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Overweight clinical trials

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NCT ID: NCT03254576 Recruiting - Obesity Clinical Trials

Cue-Reward Learning and Weight Gain in Youth

Child Learn
Start date: December 2016
Phase: N/A
Study type: Observational

The objective of the study is to compare children at low risk for obesity (two healthy weight parents) to children at high risk for obesity (two overweight parents) in their response rate to food taste and in their rate of learning using fMRI.

NCT ID: NCT03254368 Not yet recruiting - Clinical trials for Type 2 Diabetes Mellitus

Study to Assess the Effects and Safety of ZGN-1061 in Overweight and Obese Participants With Type 2 Diabetes

Start date: August 2017
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of the study drug ZGN-1061 in participants with type 2 diabetes.

NCT ID: NCT03249324 Active, not recruiting - Obesity Clinical Trials

Preventing Obesity in Military Communities: Mother-Baby

Start date: November 2014
Phase: N/A
Study type: Interventional

Women with pre-pregnancy obesity, women who exceed recommended weight gain during pregnancy, and children who experience rapid and excess growth during the first year of life are all at risk for subsequent obesity. The purpose of this study is to examine creative cognitive strategies to promote healthy weight gain during pregnancy, creating a sound substrate of metabolic programming for the critical first six months of life. A trans-disciplinary approach utilizing a patient- and family-centered intervention and active patient engagement with counseling for positive gain will work with women to shape lifestyle during pregnancy and postpartum, and when feeding their infants in the first 6 months of life. It is hypothesized patient engagement with counseling for positive gains will successfully mitigate excess weight gain in both pregnancy and infancy compared to usual care. Moreover, data will be examined to assess whether psychological variables, work and school climate, and social support factors influence body weight gain trajectories and/or weight loss during and after pregnancy.

NCT ID: NCT03248804 Completed - Obesity Clinical Trials

Effect of Soy Protein and Colorado Diet on Weight Loss and Maintenance

Start date: March 10, 2015
Phase: N/A
Study type: Interventional

Dietary protein is a key element of most effective weight loss regimens. This study will investigate the effects of consuming soy protein on body composition and cardiometabolic health within the context of an effective weight loss and maintenance program called the Colorado Diet.

NCT ID: NCT03244800 Not yet recruiting - Clinical trials for Type 2 Diabetes Mellitus

A Study to Investigate Different Doses of 0382 in Overweight and Obese Subjects With Type 2 Diabetes Mellitus.

Start date: September 4, 2017
Phase: Phase 2
Study type: Interventional

A Phase 2 study with two cohorts of differing doses designed to evaluate the efficacy, safety and pharmacokinetics (PK) of MEDI0382 in patients with Type 2 Diabetes Mellitus. Approximately 63 subjects will be enrolled across two cohorts.

NCT ID: NCT03240978 Completed - PreDiabetes Clinical Trials

Exercise Intervention for the Prevention of Prediabetes in Overweight Chinese

Start date: September 2016
Phase: N/A
Study type: Interventional

Overweight/obese Chinese and prediabetes will be recruited and divided into three age-matched groups including high intensity exercise, moderate intensity exercise, and non-exercise groups. The exercise program will consist of three sessions per week over the course of 12 weeks, under the supervision of our in-house exercise specialists and physiologists. The effects of exercise on glucose and lipid profiles, insulin sensitivity and adiposity will be evaluated.

NCT ID: NCT03236285 Not yet recruiting - Obesity Clinical Trials

Microvascular and Metabolic Effects of High-intensity Interval Exercise Training

HIIT-FAST
Start date: October 2017
Phase: N/A
Study type: Interventional

The study investigates the effects of high intensity interval training (HIIT) versus continuous training (CT), combined or not with fasting, on capillary density, microvascular function, cardiometabolic risk markers, functional capacity, and quality of life, in overweight or obese sedentary women with cardiometabolic risk factors. The use of HIIT could promote greater improvements in these parameters than CT. Furthermore, the positive effects of exercise may increase when it is performed in the fasting state, compared to exercise performed in the fed state.

NCT ID: NCT03236259 Recruiting - Clinical trials for Cognitive Impairment

The Effect of Berry Extract Administration on Cognitive Health

Start date: February 21, 2017
Phase: Phase 2
Study type: Interventional

The purpose of this study is to investigate the effects of daily supplementation of Brainport for a period of 6 months on cognitive health.

NCT ID: NCT03236181 Recruiting - Obesity Clinical Trials

Chronic Effects of Fats on Satiety & Energy Needs

Start date: August 2017
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the effect of dietary fat on satiety (the experience of fullness between one meal and the next) and energy metabolism over an extended period of time (chronic effects). How dietary fat sources affect satiety, appetite and energy use is unclear. The investigators will use a controlled setting for the studies. They want to know if the source of dietary fat alters satiety, satiety hormones, and energy expenditure responses after consuming different diets.

NCT ID: NCT03235050 Recruiting - Clinical trials for Diabetes Mellitus, Type 2

A Study to Evaluate the Efficacy and Safety of MEDI0382 in the Treatment of Overweight and Obese Subjects With Type 2 Diabetes

Start date: August 2, 2017
Phase: Phase 2
Study type: Interventional

This study is designed to evaluate the dose range for MEDI0382 with respect to blood glucose control and weight loss effects, as well as to further explore the safety profile of MEDI0382.