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Pain, Postoperative clinical trials

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NCT ID: NCT00766506 Terminated - Pain, Postoperative Clinical Trials

An Efficacy and Safety Study to Compare Fentanyl Ionsys and Routine Care With Intravenous (IV) Morphine Patient-controlled Analgesia (PCA) in Participants Who Have Undergone Elective Major Abdominal or Orthopedic Surgery

Start date: May 2008
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate the mobilization characteristics, clinical use, safety and Ease of Care (EOC) of a fentanyl Iontophoretic Transdermal Patient Controlled Analgesia (PCA) system (Ionsys) and morphine intravenous (IV) PCA for management of moderate (medium level of seriousness) to severe (very serious) acute (a quick and severe) pain in participants who have undergone elective major abdominal or orthopedic (pertaining to the bones) surgery.

NCT ID: NCT00763685 Terminated - Pain Clinical Trials

Study to Evaluate the Efficacy of Pre-operative Administration of Etoricoxib 120 mg, Etoricoxib 120 mg and Paracetamol 1 g Combination or Placebo in the Treatment of Postoperative Pain in Patients Undergoing Gynaecologic Laparoscopic Surgery

Start date: June 2010
Phase: Phase 4
Study type: Interventional

Primary Hypothesis: 1. The analgesic effect of etoricoxib 120 mg administered 1 hour preoperatively is greater than that of placebo in the treatment of postoperative pain.

NCT ID: NCT00735124 Terminated - Pain Clinical Trials

Post-Operative Pain Scores and Analgesic Requirements After Elective Inguinal Herniorrhaphy

Start date: November 6, 2008
Phase: Phase 2/Phase 3
Study type: Interventional

The study will investigate the effects of single dose pre-operative oral dose of gabapentin (1200) on post -operative pain scores and oral analgesic requirements.

NCT ID: NCT00720343 Terminated - Postoperative Pain Clinical Trials

Effect of Oral Choline Supplementation on Postoperative Pain

Start date: February 2009
Phase: Phase 4
Study type: Interventional

This research will test whether consuming additional choline before gynecological surgery decreases postoperative pain.

NCT ID: NCT00712517 Terminated - Postoperative Pain Clinical Trials

Propofol Versus Volatile Anesthesia in Post Operative Pain Management

Start date: September 2010
Phase: N/A
Study type: Interventional

The study will test the hypothesis that patients anesthetized with propofol suffer less postoperative pain than those anesthetized with sevoflurane.

NCT ID: NCT00681174 Terminated - Pain, Postoperative Clinical Trials

Controlled-Release Oxycodone For Postoperative Analgesia After Video-Assisted Thoracic Surgery

Start date: July 2008
Phase: Phase 4
Study type: Interventional

The main hypothesis of this study is that preoperative administration of controlled-release (CR) oxycodone may reduce acute postoperative pain and improve time to discharge from the post-anesthesia care unit in patients undergoing video-assisted thoracoscopy for spontaneous pneumothorax. The study drug will be compared with intravenous morphine administered 30 minutes before the end of anesthesia.

NCT ID: NCT00661466 Terminated - Pain, Postoperative Clinical Trials

Efficacy and Safety of A Collagen Bupivacaine Implant in Patients After Gastrointestinal Surgery

Start date: July 24, 2008
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine whether the CollaRx Bupivacaine Implant (bupivacaine sponge) is safe and effective in reducing the amount of narcotic pain medication needed to control pain during the first 24 hours after gastrointestinal (GI) surgery.

NCT ID: NCT00638404 Terminated - Pain Clinical Trials

Severity Postoperative Pain Prediction

Start date: August 2007
Phase:
Study type: Observational

A simple preoperative evaluation assessing level of anxiety, anticipated pain, and intensity rating of audio tone will predict the severity of postoperative pain after surgery.

NCT ID: NCT00616824 Terminated - Postoperative Pain Clinical Trials

The Use of an Acellular Dermal Matrix in a Two-Staged Breast Reconstruction

Start date: September 2007
Phase: Phase 4
Study type: Interventional

This study intends to compare postoperative outcomes of a tissue expander placement following a mastectomy with two different operative techniques. This study will be randomized and double blinded comparing the traditional placement of the tissue expander under an inferolateral serratus muscle flap to a new technique which uses an acellular dermal matrix as an inferolateral sling, instead of the muscle flap. The study we are proposing will evaluate the question of whether there is a difference between the traditional method of serratus flap and the new technique of using an acellular matrix with tissue expander placement. This will be a double blinded randomized study of thirty women in each group comparing outcomes which will include postoperative pain, complications (wound infection, hematoma, capsular contracture, etc), and patient satisfaction with the procedure.

NCT ID: NCT00573664 Terminated - Pain Clinical Trials

The Effectiveness and Safety of Gabapentin for Post-operative Pain After Cesarean Section

Start date: November 2007
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether a single dose of gabapentin, given before cesarean section, will reduce pain in the initial 24 hours after surgery. Gabapentin has been very effective at treating pain after knee and hip operations, hysterectomies, and many other types of surgeries. We believe that it may be effective for treating pain after cesarean sections, but it has never been studied for this purpose.