic treatment in mandibular molars, with symptomatic irreversible pulpitis and apical periodontitis on the: - Intensity of post-operative pain in patients with symptomatic irreversible pulpitis - Reduction of expression of Interleukin-8 (IL-8) post-instrumentation using ELISA - The analgesic intake following endodontic treatment for post-operative pain relief.