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Overweight clinical trials

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NCT ID: NCT03465800 Recruiting - Physical Activity Clinical Trials

Understanding Mechanisms of Exercise Behavior Change

Start date: February 26, 2018
Phase: N/A
Study type: Interventional

This research seeks to examine psychological factors that may impact relationship between incentives and health behavior engagement, specifically physical activity. Additionally, it will compare the impact of two different incentive schedules on behavior engagement, one providing immediate rewards (i.e. rewards received on a daily basis) and another providing delayed rewards (i.e. rewards received at the end of the study period), with an active self-monitoring intervention condition in which no rewards are offered. Study participants will provide reports of their physical activity each day for three weeks, and in the two incentive conditions, they will receive small monetary rewards for their physical activity. Following the three week reporting and reward period, participants will complete two additional assessments, measuring psychological constructs and behavior engagement following the cessation of rewards. The study will also examine how cognitive and anthropomorphic factors may contribute to intervention response and the effects on psychological constructs.

NCT ID: NCT03464500 Recruiting - Overweight Clinical Trials

AMAZ-02 Effect on Exercise ToLerance in Healthy, Overweight Middle Aged Subjects (ATLAS Trial)

Start date: March 6, 2018
Phase: N/A
Study type: Interventional

This is a Phase 2 randomized, double-blind, placebo-controlled study enrolling 90 healthy, overweight, middle aged subjects (30 placebo, 30 low dose and 30 high dose AMAZ-02 intervention), 40-65 years of age, who are otherwise healthy. AMAZ-02, a food derived ingredient, will be given as a daily oral dose for 4 months.

NCT ID: NCT03459703 Not yet recruiting - Obesity Clinical Trials

Effect of Time-Restricted Feeding on Fat Loss and Cardiometabolic Risk Factors in Overweight Adults

Start date: April 2018
Phase: N/A
Study type: Interventional

Time-restricted feeding (TRF) is a novel type of intermittent fasting that involves eating within a daily period of 10 hours or less, followed by fasting for at least 14 hours daily. Several studies in rodents report that TRF reduces body weight, improves blood sugar control, and reduces the risk of cardiovascular disease—even when food intake is matched to the control group or no weight loss occurs. Preliminary evidence suggests that TRF may also increase weight loss, fat loss, and reduce the risk of diabetes and cardiovascular disease in humans. This study will test whether TRF enhances fat loss and increases weight loss in adults with obesity, relative to conventional dieting alone. In addition, this study will determine whether TRF reduces risk factors for type 2 diabetes and cardiovascular disease and will measure the feasibility and acceptability of TRF.

NCT ID: NCT03458533 Recruiting - Metabolic Syndrome Clinical Trials

Changes in the Hypotalamic-pituitary Region of Patients With Metabolic Syndrome and Obesity

Start date: November 2016
Phase: N/A
Study type: Observational

This study aims to identify new morphological and quantitative magnetic imaging parameters of pituitary gland and sellar region in overweight and obese patient at baseline and after 3 years, dividing patients in 3 groups (weight loss through diet and lifestyle changes, weight loss through bariatric surgery, no weight loss)

NCT ID: NCT03454997 Not yet recruiting - Clinical trials for Overweight and Obesity

Adapting an Evidenced-based Weight Management Intervention and Testing Strategies to Increase Implementation in Community Mental Health Programs

Start date: March 2018
Phase: N/A
Study type: Interventional

This is a pilot randomized clinical trial testing an implementation intervention to support delivery of a behavioral weight loss program at community mental health programs.

NCT ID: NCT03448094 Recruiting - Clinical trials for Overweight and Obesity

The Effects of Resveratrol Supplementation on Cognition, Cerebral Blood Flow, Microbiota and Systemic Inflammation.

Start date: February 6, 2018
Phase: N/A
Study type: Interventional

Previous research shows that a diet high in fat has harmful effects on gut health. This increases the chance of developing obesity-related diseases (such as type 2 diabetes) and disrupts cognition and mood. Research has suggested that gut health can be improved by taking certain supplements, including resveratrol (a polyphenol found primarily in red grape skins). Resveratrol has also been shown to improve brain blood flow and possibly brain function - however, there is limited research studying this. This study will investigate the effects of 12 weeks daily consumption of resveratrol on cognitive function, cerebral blood flow, gut microbiota and systemic inflammation in overweight and obese healthy adults.

NCT ID: NCT03447600 Recruiting - Clinical trials for Overweight and Obesity

Diet-Induced Variability in Appetite (DIVA)

Start date: March 1, 2018
Phase: N/A
Study type: Interventional

The aim of this study is to test the hypothesis that dietary weight loss (WL) through alternate day fasting (ADF) will enhance appetite control, health markers and wellbeing following WL compared to standard daily calorie restriction (CR).

NCT ID: NCT03446729 Completed - Clinical trials for Overweight and Obesity

Enhancing Memory to Facilitate Weight Loss: Tracking, Recording and Coaching

Start date: January 2, 2014
Phase: N/A
Study type: Interventional

The objective of this application is to pilot test and evaluate the acceptability and efficacy of a program to facilitate weight loss by enhancing memory for a recently consumed meal.

NCT ID: NCT03444584 Not yet recruiting - Clinical trials for Type 2 Diabetes Mellitus

Study of MEDI0382 in Combination With Dapagliflozin and Metformin in Overweight/Obese Subject With Type 2 Diabetes

Start date: March 22, 2018
Phase: Phase 2
Study type: Interventional

A Phase 2 study Comparing the effects on glucose control of Medi0382 in combination with Dapagliflozin and Metformin compared to placebo in combination with Dapagliflozin and Metformin in overweight/obese patients with Type 2 Diabetes Mellitus, Approximately 46 subjects.

NCT ID: NCT03441308 Active, not recruiting - Clinical trials for Overweight and Obesity

"Dare to be Satisfied With Food" - a Group Treatment Method

Start date: September 16, 2015
Phase: N/A
Study type: Interventional

The concept "Dare to be satisfied with food" is an educational method of group treatment based on regular meals and food based on Nordic nutrition recommendations. The method has been developed by a district nurse at the city of Ljungby, Sweden and has shown permanent weight loss in a limited number of persons who tested the method. It is important to test the method scientifically and in the long term for possible implementation in routine activities in the healthcare sector. Adults with overweight and obesity (BMI 27-45) will be recruited to the study by announcing in newspapers in the counties of Kronoberg and Kalmar and then randomized to intervention group and control group, where the control group receives dietary advice according to the Swedish National Food Agency's guidelines for overweight and obesity (including brochures).