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Obesity, Morbid clinical trials

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NCT ID: NCT06015620 Recruiting - Hypertension Clinical Trials

Comorbidities Resolution After MGB Surgery and Change in Body Composition

MOGAMBO
Start date: September 1, 2023
Phase:
Study type: Observational

This observational study aims to learn about the correlation between the improving comorbidities associated with obesity after MGB (Mini-Gastric Bypass) surgery and changes in body composition in morbidly obese patients. The main questions it aims to answer are: To study the correlation between the improving comorbidities associated with obesity after MGB(Mini-Gastric Bypass) surgery and changes in body composition. Other objectives are: - Changes in the parameters of the metabolic syndrome after surgery - Changes in the cardiovascular risk biomarkers after metabolic surgery - Emergence in complications arising out of surgery requiring any intervention or causing a prolonged hospital stay, or requiring additional outpatient visits. Type of Study: An observational study in which participants with morbid obesity will undergo mini-gastric bypass surgery as per routine protocol. No separate experimental interventions will be done in the study for the participants.

NCT ID: NCT06002906 Recruiting - Obesity, Morbid Clinical Trials

The Use of Indocyanine Green to Visualize Blood Flow to the Gastrojejunostomy During Bariatric Surgery.

Start date: January 25, 2023
Phase: Phase 4
Study type: Interventional

This is an interventional pilot study aimed to evaluate the use of NIF imaging as an intraoperative aid to assess the anastomotic blood flow to the gastric pouch and gastrojejunostomy during Roux-en-Y gastric bypass surgery and to determine its long-term impact on the rate of marginal ulceration, leaks and stricture.

NCT ID: NCT06000969 Recruiting - Obesity, Morbid Clinical Trials

Lung Recruitment Manoeuvre in Morbidly Obese Patients Underdoing Laparoscopic Bariatric Surgery

Start date: August 14, 2023
Phase: N/A
Study type: Interventional

Lung ultrasonography is an easy-to-use, portable, non-invasive, visual, and non-radiative technique that has been widely used in clinical monitoring and diagnosis. Many studies have demonstrated that pulmonary ultrasonography can evaluate the degree of aeration loss and diagnose atelectasis accurately by using a validated semiquantitative score in the perioperative period, and lung ultrasonic imaging can be conducive to confirming the effects of lung recruitment manoeuvres. This clinical trial suggested that the use of ultrasound-guided recruitment maneuver in morbidly obese patients scheduled for laparoscopic bariatric surgery can improve the lung aeration, decrease the incidence of basal lung atelectasis, decrease the incidence of intraoperative& postoperative oxygen desaturation, and reduce the incidence of post operative pulmonary complications. The aim of this prospective randomized clinical study is to compare the conventional recruitment manoeuvre and ultrasound-guided recruitment manoeuvre in morbidly obese patients scheduled for laparoscopic bariatric surgery.

NCT ID: NCT05993169 Terminated - Obesity, Morbid Clinical Trials

Body Composition Optimization Intervention RCT

Start date: September 15, 2023
Phase: N/A
Study type: Interventional

This study aims to identify if the addition of structured nutrition/weight loss counseling to patients at the bariatric clinic can increase the conversion from bariatric clinic to surgical candidacy from (the current) 11% to a goal of 20% by way of tracking their BIA measurements.

NCT ID: NCT05987787 Completed - Clinical trials for Bariatric Surgery Candidate

Suture Reinforcement to Reduce the Leak Rate After Sleeve Gastrectomy

Start date: January 1, 2022
Phase:
Study type: Observational

Staple line reinforcement (SLR) has been suggested as a mean of reducing the risk of sleeve leakage or bleeding. The aim of this study is to analyze if the suture reinforcement can be used to reduce the leakage rate after sleeve gastrectomy.

NCT ID: NCT05987631 Recruiting - Clinical trials for Bariatric Surgery Candidate

Predictors of Weight Loss and Metabolic Health After Bariatric Surgery

Start date: January 19, 2023
Phase:
Study type: Observational

In this prospective study the investigators aim to identify preoperative predictors of improvement of metabolic health and weight loss after bariatric surgery focusing on inflammation, insulin sensitivity (in a subgroup of patients), glucoregulatory determinants, psychological traits, feeding behavior characteristics and cardiorespiratory fitness

NCT ID: NCT05974995 Not yet recruiting - Endometrial Cancer Clinical Trials

Robotic-assisted Versus Conventional Laparoscopic Surgery in Obese Patients With Early Endometrial Cancer

RObese
Start date: September 1, 2023
Phase: N/A
Study type: Interventional

Data across literature suggest that robotic surgery may offer benefit specifically in patient with morbid obesity with endometrial cancer, but to date no randomized trials have been conducted to confirm these observations. This randomized controlled multicentric trial aims to evaluate the most appropriate minimally invasive surgical approach in morbidly obese (BMI >= 30) patients with endometrial carcinoma.

NCT ID: NCT05961345 Active, not recruiting - Obesity, Morbid Clinical Trials

The Effect of Early Mobilization on Pain Level After Laparoscopic Bariatric Surgery

Start date: August 1, 2022
Phase: N/A
Study type: Interventional

According to the definition of the WHO, obesity is the abnormal or excessive accumulation of fat in the body. Laparoscopic operations; It is a popular choice for bariatric surgery. A study is planned to determine postoperative early mobilization, postoperative pain and hospital stay in patients hospitalized in Bariatric Surgery post-operative clinics.

NCT ID: NCT05958615 Not yet recruiting - Obesity, Morbid Clinical Trials

Positive Psychology Intervention for Patients Post-bariatric Surgery and Their Partners

Start date: November 2023
Phase: N/A
Study type: Interventional

The goal of this waitlist-control design, pilot randomized controlled trial is to test feasibility, acceptability, and preliminary efficacy of a remotely-delivered dyadic positive psychology intervention for patients 2 years after bariatric surgery and their romantic partners (called ReConnect). The main question it aims to answer is whether the intervention results in improvements in depressive symptoms for patients and partners. The additional questions it aims to answer are whether the intervention results in improvements in resilience, relationship satisfaction, eating and physical activity behaviors, and weight maintenance for those in the intervention versus waitlist control condition. Participant couples randomly assigned to the intervention condition will engage in ReConnect for 8 weekly modules and associated positive psychology activities, some individually and some as a couple. Participant couples randomly assigned to the waitlist control condition will wait for 8 weeks to begin the 8 week intervention. All participants will fill out assessment measures at baseline, 8 weeks, and 16 weeks.

NCT ID: NCT05948852 Not yet recruiting - Obesity, Morbid Clinical Trials

Two Hypoabsorption Techniques for the Treatment of Type III Obesity (OASIS)

OASIS
Start date: July 2023
Phase: N/A
Study type: Interventional

This study aims to compare the percentage of total weight lost in long-term follow-up after two surgical interventions (SADIS and OAGB) in patients with morbid obesity BMI between 45-49.9.