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Nausea clinical trials

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NCT ID: NCT06211088 Active, not recruiting - Clinical trials for Postoperative Nausea and Vomiting

Famotidine Versus Placebo in Emergency Pediatric Surgery as a Risk to Postoperative Nausea and Vomiting

Start date: January 1, 2023
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate the difference of the gastric volume by quantitative measurements of gastric antrum preoperatively and postoperatively by using 5mg famotidine versus placebo as a risk factor of PONV.

NCT ID: NCT06045364 Active, not recruiting - Nausea and Vomiting Clinical Trials

Effect of Glycopyrrolate on Nausea and Vomiting After ERCP Operation

Start date: October 1, 2023
Phase: Phase 1/Phase 2
Study type: Interventional

This study aims to determine the role of Glycopyrrolate in preventing postoperative nausea and vomiting of ERCP.

NCT ID: NCT05873270 Active, not recruiting - Clinical trials for Postoperative Nausea and Vomiting

Randomized, Controlled, Single-blind Exploratory Study of the Efficacy and Safety of Wrist and Ankle Acupuncture Intervention on Nausea, Vomiting and Pain After Sleeve Gastric Surgery in Women

Start date: March 23, 2023
Phase:
Study type: Observational

PONV is the most common clinical presentation after surgical procedures beyond pain. A retrospective study of our center found that the postoperative incidence of LSG was 77.4%. PONV can not only cause postoperative discomfort, but also cause serious complications such as disturbance water and electrolyte balance, wound splitting, incisional hernia, and even residual gastric leakage and aspiration pneumonia, resulting in prolonged hospital stay and increased medical costs. Wrist and ankle acupuncture is a special kind of acupuncture therapy. Through subcutaneous stimulation, the electrical signal is fed back along the nerve fiber into the cerebral cortex, without dialectical treatment, and only needs the appropriate symptoms and signs of the patient. Although only in the wrist and ankle, it can solve a series of problems in the whole body, especially nausea, vomiting and pain symptoms.

NCT ID: NCT05772676 Active, not recruiting - Obesity Clinical Trials

The Effect of Aprepitant Reducing Postoperative Nausea and Vomiting

Start date: December 1, 2022
Phase: Phase 4
Study type: Interventional

The purpose of this study is to assess the efficacy of Aprepitant + standard antiemetic regimen in reducing postoperative nausea and vomiting after laparoscopic gastric sleeve versus placebo + standard antiemetic regimen

NCT ID: NCT05618236 Active, not recruiting - Clinical trials for Postoperative Delirium

Sugammadex and Neostigmine in Pediatric Patients

Start date: November 8, 2022
Phase:
Study type: Observational [Patient Registry]

In this study, it was aimed to compare the use of sugammadex instead of neostigmine + atropine in the reversal of NMB in children undergoing lower abdominal surgery or urogenital surgery, and to compare the rates of postoperative agitation, nausea and vomiting using the FLACC scale, PAED scale and ICC parameters.After the approval of the local ethics committee and written consent from the family, patients who underwent ASA 1, 5-12 years old lower abdomen surgery or urogenital surgery in Pendik Training and Research Hospital will be included in the study. The patients included in the study will be those who were maintained with routine 2-3% sevoflurane inhalation anesthetic and 0.2mcg/kg/min remifentanil intravenous anesthetic, and decurarized with 0.5-1 mg/kg rocuronium. No drugs other than those administered by the responsible Anesthesiologist during the operation will be administered. The patients included in the study will be divided into 2 groups according to the agent used in decurarization. There is no condition for the number of patients in the group to be equal. Group N; neostigmine+atropine, GROUP S; This will be the group of patients decurarized with sugammadex. 0-45 days after patients are extubated. And at the 2nd hour, FLACC Scale (Pain Diagnostic Scale), PAED (Pediatric Anesthesia Recovery Delirium) Scale assessment methods will be compared in terms of pain and agitation. Nausea and vomiting will be noted as yes/no.

NCT ID: NCT04201769 Active, not recruiting - Clinical trials for Chemotherapy-induced Nausea and Vomiting

Dexamethasone-sparing Approach Including NEPA Against Emesis Caused by Cisplatin

LUNG-NEPA
Start date: November 25, 2016
Phase: Phase 3
Study type: Interventional

This study evaluates the possibility to reduce the total dose of dexamethasone, when administered with NEPA, to prevent chemotherapy-induced nausea and vomiting (CINV) in Non-Small Cell Lung Cancer (NSCLC) patients receiving a cisplatin-based chemotherapy

NCT ID: NCT03984214 Active, not recruiting - Clinical trials for Chemotherapy-induced Nausea and Vomiting

Efficacy and Safety of Dronabinol in the Improvement of Chemotherapy-induced and Tumor-related Symptoms in Advanced Pancreatic Cancer

Start date: December 16, 2019
Phase: Phase 3
Study type: Interventional

Aim of this phase III trial is to investigate the efficacy and safety of dronabinol (orally administered tetrahydrocannabinol (THC)) as adjuvant therapy to first-line standard chemotherapy in patients with metastatic pancreatic cancer for improvement of chemotherapy- and tumor-related symptoms applicated by individual titration up to the maximum tolerated dose.

NCT ID: NCT03645239 Active, not recruiting - Pain, Postoperative Clinical Trials

Post-operative Emesis and Pain Outcomes After Cesarean Delivery

EPOC
Start date: May 24, 2018
Phase:
Study type: Observational

Approximately 20% women who undergo cesarean delivery would suffer from severe post-operative pain, which may further increase their risks from developing postpartum depression. Predictive factors such as pre-operative pain, age and anxiety could significantly contribute to post-operative nausea and vomiting (PONV) and pain in general surgery, however little information is available with regards to cesarean delivery. The investigators would investigate the risk factors of causing post-operative emesis after cesarean delivery, and to reaffirm that there is a positive correlation between pain on local anesthetic injection, presence of mechanical temporal summation (MTS) and post-Cesarean pain scores.

NCT ID: NCT03499808 Active, not recruiting - Constipation Clinical Trials

S1702 Isatuximab in Treating Patients With Relapsed or Refractory Primary Amyloidosis

Start date: June 6, 2018
Phase: Phase 2
Study type: Interventional

This phase II trial studies how well isatuximab works in treating patients with primary amyloidosis that has come back or does not respond to treatment. Monoclonal antibodies, such as isatuximab, may interfere with the ability of cancer cells to grow and spread.

NCT ID: NCT03405324 Active, not recruiting - Clinical trials for Chemotherapy-induced Nausea and Vomiting

Effect of tDCS of the Motor Cortex on Chemotherapy Induced Nausia and Vomiting

Start date: January 1, 2018
Phase: N/A
Study type: Interventional

this work is looking for the effect of tDCS of the motor cortex on the chemotherapy induced nausea and vomiting in cancer breast patients