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Overweight clinical trials

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NCT ID: NCT05969639 Recruiting - Obesity Clinical Trials

Improving Dietary Habit and Weight Loss in Young Adults With Overweight and Obesity: The Healthy Eating for Young Adults (HEYA) Study

Start date: July 25, 2023
Phase: N/A
Study type: Interventional

This study aims to examining the effectiveness of a psychoeducational program (Healthy Eating in Young Adults; HEYA) on improving the dietary habits and body composition (e.g. weight and percentage fat mass) in young adults in Singapore.

NCT ID: NCT05958368 Recruiting - Clinical trials for Diabetes Mellitus, Type 2

Assessing the Value of Avocados on Glycemic Control in Type 2 Diabetes

AVOCADO-T2D
Start date: October 10, 2023
Phase: N/A
Study type: Interventional

The objective of this study is to assess the effects of Hass Avocados on glycemic control. The investigators hypothesize that Hass Avocado consumption will reduce fasting blood sugar compared to an isocaloric amount of other fruit during controlled feeding.

NCT ID: NCT05949879 Recruiting - Clinical trials for Overweight and Obesity

Dose Response Effects of Pecan Consumption

Start date: August 1, 2023
Phase: N/A
Study type: Interventional

The bioactive compounds contained in tree nuts have been shown to beneficially affect cardiometabolic health outcomes. Pecans contain more total phenols, sterols, and flavonoids than any other tree nut. They also are a rich source of polyunsaturated fatty acids (PUFAs), fiber, vitamin A, vitamin E, folic acid, calcium, magnesium, phosphorus, potassium, and zinc. These bioactive components in pecans are likely the reason for the previously documented improvements in cardiometabolic health. The specific aims of this study are to: - Examine the effect of pecan consumption at doses of 6%, 13%, and 20% of total energy needs on fasting and postprandial blood lipids. - Examine the effect of pecan consumption at doses of 6%, 13%, and 20% of total energy needs on plasma markers associated with overall health. - Examine the effect of pecan consumption at doses of 6%, 13%, and 20% of total energy needs on subjective and physiologic postprandial measures of hunger and satiety. Participants will be asked to: - Consume pecans daily for 28 days or maintain their current habitual diet. - Attend three short weekly visits for fasting blood craws, body measurements, and collect their next week's supply of study materials. - Attend two longer (5 h) testing visits which include consuming a standard breakfast meal and having their blood drawn periodically before and after breakfast. Researchers will compare pecan LOW, pecan MID, pecan HIGH, and the Control group to examine the physiologic effects of incorporating various dosages of pecans into one's diet.

NCT ID: NCT05949710 Recruiting - Obesity Clinical Trials

Explore the Relationship Between Heart Rate Variability, Body Mass Index, Inflammation, and Insulin Resistance.

Start date: September 11, 2023
Phase: N/A
Study type: Interventional

The findings will serve as a reference for clinical professionals to promote exercise among the general population and will provide evidence of whether different exercise amounts are recommended for individuals with different BMIs for improving HRV.

NCT ID: NCT05943626 Recruiting - Type 2 Diabetes Clinical Trials

Circadian Intervention to Improve Cardiometabolic Health

TOCS
Start date: June 13, 2023
Phase: N/A
Study type: Interventional

The overall goal is to examine the efficacy of a circadian intervention in people with overweight and obesity and habitual short sleep duration (HSSD). Participants will undergo a randomized controlled trial, with circadian intervention and control (healthy lifestyle) groups. The circadian intervention is designed to reduce nighttime light exposure and after-dinner snack food intake. Alternatively, the control group will receive basic health information (e.g., physical activity, goal setting, and nutrition when eating out).

NCT ID: NCT05942287 Recruiting - Obesity Clinical Trials

The Effect of Obesity and Weight Loss in Heart Failure With Reduced Ejection Fraction.

SLEnDR
Start date: May 24, 2023
Phase: N/A
Study type: Interventional

This study looks at the effects of weight loss in people who have heart failure with reduced ejection fraction (HFpEF) and are overweight or obese. The main questions it aims to answer are whether weight loss in this group of people improves: - The heart's shape and how well it pumps blood - The person's quality of life and how much they can exercise Participants will attend 2 study visits, separated by 3-6 months. The intervention period takes place in between the 2 study visits. Each study visit may involve measurements including: Symptom and quality of life questionnaires Body measurements such as height and weight Blood tests Ultrasound scans of the heart (echocardiogram) Magnetic Resonance Imaging (MRI) scans of the heart 6 minute walk test Participants are randomly allocated (in other words, by lottery) to either 'diet' or 'control' groups. The control group will continue standard care. The diet group will be enrolled in a weight loss program supervised by the study team. Participants in the diet group will replace their usual meals with meal replacement products specifically designed to deliver a low calorie diet for weight loss. The products will consist of formula soups, shakes and porridges. This diet would last 8 weeks, followed by a guided period of food reintroduction and maintenance.

NCT ID: NCT05942144 Recruiting - Clinical trials for Overweight and Obesity

Exercise-snacks at Work: Impact on Cardiometabolic Parameters

Start date: May 16, 2023
Phase: N/A
Study type: Interventional

The main objective is to measure the effects of intense brief exercise program in the workplace of administrative staff on the cardio-metabolic health

NCT ID: NCT05941871 Recruiting - Clinical trials for Overweight and Obesity

Chronotype-adapted Diet and Weight Loss

CHRONODIET
Start date: March 6, 2023
Phase: N/A
Study type: Interventional

In humans, prolonged alterations in the circadian rhythm have been linked to cognitive impairments, premature ageing, and oncological and metabolic disorders such as diabetes and obesity. Obesity, in particular, is an ever-increasing condition with innumerable deleterious effects on human health. In recent years, studies have shown a relationship between a person's chronotype (morning or evening) and eating habits, as well as the importance of adapting these habits to physiological rhythms. Furthermore, it has been suggested that customising the caloric distribution of meals according to personal circadian rhythms may influence body weight and be one of the strategies to control overweight and obesity. In spite of the strong interest in this topic and the increasing number of observational studies conducted, there is currently a lack of intervention studies evaluating whether a low-calorie diet that takes into account the individual chronotype may be more effective than a standard low-calorie diet in the treatment of overweight and/or obesity.

NCT ID: NCT05941728 Recruiting - Clinical trials for Overweight and Obesity

Persea Americana for Total Health (PATH)-2

PATH-2
Start date: July 11, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to learn about the effects of avocado consumption on gastrointestinal health in adults with overweight and obesity. The main questions is aims to answer are: How does avocado consumption affect the gut microbiome? How does avocado consumption affect thinking? Are there connections between the microbiome and cognition? Participants will be asked to eat provided meals with and without avocados for three 4-week periods. At the end of each 4-week period, participants will be asked to provide stool samples and complete computer games that assess thinking and memory.

NCT ID: NCT05939544 Recruiting - Clinical trials for Cardiovascular Diseases

Impact of Milk Fat Globule Membrane Supplementation on Heart and Brain Health

Start date: July 10, 2023
Phase: N/A
Study type: Interventional

In a randomised, controlled cross-over manner, this trial aims to determine how short-term daily supplementation with a milk fat globule membrane-enriched ingredient impacts on cardiometabolic health and cognitive outcomes.