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Nephrolithiasis clinical trials

View clinical trials related to Nephrolithiasis.

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NCT ID: NCT03095885 Completed - Nephrolithiasis Clinical Trials

A Pilot Study of Oxalate Absorption in Secondary Hyperoxaluria

Start date: November 2016
Phase: N/A
Study type: Interventional

Identify individuals with greater absorption of oxalate based on increase in urinary oxalate excretion in response to a controlled oxalate-rich test meal.

NCT ID: NCT03087812 Completed - Kidney Stones Clinical Trials

Durability of Flexible Ureteroscopes and Causes of Infection During Flexible Ureterorenoscopy

Start date: December 2015
Phase:
Study type: Observational

This is an observational study in which data on consecutive patients who undergo ureterorenoscopy with the use of a flexible ureterorenoscope are collected. In total 20 new ureteroscopes are usedfrom Olympus andfrom Storz) to study the durability of the ureteroscopes and the possible microbiological load.

NCT ID: NCT03087149 Completed - Clinical trials for Vitamin D Deficiency

Monitored vs Standard Supplementation of Vitamin D in Preterm Infants

MOSVID
Start date: May 1, 2017
Phase: N/A
Study type: Interventional

The purpose of this study is to determine wheather the monitored vitamin D (vit D) therapy is safer and more effective than standard therapy in pretrem infants.

NCT ID: NCT03057431 Completed - Nephrolithiasis Clinical Trials

Hydrochlorothiazide for Kidney Stone Recurrence Prevention

NOSTONE
Start date: March 9, 2017
Phase: Phase 3
Study type: Interventional

The investigators plan to assess the efficacy of standard and low dose HCTZ treatment in the recurrence prevention of calcium-containing kidney stones. More specifically, the investigators aim to assess the dose-response relationship for three different dosages of HCTZ. Study intervention: HCTZ 12.5 mg, 25 mg or 50 mg once daily per os for 24 or 36 months. In addition, all patients in HCTZ treatment arms will receive state-of-the-art non-pharmacologic recommendations for stone prevention according to current guidelines. Control intervention: Placebo once daily per os for 24 to 36 months. In addition, all patients in the placebo arm will receive state-of-the-art non-pharmacologic recommendations for stone prevention according to current guidelines.

NCT ID: NCT03046888 Completed - Renal Stone Clinical Trials

ROBOTIC PYELOLITHIOTOMY VERSUS PERCUTANEOUS NEPHROLITHOTOMY (PCNL).

Start date: October 1, 2017
Phase: N/A
Study type: Interventional

Prospectively randomized study in patients with renal pelvic stones who are candidate to standard PCNL procedure. One to one, controlled clinical trial. Patients will be randomly allocated into two groups, 20 patients in each group. Group A will be scheduled to receive routine standard PCNL. Group B will be scheduled to receive Robot assisted pyelolethotomy.

NCT ID: NCT03040466 Completed - Kidney Calculi Clinical Trials

Comparing Treatment of Urolithiasis Between Disposable and Reusable Ureteroscope

Start date: August 2014
Phase: N/A
Study type: Interventional

Reusable flexible ureteroscopes are widely used to treat various upper urinary tract diseases including urinary stones. However, they require a long turnover time between procedures because of the sterilization process. Moreover, repeated use of a scope ultimately deteriorates its image quality which leads to a high maintenance cost in the long-term. A disposable digital flexible ureteroscope was released in the United States in January 2016, offering an improved image resolution, new scope performance characteristics with every case, and no need for sterilization and repair. Preliminary data from our center has demonstrated that disposable scopes shorten operative time by 25% compared to reusable fiberoptic scope and are associated with a 2/3 reduction in procedural complication rate. Therefore, treatment with disposable scopes may be more effective for patients and facilitate cost management within the hospital. Here, we propose a three-armed, prospective randomized study, comparing treatment outcomes between disposable digital, reusable fiberoptic, and reusable digital flexible ureteroscopes.

NCT ID: NCT03035812 Completed - Blood Pressure Clinical Trials

Alkalinization by Urologists & Nephrologists

AlcalUN
Start date: February 1, 2017
Phase: Phase 4
Study type: Interventional

Metabolic acidosis recovers a wide range of diseases in which an oral alkalinization could be useful. This therapeutic intervention has been said to increase extracellular volume leading to rising blood pressure. No prospective data has been published in clinical routine. Here, investigators propose to follow patients in which an oral alkalinization is indicated: blood pressure, body weight, and a clinical evaluation of the extracellular compartment will be performed at the beginning and during the follow-up of participants. The principal criterion of evaluation will be the variation in the extracellular compartment.

NCT ID: NCT03018899 Completed - Kidney Calculi Clinical Trials

Paravertebral Block Versus Epidural Anesthesia for Percutaneous Nephrolithotomy

PVB
Start date: September 2016
Phase: N/A
Study type: Interventional

This prospective, randomized study is aimed to assess the efficacy and safety of paravertebral block compared to epidural anesthesia for percutaneous nephrolithotomy. The investigators suppose that paravertebral block is not inferior in controlling the perioperative pain for percutaneous nephrolithotomy compared to epidural block.

NCT ID: NCT02938884 Completed - Nephrolithiasis Clinical Trials

Hidrate Me Smart Water Bottle Use in Patient With Nephrolithiasis

HidrateMe
Start date: December 5, 2016
Phase: N/A
Study type: Interventional

The primary objective of this study would be to determine whether utilization of this technology improves adherence to recommended increases in hydration for stone forming patients with low urine volume relative to standard techniques such as education and reading materials. We hypothesize that the addition and utilization of the smart water bottle to standard recommendations will lead to measurable increases 24 hour urine output for affected patients.

NCT ID: NCT02878148 Completed - Nephrolithiasis Clinical Trials

Conditional Imaging Prescription Strategy for Exploration of Acute Uncomplicated Renal Colic

IMAGENCO
Start date: October 17, 2016
Phase: N/A
Study type: Interventional

Prospective single centre study aiming at validating a conditional imaging strategy for diagnosis of suspected kidney stone. Consecutive Emergency department patients referred to the medical imaging department for exploration of a suspected acute uncomplicated renal colic will undergo the following interventions : systematic plain abdominal Xray, systematic ultrasonography and systematic unenhanced CT (with a reduced dose scan), in addition to clinical examination and assessment of body mass index and the Sex, Timing, Origin, Nausea, Erythrocytes (STONE) clinical prediction score for symptomatic stone. Patients will be followed up at 1 month to record the need for urologic intervention and its type. The performances of different conditional imaging strategy for the diagnosis of suspected renal colic will be assessed retrospectively. The conditional strategies tested will be based on the patient's stone score and BMI and targeted use of combined plain X-ray and ultrasonography and/or unenhanced CT. The reference diagnosis for renal colic will be made according to the finding of a ureteral stone or indirect signs of urolithiasis at unenhanced CT.