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Pain, Postoperative clinical trials

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NCT ID: NCT05901389 Not yet recruiting - Pain, Postoperative Clinical Trials

Continuous Lidocaine Infusion Via Closed Chest Drainage Tube for Pain Control After Thoracoscopic Partial Lung Resection

Start date: June 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to learn about the effects on postoperative analgesia of continuous lidocaine infusion via closed chest drainage tube for patients undergoing thoracoscopic partial lung resection. The main questions it aims to answer are: - To explore whether continuous lidocaine pumping via closed chest drainage tube has good analgesic and anti-inflammatory effects for patients undergoing partial thoracoscopic pneumonectomy. - Whether the multimodal analgesia combined with continuous lidocaine pump can reduce the postoperative application of opioids, reduce the occurrence of postoperative complications, and promote the recovery of postoperative lung function and accelerate recovery. For participants who undergoing the thoracoscopic partial lung resection with postoperative indwelling drainage tube, the epidural tube fixed in the drainage tube is connected to the completed infusion pump (marking the chest drain for analgesia). The comparison group only accept the intravenous analgesia after surgery.

NCT ID: NCT05900791 Not yet recruiting - Opioid Use Clinical Trials

Persistent Pain After Knee Replacement

Start date: November 1, 2023
Phase:
Study type: Observational

This study is a nationwide cross-sectional survey on pain and satisfaction after knee arthroplasty (KA). Please find the full protocol uploaded at ClinicalTrials.gov The goal of this observational study is to study pain and satisfaction in patients operated with knee arthroplasty. The main question it aims to answer are: - What is the incidence of persistent postsurgical pain in unselected knee arthroplasty patients - What is the level of satisfaction in unselected knee arthroplasty patients? Participants will be asked to answer a 22-item questionnaire.

NCT ID: NCT05897450 Not yet recruiting - Pain, Postoperative Clinical Trials

The Effects of TAP Block on Thiol/Disulfide Homeostasis and Pain in Laparoscopic Gynecological Surgery

Start date: July 1, 2023
Phase:
Study type: Observational

In the study, it was aimed to compare patients who underwent laparoscopic gynecological surgery with and without TAP block in terms of postoperative pain levels and Thiol/Disulfide homeostasis. In addition, the relationship between postoperative pain levels and Thiol/Disulfide homeostasis will be investigated.

NCT ID: NCT05884268 Not yet recruiting - Clinical trials for Laparoscopic Cholecystectomy

Venlafaxine for Postoperative Pain of Laparoscopic Cholecystectomy

Start date: May 30, 2023
Phase: Phase 1/Phase 2
Study type: Interventional

Recent studies on the impact of perioperative venlafaxine for treatment of acute postoperative pain have yielded positive outcomes . The aim of the present study is to investigate the role of perioperative venlafaxine on the management of postoperative pain in patients undergoing LC.

NCT ID: NCT05868330 Not yet recruiting - Anesthesia Clinical Trials

Comparison of Interscalene Catheter to Single Injection Interscalene Blocks for Total Shoulder Arthroplasties

Start date: May 2024
Phase: N/A
Study type: Interventional

Comparison of post-operative pain after total shoulder surgery. The Principle Investigator will be comparing Exparel single shot block to Interscalene catheter

NCT ID: NCT05865366 Not yet recruiting - Clinical trials for Acute Postoperative Pain

Pain Trajectories and Predictors After Noncardiac Surgery in Elderly Patients

Start date: June 1, 2023
Phase:
Study type: Observational

This study will use group-based trajectory modeling to identify the different postoperative pain trajectory groups that exist in a mixed surgical population (non-cardiac surgery) of elderly patients during the first seven days after surgery. The aim of this study is to explore the diversity in the development of postoperative pain among elderly patients and to identify the risk factors for acute pain trajectory after surgery by investigating demographic, psychological, and clinical variables. The predictive effect of different trajectories of early postoperative acute pain on postoperative chronic pain will also be explored.

