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Nausea clinical trials

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NCT ID: NCT00930332 Terminated - Pain Clinical Trials

Methadone Hydrochloride as First-Line Therapy in Treating Patients With Chronic Neuropathic Cancer Pain

Start date: June 17, 2010
Phase: Phase 1
Study type: Interventional

RATIONALE: Methadone hydrochloride may reduce chronic neuropathic pain in patients with cancer. PURPOSE: This phase I trial is studying the side effects and best dose of methadone hydrochloride as first-line therapy in treating patients with chronic neuropathic cancer pain.

NCT ID: NCT00903396 Terminated - Colorectal Cancer Clinical Trials

Palonosetron Hydrochloride in Preventing Nausea and Vomiting Caused by Radiation Therapy in Patients With Primary Abdominal Cancer

Start date: September 2009
Phase: Phase 2
Study type: Interventional

RATIONALE: Palonosetron hydrochloride may prevent nausea and vomiting caused by radiation therapy. It is not yet known whether palonosetron hydrochloride is more effective than a placebo in preventing nausea and vomiting. PURPOSE: This randomized phase II trial is studying the side effects of palonosetron hydrochloride and to see how well it works in preventing nausea and vomiting caused by radiation therapy in patients with primary abdominal cancer.

NCT ID: NCT00900068 Terminated - Breast Cancer Clinical Trials

Blood Samples From Patients on a Clinical Trial to CINV During HSCT

Start date: August 2008
Phase: N/A
Study type: Observational

RATIONALE: Studying samples of blood in the laboratory from patients with cancer may help doctors learn more about nausea and vomiting caused by cancer treatment. PURPOSE: This laboratory study is looking at blood samples from patients with cancer who were treated on a clinical trial to control nausea and vomiting during donor stem cell transplant.

NCT ID: NCT00895245 Terminated - Nausea and Vomiting Clinical Trials

Fosaprepitant Dimeglumine, Palonosetron Hydrochloride, and Dexamethasone in Preventing Nausea and Vomiting Caused by Cisplatin in Patients With Stage III or Stage IV Head and Neck Cancer Undergoing Chemotherapy and Radiation Therapy

Start date: February 2009
Phase: Phase 2
Study type: Interventional

RATIONALE: Fosaprepitant dimeglumine, palonosetron hydrochloride, and dexamethasone may help lessen or prevent nausea and vomiting caused by cisplatin in patients with head and neck cancer undergoing chemotherapy and radiation therapy. PURPOSE: This phase II trial is studying how well fosaprepitant dimeglumine together with palonosetron hydrochloride and dexamethasone works in preventing nausea and vomiting caused by cisplatin in patients with stage III or stage IV head and neck cancer undergoing chemotherapy and radiation therapy.

NCT ID: NCT00888329 Terminated - Clinical trials for Postoperative Nausea and Vomiting

Aprepitant for Prevention of Postoperative Nausea and Vomiting in Elective Hysterectomy

Start date: July 2007
Phase: Phase 4
Study type: Interventional

The purpose of the study is to determine whether 40 mg aprepitant administered before surgery is effective for preventing vomiting in the first 24 hours after surgery in women undergoing elective hysterectomy.

NCT ID: NCT00761254 Terminated - Nausea Clinical Trials

Domperidone for Relief of Gastrointestinal Disorders

Start date: August 2008
Phase: N/A
Study type: Interventional

The purpose of this study is to make Domperidone available to patients with gastrointestinal disorders who have failed standard therapy and who might benefit from it.

NCT ID: NCT00720330 Terminated - Pain Clinical Trials

Lidocaine and Ketamine Versus Standard Care on Acute and Chronic Pain

Start date: July 2008
Phase: N/A
Study type: Interventional

The investigators are conducting this study to find out if intravenous (injected through the vein) infusion of lidocaine and ketamine administered with general anesthesia is as effective as a paravertebral block in lessening pain after surgery and that both of these techniques are superior to general anesthesia alone in reducing pain immediately after surgery and in the long-term.

NCT ID: NCT00716560 Terminated - Metastatic Melanoma Clinical Trials

Nausea and Vomiting In Patients Receiving Consecutive Days of Cisplatin

Start date: May 2005
Phase: N/A
Study type: Observational

The purpose of this study is to observe the incidence of nausea with systemic chemotherapy that includes consecutive days (more than one day)of cisplatin medication.

NCT ID: NCT00695487 Terminated - Nausea Clinical Trials

Does Intravenous Cannabis Reduce Postoperative Nausea and Vomiting (PONV)?

THC
Start date: July 2008
Phase: N/A
Study type: Interventional

The investigators evaluate if intravenously applied THC (Cannabis) reduces postoperative Nausea and vomiting. THC will be given during anesthesia before emergence. We measure how long and how effective it reduces PONV

NCT ID: NCT00655642 Terminated - Nausea Clinical Trials

Comparison of Ondansetron, Metoclopramide and Promethazine for the Treatment of Nausea and Vomiting in the Adult ED

Start date: March 2007
Phase: N/A
Study type: Interventional

The purpose of this study is to compare the effectiveness of ondansetron, metoclopramide, and promethazine for the treatment of nausea in the adult emergency department population. We hypothesize that a single intravenous dose of ondansetron is more effective in reducing nausea than a single IV dose of metoclopramide, promethazine or normal saline placebo in undifferentiated adult emergency department patients.