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Overweight clinical trials

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NCT ID: NCT03586843 Recruiting - Obesity Clinical Trials

A Study to Evaluate the Relative Bioavailability of JNJ-64565111 After Subcutaneous Administration at Different Injection Sites in Otherwise Healthy Overweight/Obese Adult Participants

Start date: June 29, 2018
Phase: Phase 1
Study type: Interventional

The purpose of this study is to compare the relative bioavailability of JNJ-64565111 between subcutaneous (SC) administrations in the upper arm versus the abdomen, and between SC administrations in the thigh versus the abdomen in otherwise healthy overweight/obese participants.

NCT ID: NCT03586765 Completed - Clinical trials for Relationship Between Menopause and Urinary Functional Disorders

Epidemiology of Urinary Functional Disorders in Women of 40 and More

Start date: November 13, 2017
Phase:
Study type: Observational

Assess prevalence of urinary functional disorders in women of 40 and more, visiting a general practitioner, occupational medicine or health examination center in Puy-de-Dôme. Study conducted for a month using a self-filled survey distributed by secretaries or nurses.

NCT ID: NCT03581630 Recruiting - Breast Cancer Clinical Trials

Effects of Mediterranean Diet and Naltrexone/Bupropion Treatment in Obese Breast Cancer Patients

Start date: June 1, 2017
Phase: N/A
Study type: Interventional

Obesity among breast cancer survivors is known to be associated with recurrence and other co-morbidities. However, there have been no studies on weight reduction program combining diet and anti-obesity drug for obese breast cancer survivors. The purpose of this randomized clinical trial is to examine the effects of Mediterranean Diet and naltrexone/bupropion treatment on inflammation and metabolic risk factors in overweight or obese breast cancer patients after breast cancer treatment.

NCT ID: NCT03576703 Completed - Inflammation Clinical Trials

Sugar-sweetened Beverages Influence Benefits of Exercise in Overweight Adults

Start date: October 24, 2014
Phase: N/A
Study type: Interventional

The objective of this study was to determine how metabolic and inflammatory effects of physical exercise in overweight individuals are altered when sugar-sweetened beverages (SSB) are consumed after physical exercise. A randomized, controlled crossover trial was performed in which participants performed exercise with and without the ingestions of SSB during exercise or a non-exercise control condition to evaluate metabolic and inflammatory responses one day after the exercise and or SSB treatment.

NCT ID: NCT03574597 Not yet recruiting - Obesity Clinical Trials

Semaglutide Effects on Heart Disease and Stroke in Patients With Overweight or Obesity

SELECT
Start date: October 24, 2018
Phase: Phase 3
Study type: Interventional

The researchers are doing the study to see if semaglutide may reduce the risk of having cardiovascular events in patients with overweight or obesity and with prior cardiovascular disease. The participant will either get semaglutide (active medicine) or placebo ("dummy" medicine). Which treatment the participants get is decided by chance. The participant's chance of getting semaglutide or placebo is the same. The participant will get the study medicine in a pen. The participants will need to use the pen to inject the study medicine in a skinfold once a week. The study will last for about 2.5 to 5 years. Participants will have up to 25 clinic visits with the study doctor.

NCT ID: NCT03574584 Recruiting - Clinical trials for Overweight or Obesity

A Research Study of NNC0165-1562 and Semaglutide in People Who Are Overweight or Obese

Start date: June 19, 2018
Phase: Phase 1
Study type: Interventional

The study is investigating new medicines for weight control in people with high body weight. The study looks at how the study medicines work in the body. Participants will get semaglutide and either NNC0165-1562 or "dummy" medicine -which treatment participants get is decided by chance. Participants will get 2 injections per week for 5 months. A study nurse at the clinic will inject the medicine with a thin needle in a skin fold in the stomach. The study will last for about 7 months. Participants will have 27 visits to the clinic.

NCT ID: NCT03574519 Completed - Physical Activity Clinical Trials

Project Step II: The Effects of Incentives and Feedback on Promoting Walking Within Overweight and Obese Adults

Start date: June 1, 2017
Phase: N/A
Study type: Interventional

This study will evaluate the main effects of daily vs. weekly feedback and contingent vs. non-contingent incentives for increasing walking behavior among overweight and obese adults.

NCT ID: NCT03574103 Not yet recruiting - Clinical trials for Overweight and Obesity

Chronic Effect of Fasting

Start date: July 2018
Phase: N/A
Study type: Interventional

The aim of the study is to determine if time-restricted feeding (TRF) is an effective dietary strategy to weight loss after 8 weeks intervention. TRF will be compared with an intervention without restriction in time for feeding. Both strategies will be with caloric restriction.

NCT ID: NCT03573856 Not yet recruiting - Overweight/Obesity Clinical Trials

Reducing Diabetes Risk Factors in American Indian Children: Tribal Turning Point

TTP
Start date: July 2018
Phase: N/A
Study type: Interventional

This study will evaluate a behavioral intervention designed to reduce risk factors for type 2 diabetes in American Indian youth aged 7-10 years.

NCT ID: NCT03573414 Not yet recruiting - Healthy Overweight Clinical Trials

Gut Microbial Metabolism of Polyphenols and Cardiovascular Health (Stratification Study)

Start date: June 2018
Phase: N/A
Study type: Interventional

There is increasing interest in the effects of various food derived polyphenols on cardiovascular health. Several studies have demonstrated improvements in vascular function after intake of polyphenol rich foods. The objective of this study is to investigate the association between polyphenol microbiota metabolism and cardiovascular health. The participants (n=250) with age range between 20 to 70 years old health overweight men and women. The participants will consume a polyphenol rich breakfast for three days (consisting on milled flaxseed, raspberry powder and soy milk). The participants will provide the investigators with urine and blood samples for polyphenol analysis. Cardiovascular measurements such as PWV, AIx, Blood Pressure and FMD will be performed at baseline and after 72h.