NCT ID: NCT05863624 Not yet recruiting - Post Operative Pain Clinical Trials

Open and Endoscopic Technique in Female Inguinal Hernia Repair. FemaleHernia

Start date: September 1, 2024
Phase: N/A
Study type: Interventional

This randomized study compares open inguinal hernia repair (Lichtenstein hernioplasty) to endoscopic repair (TEP) in terms of chronic pain and recurrences in one and five years after operation.

NCT ID: NCT05860686 Not yet recruiting - Third Molar Clinical Trials

Does Post-operative Rinsing With a Monoject Syringe Result in as Much Post-operative Pain After Surgical Removal of Lower Impact Third Molars as no Post-operative Rinsing: a Randomized Controlled Equivalence Trial

RITOR
Start date: June 1, 2023
Phase: N/A
Study type: Interventional

Many authors have advocated different methods of treating alveolar osteitis. Despite many years of research, however, little progress has been made and so a study with large enough sample and standard outcome measures is warranted. Goal of this study is assess the effect of postoperative use of a monoject syringe on postoperative complaints after surgical removal of a lower third molar.

NCT ID: NCT05854914 Not yet recruiting - Clinical trials for Appendicitis With Peritonitis

Benefit of Hypnosis on Smartphone for Acute Post-operative Pain (HYPNO-APP)

Start date: May 2024
Phase: N/A
Study type: Interventional

Appendicitis is a common pathology and the one of the most common surgical procedures performed in France. Young subjects are the most frequent patients with appendicitis. Appendicular peritonitis increases post-operative pain, morbidity, and the average length of hospital stay compared to uncomplicated appendicitis. Pain alters perioeprative rehabilitation of patients. Surgery, performed urgently, generates more anxiety and pain than scheduled surgery. But, intensity of chronic postoperative pain is in correlation to intensity of acute postoperative pain. In addition, admission of emergency cases is more axiety-inducing, due to wait times, packed emergency room, worklaod of medical staff. Sex and age also modify perception of postoperative pain. Adults under 50 feel more pain than older patients for similar procedures. Medication for pain is required in perioperative period et is administered according protocol of each medical center ; these protocols include analgesics, opioids or not, benzodiazepine... However, opioids analgesic (example: morphine) can induce side effect, such as confusional syndrome, cardio-pulmonary manifestations, ileus, nausea and vomiting... Non-pharmacological approaches have been also proposed to reduce anxiety and pain. Hypnosis is frequently used but not always adapted to the emergency: need for qualified and available staff, environment not conducive to hypnotic induction... Hypnosis is a modified state of consciousness ; it is neither a state of vigilance nor a state of sleep. Several types of hypnosis can be distinguished according to the medical application, such as hypnoanalgesia or hypnosedation. Using hypnosedation during surgical or invasive procedure can reduce the use of painkillers and sedatives. Interest of hypnosis has been observed for extraction of wisdow teeth, delivery... Young patients are very comfortable with the use of their smartphone which is often the first object recovered when they return from the operating room. Many hypnosis videos are available free of charge on Internet, and some of which are produced by specialized practitioners and university teachers. A recent study has shown that among young people, addiction to smartphone is a predisposition to hypnosis. However, the use of hypnosis videos on smartphone has never been studied for the control of postoperative pain.

NCT ID: NCT05843344 Not yet recruiting - Pain, Postoperative Clinical Trials

Dexmedetomidine and Morphine as Adjuvants to US Guided Erector Spinae Plane Blocks in Elective Thoracic Surgeries

Start date: May 1, 2023
Phase: N/A
Study type: Interventional

The aim of this study will be to compare the effects of morphine versus dexmedetomidine when used as adjuvants to local anesthetic (Ropivacaine) in Erector Spinae Plane Block under ultrasound guidance. A group without an adjuvant will also be compared to the groups.