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Nausea clinical trials

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NCT ID: NCT06356623 Not yet recruiting - Liver Cancer Clinical Trials

A Risk Prediction Model of Postoperative Nausea and Vomiting in Patients With Liver Cancer

Start date: May 5, 2024
Phase:
Study type: Observational

PONV management has been recommended as a necessary part of enhanced recovery protocols during the perioperative period, and PONV risk assessment is, therefore, a necessary first step in determining the number of medications or strategies for prophylaxis and treatment by considering the number of modifiable and non-modifiable risk factors. However, the external validity of two commonly-used PONV prediction models for patients undergoing liver surgery is unsatisfied, and need to be updated for liver cancer populations to better inform personalized perioperative care regime and individualized decision-making in clinical practice.

NCT ID: NCT06333626 Not yet recruiting - Clinical trials for Nausea and Vomiting, Aspiration, Intraoperative

Effects of an Oral Multi-vitamin Carbohydrate Beverage on Intraoperative Nausea and Vomiting

Start date: April 1, 2024
Phase: N/A
Study type: Interventional

Nausea and vomiting are common and unpleasant symptoms for pregnant women during cesarean section, which can lead to aspiration, a serious complication that can cause pneumonia. Our study aimed to evaluate the effects of oral multi-vitamin carbohydrate beverage on maternal intraoperative nausea and vomiting by gastric ultrasound.

NCT ID: NCT06331520 Not yet recruiting - Clinical trials for Chemotherapy-induced Nausea and Vomiting

NEPA Combined With Olanzapine, Dexamethasone-sparing for the Effect of CINV in Patients Receiving HEC Regimens

Start date: May 1, 2024
Phase: Phase 3
Study type: Interventional

The objective of this Prospective, randomized, non inferiority phase III trial is to confirm the efficacy and saftey of dexamethasone-sparing combined with netupitant/palonostron and olanzapine for the prevention of chemotherapy-induced nausea and vomiting in patients receiving highly emetogenic chemotherapy.

NCT ID: NCT06288542 Not yet recruiting - Clinical trials for Effect of Dextrose on Postoperative Nausea and Vomiting

Preoperative Dextrose Infusion and Postoperative Nausea and Vomiting

Start date: March 1, 2024
Phase: N/A
Study type: Interventional

This research aims to investigate the efficacy of preoperative intravenous infusion of dextrose 5% during fasting in lowering the incidence and severity of post-operative nausea and vomiting related to laparoscopic gynaecologic procedures

NCT ID: NCT06224894 Not yet recruiting - Cancer Clinical Trials

The Effect of Music Therapy on Nausea, Vomiting and Anxiety Levels in Children

Start date: February 1, 2024
Phase: N/A
Study type: Interventional

This study will be conducted with a randomized controlled study model to examine the effect of music therapy on nausea, vomiting and anxiety levels in children diagnosed with oncological cancer receiving cisplatin. The research is planned to be carried out at Dokuz Eylül University Nevvar-Salih İşgören Children's Hospital Pediatric Hematology-Oncology Clinic between December 2023 and December 2024. There is no application for music therapy in the operation of this hospital and clinic.

NCT ID: NCT06137924 Not yet recruiting - Pain, Postoperative Clinical Trials

Intraoperative Autonomic Neural Blockade

ANB
Start date: December 2, 2023
Phase: Phase 3
Study type: Interventional

The duration of the effect of autonomic neural blockade (ANB) is the most critical limitation for successful clinical application. The analgesic effect using only 0.5% bupivacaine may wear off after 12 to 18 hours. We have prolonged this effect using a combination of bupivacaine and dexamethasone. In this protocol, we aim to study three different local anesthetic combinations to prolong the effect of the ANB.

NCT ID: NCT06060418 Not yet recruiting - Clinical trials for Postoperative Nausea and Vomiting

Effect of Lavender Aromatherapy on Post-Operative Nausea and Vomiting Among Laparotomy Patients

Start date: June 2024
Phase: N/A
Study type: Interventional

Post-operative nausea and vomiting are critical problems that occur commonly after the administration of general anesthesia, which can lead to serious health complications such as hemorrhage, electrolyte imbalance and ultimate shock. To prevent these complications, antiemetic drugs are often administered, but they can cause side effects as well as increased healthcare costs. As concerns regarding the side effects of antiemetic drugs have grown, there has been an increased interest in using non-pharmacologic interventions, such as aromatherapy, as an alternative approach to preventing post-operative nausea and vomiting. It involves the therapeutic use of essential oils, and lavender essential oil, in particular, is commonly used for various digestive problems including nausea, and vomiting. Therefore, a key question for a health care professional is how to prevent post-operative nausea and vomiting in best possible manner? To address this question, a study will be conducted in District Head Quarter Sheikhupura, aiming to evaluate the effectiveness of lavender essential oil aromatherapy in reducing post-operative nausea and vomiting among patients admitted for laparotomy under general anesthesia. This study will be a Randomized control trial with the study population consisting of admitted patients after laparotomy under general anesthesia. The sample size will be 70, who will be divided into two groups, each consisting of 35 participants. A convenience sampling technique will be employed for the recruitment of participants. After that, the participants will be randomized into control and intervention groups by computer-generated table numbers in accordance with the inclusion criteria that is, 18-65 age, both genders, laparotomy under general anesthesia, clinically stable, and susceptive to post-op nausea and vomiting within 24hrs following the surgery. whereas, the patients with respiratory diseases, allergies, infections, reversal laparotomy within short duration, having any kind of addiction, those who move to the intensive care unit, those with a history of motion sickness, history of pre-op nausea and vomiting and those who start oral or NG feed before 24hrs will not be part of this study. The data will be analyzed by using Statistical Package for Social Sciences version 22.

NCT ID: NCT06055192 Not yet recruiting - Nausea Clinical Trials

Prevalence and Burden of Nausea and Vomiting in Pregnant Women in Switzerland: Survey Purity 2022

Start date: September 2023
Phase:
Study type: Observational

The latest data on the prevalence of nausea in pregnancy in Switzerland is dated 2015 but has been hypothesised that the recent introduction on the market of new drugs against this symptom could modify its epidemiology. For this reason, we have planned the present survey, calculating an adequate sample size of Swiss pregnant women (the population of interest) and, according to a cross-sectional design, planning the collection of response variables with the aim of estimating the prevalence of burden and nausea and vomiting in pregnancy

NCT ID: NCT06009211 Not yet recruiting - Nausea Clinical Trials

Impact of Aromatherapy on Nausea in Hospitalized Children Undergoing Rehabilitation

Start date: May 1, 2024
Phase:
Study type: Observational

Children, ages 8 - 17, will be enrolled in a research study about the impact of aromatherapy on nausea in the pediatric rehabilitation unit.

NCT ID: NCT05961722 Not yet recruiting - Anxiety Clinical Trials

The Effect of Choosing of Preoperative Intravenous Fluid Type on the Postoperative Nausea, Vomiting, Anxiety and Pain After Laparoscopic Cholecystectomy

Start date: August 1, 2023
Phase:
Study type: Observational

In this study, it was aimed to investigate the relationship between postoperative nausea and vomiting, anxiety levels and pain scores in the postoperative period according to dosing and choosing of intravenous fluid type that the patients received in the preoperative period.