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Nephrolithiasis clinical trials

View clinical trials related to Nephrolithiasis.

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NCT ID: NCT02818140 Completed - Kidney Stone Clinical Trials

Ultrasound-guided Transmuscular Quadratus Lumborum Block for Percutaneous Nephrolithotomy

Start date: July 2016
Phase: Phase 4
Study type: Interventional

Patients undergoing percutaneous nephrolithotomy (PNL) suffer from acute postoperative pain, despite a multimodal analgesic regime. We hypothesize that active (ropivacaine) transmuscular quadratus lumborum (TQL) block will significantly reduce postoperative opioid consumption and pain following PNL operation compared with placebo (saline) TQL block. The aim of this study is to investigate the effect of ultrasound-guided (USG) TQL block concurrent with a multimodal analgesic regime compared to the multimodal analgesic regime alone (and placebo TQL block) in a randomized and placebo controlled design.

NCT ID: NCT02786446 Completed - Renal Stone Clinical Trials

Comparison of Different Analgesia Drug Regimens for Pain Control During ESWL for Renal Stones

Start date: July 2015
Phase: N/A
Study type: Interventional

We want to compare the effect of lignocaine 2 % gel, Naproxen sodium and their combination on the pain control during extracorporial shock wave lithotripsy for renal stones.

NCT ID: NCT02739919 Completed - Urolithiasis Clinical Trials

Bacterial Analysis of Kidney Stones Removed by Percutaneous Nephrolithotomy

Start date: June 2016
Phase:
Study type: Observational

The aim of this research is to use a controlled laboratory setting to determine whether bacteria isolated from kidney stones of patients play a role in the formation of non-infectious kidney stones. It is well known that struvite stones are associated with active bacterial infection, however the role of bacteria in the formation of non-infection stones (like calcium oxalate) is not well characterized and there are theories that bacteria are involved in the making of these stones.

NCT ID: NCT02711670 Completed - Kidney Stones Clinical Trials

Night Time Use of Thiazide Diuretics for Improved Reduction in Stone Risk in Stone Formers With Elevated Urine Calcium

Start date: February 2014
Phase: N/A
Study type: Interventional

Thiazide diuretics will be more effective in lowering urine calcium excretion if taken at night as compared to the daytime. It will therefore be more effective in reducing kidney stone recurrence in nephrolithiasis patients with elevated urine calcium who are known to have increased risk of kidney stones at night time.

NCT ID: NCT02690662 Completed - Obesity Clinical Trials

Influence of Hypocaloric Diet on Urinary Lithogenic Factors of Obese Patients With Kidney Stones

Start date: February 2016
Phase: N/A
Study type: Interventional

The objective of this study is to evaluate the influence of low-calorie diet on serum and urinary metabolic parameters of obese adults with urinary calculi and lithogenic metabolic abnormalities.

NCT ID: NCT02658942 Completed - Renal Stones Clinical Trials

Flexible Ureteroscopy Versus ESWL in the Management of Lower Calyceal Stones

Start date: May 2010
Phase: N/A
Study type: Interventional

to assess safety, efficacy of Flexible ureteroscopy (FURS) holmium:YAG laser lithotripsy (LL) compared to extracorporeal shockwave lithotripsy (ESWL) in management of lower calyceal stones (LC) stones.

NCT ID: NCT02645058 Completed - Renal Stones Clinical Trials

RIRS Versus ESWL for the Treatment of Renal Stones

Start date: March 2, 2015
Phase: N/A
Study type: Interventional

To evaluate the effectiveness of RIRS (retrograde intrarenal surgery) and ESWL (extracorporeal shockwaves lithotripsy) in the treatment of renal stone ranging form 6 to 20 mm size.

NCT ID: NCT02635048 Completed - Kidney Calculi Clinical Trials

Mini-PCNL Versus Standard-PCNL For The Management of 20-40 mm Size Kidney Stones

Start date: January 1, 2016
Phase: N/A
Study type: Interventional

Percutaneous nephrolithotomy (PCNL) has been considered as the first-line choice for the management of >20mm kidney stones. The traditional nephrostomy tract of PNL was dilated to 24-30F, which is referred to as "Standard-PCNL". Standard PNL has an ideal stones free rate (SFR), however, at the cost of severe morbidity. To decrease the disadvantages related to standard PNL, "mini-perc" or "mini-PCNL", 20F or less, was first introduced to pediatric procedure in 1997, and subsequently implemented in adults with the expectation of similar SFR and low morbidity in the past twenty years. Although abundant efforts have been done, whether mini-perc outweigh standard-PNL for the treatment of >20mm calculis in terms of efficiency and safety remains controversial. To solve this problem, we performed this multicenter, parallel, open-label randomized controlled trial (RCT).

NCT ID: NCT02625051 Completed - Quality of Life Clinical Trials

Quality of Life in Kidney Stone Patients Undergoing Surgery

Start date: July 2016
Phase: N/A
Study type: Interventional

This is a prospective randomized study, comparing quality of life in renal stone patients undergoing surgical treatment with ureteroscopy (URS) versus percutaneous nephrolithotomy (PNL).

NCT ID: NCT02579161 Completed - Kidney Stones Clinical Trials

Trial of Randomized Antibiotic Administration in Percutaneous Nephrolithotomy

Start date: September 2014
Phase: Phase 3
Study type: Interventional

The Investigators objective is to compare the clinical efficacy of a single-day protocol with a short-course protocol for PCNL. The investigator hope is to reduce the use of possibly unnecessary prolonged antibiotic use, reduce hospital costs and prevent the further propagation of resistant microbes.