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Nephrolithiasis clinical trials

View clinical trials related to Nephrolithiasis.

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NCT ID: NCT06331546 Recruiting - Healthy Clinical Trials

Gut Oxalate Absorption in Calcium Oxalate Stone Disease

Start date: April 1, 2024
Phase: N/A
Study type: Interventional

The goal of this clinical trial study is to test if patients with idiopathic calcium oxalate kidney stones have an increased absorption of dietary oxalate, which would lead to increased urinary excretion of oxalate. The study will recruit adult patients with a history of calcium oxalate kidney stones and healthy volunteers without kidney stones. Participants will - ingest fixed diets containing low and moderately high amounts of oxalate for 5 days at a time - ingest a soluble form of oxalate and sugar preparations to test gut permeability - collect urine, blood, stool and breath sample during the fixed diets and the soluble oxalate test

NCT ID: NCT06330701 Recruiting - Kidney Calculi Clinical Trials

Stone Access and Removal (STAR) Study

STAR
Start date: January 18, 2024
Phase: N/A
Study type: Interventional

The purpose of the study is to assess procedural completion, the post-operative stone clearance and the safety profile following robotic mini-Percutaneous Nephrolithotomy (PCNL) performed with the MONARCH Platform, Urology.

NCT ID: NCT06330246 Recruiting - Urolithiasis Clinical Trials

O. Formigenes Colonization in Calcium Oxalate Kidney Stone Disease

Start date: April 1, 2024
Phase: N/A
Study type: Interventional

The goal of this trial is to test if colonization with the gut bacteria Oxalobacter formigenes leads to a reduction in urinary oxalate excretion in patients with calcium oxalate kidney stone disease. The study will recruit adult participants with a history of calcium oxalate kidney stones who are not colonized with Oxalobacter formigenes. Participants will - ingest fixed diets containing low and moderately high amounts of oxalate for 4 days at a time - collect urine, blood and stool samples during the fixed diets - ingest a preparation of live Oxalobacter formigenes to induce colonization with Oxalobacter formigenes

NCT ID: NCT06320860 Enrolling by invitation - Kidney Calculi Clinical Trials

FlexStone Enabled Kidney Stone Retrieval

Start date: March 8, 2024
Phase: N/A
Study type: Interventional

This study investigates if additional basket control in helpful during retrieval of kidney stones especially those that are difficult to reach for standard baskets.

NCT ID: NCT06288022 Not yet recruiting - Safety Issues Clinical Trials

Comparison of Total Tubeless Mini-PCNL Versus Tubeless Mini-PCNL

Start date: April 1, 2024
Phase: N/A
Study type: Interventional

Limited literature has focused on the use of totally tubeless mini-percutaneous nephrolithotomy (Mini-PCNL) for the treatment of large renal stones. This Randomized Controlled trial aims to compare complication and safety of Mini-PCNL between total tubeless and tubeless Mini-PCNL.

NCT ID: NCT06269783 Recruiting - Urolithiasis Clinical Trials

Dual-process Mechanisms of Action for sipIT Intervention Effects in Patients With Urolithiasis

Start date: January 10, 2024
Phase: N/A
Study type: Interventional

The purpose of this study is to clarify the fundamental processes underlying behavior change, maintenance, and adherence during and after a 3-month fluid intake intervention period.

NCT ID: NCT06266793 Not yet recruiting - Nephrolithiasis Clinical Trials

Comparison of Holmium Laser and Thulium Laser for Mini PCNL

HOTLaser
Start date: March 1, 2024
Phase: N/A
Study type: Interventional

This is a single institution, single surgeon, randomized controlled trial to evaluate the Boston Scientific Lumenis Pulse 120H Moses 2.0 holmium laser versus the Olympus Soltive Superpulsed thulium fiber laser (TFL) for medium-to-large stones in the mini PCNL setting.

NCT ID: NCT06249243 Not yet recruiting - Clinical trials for Urinary System Disorders in IBD Patients

Affection of Renal and Urinary System in IBD Patients

Start date: February 20, 2024
Phase:
Study type: Observational

Detection and classification of different renal and urinary affection in patients with IBD that attended to Assist University Hospitals

NCT ID: NCT06249100 Recruiting - Renal Stone Clinical Trials

Flexible Mini Percutaneous Nephrolithotomy vs Retrograde Intra-renal Surgery

Start date: January 1, 2024
Phase: Phase 2/Phase 3
Study type: Interventional

The use of flexible ureteroscopy and minimally-invasive percutaneous techniques, which utilize smaller tract sizes, has been established as a way to decrease the invasiveness of procedures and improve patient outcomes compared to conventional percutaneous nephrolithotomy (PCNL) and flexible mini-PCNL has emerged as a novel technique previously first as an auxiliary procedure and then as a standalone technique. This study aims to assess the feasibility and effectiveness of flexible nephoscopy in improving stone clearance compared to standard retrograde intrarenal surgery using a flexible ureteroscope.

NCT ID: NCT06210425 Recruiting - Sepsis Clinical Trials

Is Re-examination of Urine Culture Necessary for Patients With Preoperative Positive Results in Predicting Infectious Complications Related to Mini-Percutaneous Nephrolithotomy?

Start date: March 1, 2021
Phase:
Study type: Observational

Objective To explore the predictive value of urine culture re-examination in identifying infectious complications associated with mini-PCNL in patients with preoperative positive urine culture who were treated with sensitive antibiotics. Methods Prospective and consecutive clinical data were collected from patients whose preoperative urine culture was positive and who underwent PCNL at the Department of Urology, the First Affiliated Hospital of Guangzhou Medical University. If patients'preoperative urine cultures were positive, they would be treated with appropriate antibiotics in accordance with the culture-antibiogram test results, and urine cultures were repeated on day 3 and day 7. Patients would undergo mini-PCNL after the treatment of sensitive antibiotics for 7 days, and the correlation between the results of urine culture on day 3 and day 7 and infectious complications related to mini-PCNL after surgery was analyzed.